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Topic: Tamoxifen and esophageal spasm?

Forum: Hormonal Therapy - Before, During, and After —

This is a safe place to share your experiences of others considering or on hormonal treatment.

Posted on: Jan 11, 2018 11:38AM - edited Jan 11, 2018 11:38AM by Herculesmulligan

Herculesmulligan wrote:

Something weird happened today. I was eating my breakfast as usual when I got an intense epigastric pain that built over 10 minutes or so. It felt like an intense pressure in my lower esophagus or upper stomach. Then I vomited part of my breakfast and felt fine. I thought I had caught a stomach virus so I called in to work but I've been absolutely fine. So my question is.... I have horrendous muscle spasms from tamoxifen but usually in my feet legs and occasionally shoulder/neck. Could this spasm be a side effect of tamoxifen too?

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Jan 11, 2018 11:45AM pupmom wrote:

Wow, does everything have to do with Tamoxifen???

Life is what happens while we're making other plans. Dx 10/18/2011, IDC, Right, 1cm, Stage IIA, Grade 1, 2/21 nodes, ER+/PR+, HER2-
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Jan 11, 2018 11:47AM Herculesmulligan wrote:

Well I don't know if this is a side effect or something entirely different. That's why I'm wondering if anyone else had experienced it.

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Jan 11, 2018 11:54AM pupmom wrote:

I've never heard anything about esophageal spasm being associated with Tamoxifen. I'll leave it at that.

Life is what happens while we're making other plans. Dx 10/18/2011, IDC, Right, 1cm, Stage IIA, Grade 1, 2/21 nodes, ER+/PR+, HER2-
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Jan 12, 2018 01:16AM Peregrinelady wrote:

It sounds like acid reflux to me. What were you eating? Have you experienced this before?
Dx 4/24/2015, IDC, Left, 2cm, Stage IIB, Grade 2, 1/2 nodes, ER+/PR+, HER2- Surgery 5/17/2015 Mastectomy: Left Hormonal Therapy 6/1/2015 Liquid tamoxifen (Soltamox) Surgery 4/18/2016 Mastectomy: Right; Prophylactic ovary removal; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Hormonal Therapy 7/31/2016 Arimidex (anastrozole) Hormonal Therapy 7/19/2020 Femara (letrozole) Hormonal Therapy 3/3/2021 Arimidex (anastrozole)
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Jan 12, 2018 02:36AM Chiarara wrote:

Sounds like gastritis, or something of that type. Yes, vomiting is listed as a less common SE. But there are many other things that can cause vomiting. Hopefully, it is a one-off occurrence

Dx 10/5/2017, LCIS/DCIS/ILC/IDC, Right, 1cm, Grade 2, 0/3 nodes, ER+/PR+, HER2- (IHC) Surgery 11/4/2017 Lumpectomy: Right; Lymph node removal: Sentinel Surgery 12/6/2017 Mastectomy: Right Hormonal Therapy 1/4/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 12, 2018 05:21AM NotVeryBrave wrote:

While I don't think it was Tamoxifen, anything is possible. I understand you wondering about that. I also had absolutely ridiculous muscle spasms while on Tamoxifen - leg and feet cramps every night repeatedly but also occasionally in my abdomen or neck. Those were especially disconcerting.


TCHP x 6 with pCR. One year of Herceptin. DTI pre-pec surgery. Quit Tamoxifen after 3 months. Dx 11/21/2016, DCIS/IDC, Left, 2cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2+ (IHC) Targeted Therapy 12/18/2016 Perjeta (pertuzumab) Targeted Therapy 12/19/2016 Herceptin (trastuzumab) Chemotherapy 12/19/2016 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 5/8/2017 Lymph node removal: Sentinel; Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Hormonal Therapy 9/8/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 6/25/2020 Evista (raloxifene)
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Jan 12, 2018 05:30AM marijen wrote:

Esophageal spasms is a real condition usuall found in women between 60 and 80.


https://www.mayoclinic.org/diseases-conditions/eso...


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Jan 12, 2018 05:53AM Herculesmulligan wrote:

Thanks fir your input guys. Marijen I read that article and I'm pretty sure that's what I had. But I just finished eating the exact same breakfast (Greek yogurt with honey, bagel thin with peanut butter, banana, tea, ice water, and a big handful of supplements and my tamoxifen) and it all went down fine. Very weird.

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Jan 13, 2018 08:07PM Artista964 wrote:

i think because we are scared into side effects, and on this board, many more people posting problems than doing fine, that that the hormonal med is the first thing to think of over other possibilities.

Dxd at 50. Went thru it all on my own by choice. Dx 6/2/2015, IDC, Left, 6cm+, Stage IIIA, Grade 3, 1/4 nodes, PR+, HER2- Surgery 8/5/2015 Lymph node removal: Left, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Chemotherapy 11/2/2015 AC + T (Taxotere) Radiation Therapy 5/3/2016 Whole-breast: Breast, Lymph nodes Hormonal Therapy 6/28/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 13, 2018 08:26PM marijen wrote:

I knew about the spasms because a relative gets them. Not all the time, once in a while and no she doesn’t have bc.


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Feb 6, 2018 04:58PM 1116lucky wrote:

I have experienced the same thing in the last month or so. Been on tamoxifen for 10 months.

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Feb 6, 2018 06:44PM gb2115 wrote:

YES!!!!

I have experienced this too, twice in the past month. Well, I think that's what happened. Sudden building back pain that started after swallowing food that was either quite dry or really cold. Chugging ice water makes it start feeling like that. It's hard to explain. Weird feeling. No vomiting though. I haven't been to the doctor about it because it went away both times (once after a couple hours) and the second time it took a day and a half---it was over the weekend and not an ER level issue especially during flu season--so I waited it out. By Monday it was gone. Reflux meds did nothing for it, and clearly I wasn't having a heart attack. Sure matches esophageal spasm symptoms though, except for I am only 39 and it's usually later in life... I have been on tamoxifen for 11 months or so. I have no clue if it's connected or if my (39 year old??!!) Esophagus is getting tired or something...

In any event, awful feeling. Interesting to hear others are getting it too.

Dx IDC in Oct 2016, stage 2A, 1.2 cm ER/PR+ Her2-, Grade 2, 1/3 nodes, Lumpectomy + rads + tam. Age 38. 5/21 Dx IDC. 1.6 cm ER/PR+, Her2 -. Gr 2. 2/2 nodes positive. AC/T. Age 42
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Feb 7, 2018 11:24AM Herculesmulligan wrote:

maybe the tamoxifen relaxes that sphincter through loss of estrogen.

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