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Topic: Pharmacy is telling me that Teva is discontinuing Tamoxifen

Forum: Hormonal Therapy - Before, During, and After —

Risks and benefits, side effects, and costs of anti-estrogen medications. Note: Please remember that there are good experiences and bad with ALL treatments and this is a safe place to share YOUR experience, not to be influenced or influence others.

Posted on: Aug 10, 2016 06:10AM

Crescent5 wrote:

Anyone else hear this? Teva brand is the only tamoxifen I can tolerate, so I'm particularly disappointed. I'm also not entirely sure this is true. I sent an email to Teva, but wondering in the meantime if anyone else has been told this.

Thank you =)

Dx: ALH, LCIS 10/10, PLCIS 11/10 ~ PBM 1/13/12 ILC 4mm & 7mm found post MX Stage 1 Grade 2 ER/PR+ HER2- 0/9 nodes Oncotype Score = 6, Tamoxifen 4/12 ~I want this sh*t to leave me alone Dx 1/13/2012, ILC, <1cm, Stage IB, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Aug 10, 2016 10:56AM jojo9999 wrote:

Crescent5 - what is the number imprinted on your teva pills (not the bottle, but the pill) ? its the number that matters. there have been a number of mergers among the generic manufacturers. is it possible the name is changing but not the actual manufacturing of the pill? I use teva and will be refilling soon and will ask.

Dx 8/2014, ILC, Right, 1cm, Stage IIA, Grade 1, 1/4 nodes, ER+/PR+, HER2- (DUAL) Surgery 9/7/2014 Mastectomy: Left, Right; Reconstruction (left); Reconstruction (right) Radiation Therapy 11/10/2014 Hormonal Therapy 12/22/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Aug 10, 2016 01:34PM kcat2013 wrote:

I recently filled my Tam. prescription and was surprised to see that it was made by Mylan not Teva. I've used Teva the whole time I've taken Tamoxifen. Nothing was said on the script except noting that the manufacturer was different than what was previously taken. I prefer the Teva pills, they are smooth and easier to swallow (I'm a pill swallowing wimp).


34 at diagnosis Dx 8/2013, IDC, <1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR-, HER2+ Surgery 9/3/2013 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 10/24/2013 AC + T (Taxol) Targeted Therapy 2/6/2014 Herceptin (trastuzumab) Surgery 6/19/2014 Reconstruction (left); Reconstruction (right)
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Aug 10, 2016 02:28PM - edited Aug 10, 2016 02:28PM by Nancy2581

well this isn't good. I also use the Teva brand . Several months ago they tried to switch me to a different manufacturer. I said no switch me back which they did. Now I'm gonna call the pharmacy and as

2.8 cm tumor with LVI Dx 6/11/2014, IDC, Right, 2cm, Stage IIB, Grade 1, 1/3 nodes, ER+/PR+, HER2- (IHC) Surgery 6/24/2014 Lumpectomy: Right; Lymph node removal: Right, Sentinel Chemotherapy 7/21/2014 AC + T (Taxol) Hormonal Therapy 1/27/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 1/28/2015 Whole-breast: Breast, Lymph nodes Hormonal Therapy 12/17/2017 Femara (letrozole)
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Aug 10, 2016 02:39PM ErenTo wrote:

I've been using Teva from beginning and when I filled my last Tam prescription around March, pharmacy told me that Teva is out of stock and it might take a while and asked me if I wanted to wait or go for another brand. Having had good experience with Teva I waited a bit and then had to order Watson, which was equally good without any issue (and the pill is smaller as a bonus!). I ended up switching to an AI but it had nothing to do with side effect.

Survived an unexplained sudden cardiac arrest b/w surgery and chemo (while attending a chemo info session at the hospital). Code blue, CPR, induced coma, ICU, ICD. Escaped alive with heart and brain unscathed! Dx 12/8/2014, IDC, Left, 2cm, Stage IIIA, Grade 3, 6/13 nodes, ER+/PR+, HER2- (FISH) Surgery 1/12/2015 Lumpectomy: Left Chemotherapy 3/20/2015 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil), Taxotere (docetaxel) Hormonal Therapy 7/24/2015 Aromasin (exemestane), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone), Zoladex (goserelin) Radiation Therapy 8/4/2015 Breast, Lymph nodes
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Aug 10, 2016 02:50PM Nancy2581 wrote:

I just called TEVA and yes they are no longer making tamoxifen. Mayne Pharmaceutical is. I called Mayne and they told me they will not be changing the formula. You can ask your Pharmacy to order from them

2.8 cm tumor with LVI Dx 6/11/2014, IDC, Right, 2cm, Stage IIB, Grade 1, 1/3 nodes, ER+/PR+, HER2- (IHC) Surgery 6/24/2014 Lumpectomy: Right; Lymph node removal: Right, Sentinel Chemotherapy 7/21/2014 AC + T (Taxol) Hormonal Therapy 1/27/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 1/28/2015 Whole-breast: Breast, Lymph nodes Hormonal Therapy 12/17/2017 Femara (letrozole)
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Aug 10, 2016 05:37PM ksusan wrote:

My last refill was Mayne. However, the code on the pill was still listed as Teva's.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Aug 10, 2016 07:02PM 70charger wrote:

Interesting. I've been on Nolvadex-D tamoxifen made by AstraZeneca . Today I got my new pills & they are Teva with a sticker that they look the different but are same as my previous pills.

Dx 7/11/2013, IDC, 2cm, Stage I, Grade 3, 0/6 nodes, ER+/PR+, HER2- Surgery 8/8/2013 Lumpectomy: Right Surgery 8/8/2013 Lymph node removal: Right, Sentinel Dx 8/21/2013, DCIS, 2cm, Grade 3 Chemotherapy 9/10/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 12/8/2013 Breast Hormonal Therapy 12/12/2013 Arimidex (anastrozole), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Arimidex (anastrozole)
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Aug 15, 2016 04:10PM 70charger wrote:

bump


Dx 7/11/2013, IDC, 2cm, Stage I, Grade 3, 0/6 nodes, ER+/PR+, HER2- Surgery 8/8/2013 Lumpectomy: Right Surgery 8/8/2013 Lymph node removal: Right, Sentinel Dx 8/21/2013, DCIS, 2cm, Grade 3 Chemotherapy 9/10/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 12/8/2013 Breast Hormonal Therapy 12/12/2013 Arimidex (anastrozole), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Arimidex (anastrozole)
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Aug 17, 2016 01:51PM TwoHobbies wrote:

Everyone, Mayne bought 42 Teva and Allergan products including tamoxifen. they are in NC and are expanding their manufacturing facility there, although i dont kniw if that mesns tamoxifen is/will be manufactured there

Round 1 -bmx, tug flap reconstruction, tamoxifen. Local Recurrence-excision, TCx4, radiation, Zoladex, Anastrazole. Dx 2/22/2011, IDC, 2cm, Stage IIA, Grade 2, 0/7 nodes, ER+/PR+, HER2- Dx 4/25/2013, <1cm, Grade 2, 0/1 nodes, ER+/PR+, HER2-
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Mar 30, 2017 11:24AM new2bc wrote:

I just found out that Tamoxifen by TEVA is discontinued. They told me they have 3 companies: Mylan, Watson, Mayne. Which one is better to get as far as fillers and side effects? I read earlier in this post that Mayne is similar to TEVA. Is it still the case? Anyone taking the pill by Mayne? Any different side effects? Thanks for your help.

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Mar 30, 2017 11:54AM ksusan wrote:

I don't think there's an answer as far as side effects--it's individual. I did better with Watson, can only get Mayne, and had a crummy time on Mylan. YMMV. For what it's worth, a friend in pharma told me that Mayne's formulation isn't expected to change.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Mar 30, 2017 12:23PM new2bc wrote:

Thanks ksusan,

Is the code on the pill from Mayne still the same as TEVA since you posted last in Aug? if not, what is the code? Thanks.

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Mar 30, 2017 04:08PM ksusan wrote:

I couldn't tell you what it used to be. Mayne is currently 93 782. The website https://www.drugs.com/imprints.php?drugname=tamoxifen says this imprint is manufactured by Teva.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Mar 30, 2017 05:03PM Nancy2581 wrote:

Yes Mayne took over from Teva. They told me they were not changing the formula so I'm sticking with them. I'm still getting TEVA though, but one time it was Mayne now TEVA again - weird



2.8 cm tumor with LVI Dx 6/11/2014, IDC, Right, 2cm, Stage IIB, Grade 1, 1/3 nodes, ER+/PR+, HER2- (IHC) Surgery 6/24/2014 Lumpectomy: Right; Lymph node removal: Right, Sentinel Chemotherapy 7/21/2014 AC + T (Taxol) Hormonal Therapy 1/27/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 1/28/2015 Whole-breast: Breast, Lymph nodes Hormonal Therapy 12/17/2017 Femara (letrozole)
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Mar 30, 2017 05:04PM Lisey wrote:

I use Mayne with no issues at all. I get 90 pills for $20.

Oncotype =20, ER 95%, PR 5%, ki67= 30%, Mammoprint = Low, Blueprint = Luminal A!!!! TEs= Iron Bra of Death - not worth all the complications for foobs that I'll never feel. Flat and fealess now. Dx 5/11/2016, IDC, Right, 1cm, Stage IA, Grade 2, 0/6 nodes, ER+/PR+, HER2- Surgery 6/1/2016 Lymph node removal: Sentinel Surgery 6/14/2016 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery 7/7/2016 Mastectomy: Left, Right Hormonal Therapy 7/14/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Mar 31, 2017 09:32AM new2bc wrote:

Thank you everyone,

I have a few TEVA pills left. The code is 93 782. Have a great weekend!

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Mar 31, 2017 12:05PM ksusan wrote:

Sounds like Mayne and Teva have the same number--hoping this means an identical formulation.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Apr 3, 2017 05:57PM Zoritsa wrote:

Thanks for the post! I'm getting ready to refill my script, and was going to take it in when I did. I was switched from Teva to Mylan and have more side effects now then I did with Teva. I will ask the pharmacist if they can change it to Mayne, since it's essentially Teva and I did well on that one.

Dx 6/23/2015, IDC, Left, 1cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 7/10/2015 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 8/11/2015 Whole-breast: Breast, Lymph nodes Hormonal Therapy 10/5/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Apr 3, 2017 06:05PM ChiSandy wrote:

My pharmacist checked with his distributor, and it appears that due to mergers, spinoffs and consolidations, Roxane and even Teva may have stopped making letrozole too.

Diagnosed at 64 on routine annual mammo, no lump. OncotypeDX 16. I cried because I had no shoes...but then again, I won’t get blisters.... Dx 9/9/2015, IDC, Right, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- (IHC) Surgery 9/23/2015 Lumpectomy: Right Radiation Therapy 11/2/2015 3DCRT: Breast Hormonal Therapy 12/31/2015 Femara (letrozole)
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Apr 6, 2017 09:08AM - edited Apr 6, 2017 09:09AM by new2bc

I received my mail order prescription for Tamoxifen from Mayne company and now the numbers are different from TEVA. May be in the beginning, they still had some TEVA pills left over and now they have to make their own. The numbers from Mayne show:

WPI 2233

I will update this forum if I have any side effects after taking the ones from Mayne. If anyone is taking the pills with the same numbers, let us know if there are any new side effects.


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Apr 6, 2017 10:01AM ksusan wrote:

I just filled with Mayne and got 33 782. WPI is Watson (also no longer made, as I understand it).

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Apr 9, 2017 02:15AM new2bc wrote:

Thanks ksusan,

you are right. I asked for Mayne and they sent me pills from Watson. Did they buy Watson? I will call them on Monday. They do anything to save a buck.

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Apr 9, 2017 12:16PM ksusan wrote:

FWIW, I tolerated Watson well.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Apr 9, 2017 05:16PM jojo9999 wrote:

me too - I actually had slightly more SE with the TEVA/mayne than with Watson.

Dx 8/2014, ILC, Right, 1cm, Stage IIA, Grade 1, 1/4 nodes, ER+/PR+, HER2- (DUAL) Surgery 9/7/2014 Mastectomy: Left, Right; Reconstruction (left); Reconstruction (right) Radiation Therapy 11/10/2014 Hormonal Therapy 12/22/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Apr 14, 2017 07:48AM - edited Apr 14, 2017 07:50AM by Artista928

So should Mayne change the Teva formula, would the # change?

Dx'd at 50. Doing it all, all by myself. Stopped Letrozole after 5 weeks. Debilitating se's. Back on Tamox now. Dx 6/2/2015, IDC, Left, 6cm+, Stage IIIA, Grade 3, 1/4 nodes, ER+/PR+, HER2- (DUAL) Surgery 8/6/2015 Lymph node removal: Left, Sentinel; Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 11/3/2015 AC + T (Taxotere) Radiation Therapy 5/2/2016 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 6/28/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 12/9/2016 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Hormonal Therapy 2/14/2017 Femara (letrozole) Hormonal Therapy 3/26/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/1/2017 Reconstruction (right): Fat grafting, Silicone implant
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Apr 22, 2017 02:02AM new2bc wrote:

I called the pharmacy and requested only Mayne brand for Tamoxifen. The number on the pill is 93 78, the same as Teva.

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Jan 28, 2018 07:59PM B123 wrote:

I have tried tamoxifen nolvadex brand? On the pill it has written WPI 2233. It made me horribly sick, heaviness in low abdominal and pressure. Has anyone tried that?

Dx 8/6/2011, 2cm, Stage IB, Grade 2, 2/17 nodes, ER+/PR+, HER2-
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Jan 28, 2018 08:24PM Michelle_in_cornland wrote:

The pill distributed by Mayne, is manufactured by Teva. As long as the numerical markings are the same, it is the exact same. Otherwise, there would be new coding on the tablet.

Live free - Oncotype 14, Take things as they come and you can do it!!! Dx 8/8/2016, IDC, Right, 2cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- Surgery 8/29/2016 Radiation Therapy 10/6/2016 Whole-breast: Breast Hormonal Therapy 2/15/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Prophylactic ovary removal
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Feb 20, 2018 09:13AM shebg16 wrote:

Hi everyone! This is my first post! I'm a breast cancer survivor, it has been 3 years since my diagnosis and 2.5 years since I began my Tamoxifen treatment. I have been taking Teva's brand since I began my treatment, but a few months back my pharmacy gave me a refill by Mayne Pharma instead of Teva. I experienced horrible side effects (intense hot flashes, night sweats, depressed/weepy, lethargic, etc.). Anyway, I was able to get a switch back to Teva for the past few months and everything has been normal, status quo.
This most recent refill I received Mayne again. I actually didn't even realize the switch until I'd taken the medicine for 5-6 days and all the sudden I was experiencing all the same intense side effects again. I checked the bottle, and sure enough, I'd once again been given Mayne instead of Teva. I called my pharmacy to speak with the pharmacist. She told me that Mayne acquired Teva, and so it's possible they're only distributing their generic because she said she can see that Teva is no longer available to order. She told me she thought the formula was identical, but I'm telling you, I know my body and this is not the same. I think I have a few Teva pills left so when I get home I will check the numbers on the pills and compare, but either way it sounds like Teva will be gone moving forward.

Needless to say, I am feeling a bit panicked because the side effects from Mayne have been dreadful and I can't imagine continuing to take this brand. I guess I have a few questions: 1) is Teva definitely no longer available? 2) if I were to stick things out with Mayne, will these side effects subside? 3) do I have any other options?
While unpleasant I can deal with hot flashes and physical discomfort, but I absolutely cannot function with the depressed, sad, weepy emotional side effects.

Any help or suggestions are welcome!

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Apr 1, 2018 09:50AM jojobob wrote:

I have been on tamoxifen for 4 1/2 years. I can't wait till I'm done. I want to know what my body will do without it. Just got my first bottle of mayne. Didn't even notice until the side effects started. I know I like teva best (less intense hot flashes). This past month I'm sleeping terribly, 5-6 hot flashes a night. I really would like information from a chemist about the formulas. I've tried teva, watson, mayne and mylan.

Dx 8/8/2012, IDC, 1cm, Stage IIIA, Grade 2, 4/5 nodes, ER+/PR+, HER2+

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