Feb 2, 2011 04:24PM SJW1 wrote:
I was diagnosed with DCIS in 2007. I started using bio-identical progesterone cream shortly after that. This is not the same stuff as the synthetic progesterone tested in the Women's Health Initiative Study. That study showed that synthetic estrogen when given with synthetic progesterone increased your risk of BC.
While synthetic progesterone and estrogen do not have the same chemical composition as the progesterone and estrogen your body makes, bio-identicals are identical to what your body makes.
When I asked my surgeon about this, she said I should not use or take any other type of bio-identical or synthetic HRT, other than bio-identical progesterone. This is because, if you are ER+, any type of estrogen can possibly encourage cancer growth when it binds with estrogen receptors.
If you are PR+, when the bio-identical progesterone binds with the progesterone receptor it has a very different effect and actually encourages cancer cell death. There are many studies showing the preventative effect of bio-identical progesterone.
I hope my explanation makes sense. Please feel free to send me a PM if you have questions or want to discuss this at all.