Mar 1, 2014 02:06PM Monis wrote:
Well, I have been on Tamoxifen for about 2 1/2 months, and I definitely have noticed an increase in moodiness. Looking back at the past couple of months, I think I had particular bad spells of depression, hopelessness and crying prior to getting my period, so probably hormone related, but much worse than pre-Tamoxifen. This last month, things seem better. I have also been on Effexor 150mg for many years for anxiety and depression, so I'm sure it must be helping with SE's. I really haven't had any hot flashes, maybe just warm flushes. If you continue to suffer with moodiness/depression, ask your doctor about getting an RX for Effexor. They prescribe it to help with hot flashes, and it should help with your emotions as well.