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Jan 20, 2020 03:48PM
32B - My first MO wouldn't prescribe less than 20 mg, but that didn't make me TAKE 20 mg / day. I am only taking 10 mg / day. My current MO doesn't like it, but says some is better than none.
Based on what I cut & pasted below, my concerns were:
1) thickening of the uterine lining (including benign growths and uterine cancer) - I have seeing a gynecologist every year now and had the lining thickness measured at the first one (in December)
2) liver - the Kelsey MO would do blood tests every 3 months, but I've opted to go with the MD Anderson MO who doesn't test for liver issues. I plan to ask my PCP to include the liver blood counts in my bloodwork each year
3) changes in vision / retina - I had eye exam in Nov or Dec and will have it each year. I include the option where they take a picture instead of dilating the eyes
As far as things to watch for, the Tamoxifen support group has a file that is the "tamoxifen package leaflet" from the UK that lists the following side effects:
Very Common (may affect more than 1 in 10 people)
• Fluid retention
• Hot flushes
Common (may affect up to 1 in 10 people)
• Anaemia (a blood problem which means you have too few red blood cells)
• Increased amounts of fats in your blood (shown by blood tests)
• Allergic reactions.
• Changes in the womb (including changes to its lining and benign growths)
• Feeling light-headed
• Itching of genitals
• Thinning of your hair
• Changes in blood test of liver function
• Formation of fatty liver cells
• Leg cramps
• Muscle pain
• Increased risk of blood clots (including clot in small vessels)
• Changes in vision due to cataracts or changes to retina of your eye.
• Sensory changes (including taste disorder and numbness or tingling in the skin)
Uncommon (may affect up to 1 in 100 people)
• Blood problems. This can make you bruise more easily, get serious infections, or feel
very tired or breathless
• Changes in the amount of calcium in your blood. The signs may include feeling very
sick, being sick a lot or being thirsty. Tell your doctor if this happens because he or
she may want you to have blood tests.
• Changes to your vision and difficulty seeing.
• Swelling of the pancreas. This may cause moderate to severe pain in the stomach
• Inflammation of the lungs. The symptoms may be like pneumonia (such as feeling
short of breath and coughing).
• Liver cirrhosis (problems with your liver).
Rare (may affect up to 1 in 1,000 people)
• Severe blood problems. This can make you bruise more easily, get serious
infections, or feel very tired or breathless.
• Changes to the cornea of your eye
• Problems with the nerve that connects your retina to your brain
• Swelling of the optic nerve.
• On occasions more severe liver diseases have occurred from which some patients
have died. These liver diseases include inflammation of the liver, liver cirrhosis, liver
cell damage, reduced bile formation, and failure of the liver. Symptoms may include a
general feeling of being unwell, with or without jaundice (yellowing of the skin and
• Cells normally only found in the lining of the womb found elsewhere in your body,
cysts on the ovaries, and cancer (the signs of this are given above).
• Non-cancerous mass in the inner lining of the vagina (called vaginal polyp).
Very Rare (may affect up to 1 in 10,000 people)
• Inflammation of the skin characterized by rash or erythema, very often on areas
exposed to light (a condition called cutaneous lupus erythematosus).
• A skin condition characterised by skin blisters in areas exposed to the light, this is
due to the increased liver production of a special group of cell pigments
• Radiation recall - skin rash involving redness, swelling, and/or blistering (like severe
sunburn) of the skin after receiving radiation therapy
Diag. 4/19/2019 ER+ PR+ HER2 neg Lumpectomy 5/29/2019 IDC w/ DICS 2.0 cm Grade 3