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Jan 11, 2008 10:44AM
, edited Nov 9, 2013 12:17PM
Maybe this will help with your decision.
Who should not use natural progesterone cream?
Women with breast cancer or a past history of breast cancer:
This is the only group of women at any age that I advise to avoid using even low doses of transdermal progesterone or Prometrium capsules without consulting with their oncologist beforehand. We simply don't know enough about the outcome either way. It's quite possible that certain tumors may not be affected, but until we know more, I think it is clear that the possible risks could outweigh the benefits here.
Women who note adverse effects with use of natural progesterone:
Some women will metabolize extra progesterone into estrogen - we call these women "highly estrogenic." They tend to respond quickly to supplemental progesterone with increased breast tenderness (particularly during ovulation) and irregular spotting or bleeding. The closer this kind of woman is to menopause, the more cautious she should be with any form of progesterone. With the right medical practitioner and a deep understanding of her whole health picture, it can be possible for such a woman to actually change the way she metabolizes progesterone to make it safe to supplement with bioidentical forms.
Post menopausal women:
Out of an abundance of caution, it is best not to use any form of progestogen, including progesterone, if a woman is more than two years beyond her last period, unless she is on estrogen.
It would also seem most prudent (at this stage of scientific knowledge) for a woman to not take additional hormones, including progesterone, for more than a total of five years. In this case, the reason for avoiding progesterone has more to do with the natural evolution of hormones in the body than with any identifiably increased risk. After menopause, it is natural for your body's estrogen levels to taper off - so, fittingly, should your progesterone levels.
If, however, you are using estrogen and have a uterus, you must also use some form of progestogen to counter the effects of the estrogen on the uterine cells. The use of (bioidentical) Prometrium is recommended for this circumstance, as studies using progesterone cream are conflicting and very few. As with estrogen supplementation, our recommendation is that it be used for a short period and no longer than five years, at least until more information is available.
Edited by Mods to update link