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Topic: Magnesium

Forum: Complementary and Holistic Medicine and Treatment — Complementary medicine refers to treatments that are used WITH standard treatment. Holistic medicine is a term used to describe therapies that attempt to treat the patient as a whole person.

Posted on: Aug 18, 2021 02:41PM

Waves2Stars wrote:

I’ve been taking mag for years for SVT and sleep. I was planning to continue when I start tam. But I’ve read on pubmed that there’s a mechanism in which it feeds BC tumor growth. Obviously, once the tumor is removed, I guess it won’t be growing, but I don’t understand if it actually promotes BC cell initiation or just promotes growth once it goes from cell to tumor.

I’m sorry if I sound so ignorant about this. I understand different sorts of cardiac issues and Parkinson’s, but this cancer thing is so complex! It’s a whole other universe to me.

DX @ 47. IDC 2 cm, Luminal B Dx 7/19/2021, IDC, Left, 2cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Surgery 9/1/2021 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Stacked DIEP flap Hormonal Therapy 9/20/2021 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Aug 18, 2021 08:07PM Monarchandthemilkweed wrote:

I’m interested in the answer too. I always have tsken magnesium for sleep as well. I stopped at diagnosis and haven’t resumed but was planning to after chemo.

Sarah, Chek2 positive Dx 3/11/2021, IDC, Left, <1cm, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 5/9/2021 Lymph node removal: Sentinel; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 6/27/2021 Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Aug 22, 2021 07:24PM Bayla wrote:

Following. I take magnesium citrate for multiple reasons including nerve and muscle health for my back pain, migraine prevention, and normal bowel. When I asked my MO about my supplements, he would not engage in a conversation and said to take what I want after standard treatment. I never thought about stopping magnesium, but now I will question it. Thanks.

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Aug 22, 2021 07:41PM ShetlandPony wrote:

Waves, could you give us the citation so we can read the article that concerns you? I looked up magnesium on the Memorial Sloan Kettering Cancer Center integrative medicine site, where they provide information about herbs, botanicals, and supplements. For magnesium they describe many benefits, and what drugs and health conditions it may interact with, but it does not describe any concerns with breast cancer or with cancer therapy, except to say that monoclonal antibody treatments may cause low magnesium. I take it for bone health, with my onc's ok.

https://www.mskcc.org/cancer-care/integrative-medicine/herbs/magnesium



2011 Stage I ITCs sn, premenopausal, Oncotype 16. 2014 Stage IV mets breast,liver. TaxolNEAD. Ibrance+letrozole 2yrs. Fas+afinitor nope. XelodaNEAD 2yrs. Eribulin,Doxil nope. SUMMIT FaslodexHerceptinNeratinib for Her2mut NEAD Dx 2011, ILC, 1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Dx 2014, ILC, 2cm, Stage IV, metastasized to liver/other, Grade 2, ER+/PR+, HER2- Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole-breast: Breast Surgery Lumpectomy
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Aug 22, 2021 09:03PM - edited Aug 22, 2021 09:04PM by Esther01

My IMD has had me on 200-400 mg magnesium daily since diagnosis (Optimag Neuro by Xymogen). My SpectraCell soon after diagnosis showed that I was deficient.

I looked magnesium up in the book that I have been reading by Dr. Mark Stengler and Dr. Paul Anderson (2018: Outside the Box Cancer Therapies, Hay House Inc.). Here's what they say on pg 54 about magnesium supplementation during chemo:

"Alkylating agents that are platinum-based... are given to approximately half of all patients undergoing chemotherapy... These anticancer agents have shown in multiple studies to cause magnesium deficiency." It says that cisplatin, carboplatin, oxaliplatin, pyriplatin and phenenthriplatin are platinum-based. It then goes on to describe the symptoms of magnesium deficiency (muscle cramps, fatigue, insomnia, etc).

It further reads, "Research has shown that between 41 percent and 100 percent of patients receiving low dose cisplatin became deficient in magnesium. Research has also shown that magnesium supplementation during platinum-based chemotherapy signfiicantly reduces the degree of low magnesium levels. It is recommended that everyone on this type of chemotherapy take supplemental magnesium either orally (400 mg daily) or intravenously. Speak with your oncologist and integrative doctor about magnesium supplementation as part of your treatment."

I really like this book because they include over 300 footnoted studies in each chapter, and I had never seen the majority of the studies they highlight. Here are the studies to which they were referring here:

TC Johnstone et al, "Understanding and improving platinum anticancer drugs- phenanthriplatin" in Anticancer Research, 2014, 34(1): 471-476.

JE Buckley et al., "Hypomagnesemia after cisplatin combination chemotherapy," Archives of Internal Medicine, 1984 (sounds like an old study), found at https://doi.org/10.1001/archinte.1984.003502200630...

E. Hodgkinson et al., "Magnesium depletion in patients receiving cisplatin-based chemotherapy," Clinical Oncology (Royal College of Radiologists (Great Britain), 2006 Nov, 18(9):710-8.

Blessings,

Esther


Grateful to Jesus, that His love finally broke through to me. "With one touch, You just rolled away the stone that held my heart," - Lyrics by Keith Green, " 7 weeks of Radiation including supraclavicular nodes. Dx 12/2020, IDC, Stage IIB, 5/11 nodes, ER+/PR+, HER2- Hormonal Therapy 12/19/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 6/8/2021 Lumpectomy; Lymph node removal: Sentinel; Reconstruction (left) Radiation Therapy 8/3/2021 Whole-breast: Breast, Lymph nodes
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Aug 22, 2021 09:10PM Esther01 wrote:

Oops, I meant to include the front cover.

Grateful to Jesus, that His love finally broke through to me. "With one touch, You just rolled away the stone that held my heart," - Lyrics by Keith Green, " 7 weeks of Radiation including supraclavicular nodes. Dx 12/2020, IDC, Stage IIB, 5/11 nodes, ER+/PR+, HER2- Hormonal Therapy 12/19/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 6/8/2021 Lumpectomy; Lymph node removal: Sentinel; Reconstruction (left) Radiation Therapy 8/3/2021 Whole-breast: Breast, Lymph nodes
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Aug 22, 2021 10:20PM Waves2Stars wrote:

The studies I’ve seen talk about it promoting tumor growth.

https://link.springer.com/article/10.1007/s12011-017-1207-8

https://pubmed.ncbi.nlm.nih.gov/32761610/

Since I don’t have access, I can’t find out how much an association there is or if it’s specific to BC subtypes. I’m really curious

DX @ 47. IDC 2 cm, Luminal B Dx 7/19/2021, IDC, Left, 2cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Surgery 9/1/2021 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Stacked DIEP flap Hormonal Therapy 9/20/2021 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Sep 17, 2021 04:38PM purple32 wrote:

I take MG with my CA or they say CA doesn't work. UGH I have osteoporosis


BILAT LE! from 5.12.12.LX DX 3/2012 IDC <1 cm stage 1 GR 1 ( 0/2 nodes) ER PR pos HER2- RECURRENCE same breast Jan 2020 LX FEB 2020 . NO rads or hormones. Dx 3/2012, IDC, Left, <1cm, Grade 1, 0/2 nodes, ER+/PR+, HER2+ Surgery 5/1/2012 Lumpectomy: Left
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Sep 23, 2021 06:03PM - edited Sep 24, 2021 05:26PM by moth

I have a copy of one of those articles wavestostars if you want it - the first one. It's more about the cell biology & how during early oncogenesis the cell take up a lot of Mg. lmk if you want it.

They also linked to this article which is open access; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC47594...

"The inverse association of higher total magnesium intake with all-cause mortality was primarily presented among postmenopausal women and was stronger among women who had a high Ca:Mg intake ratio (>2.59). There were no clear associations for prognosis with intake of calcium. We found that magnesium intake alone may improve overall survival following breast cancer, and the association may be stronger among those with high Ca:Mg intake ratio."

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/13/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/18/2020 Tecentriq (atezolizumab) Chemotherapy 11/25/2020 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 12/8/2020 External Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, ER+/PR-, HER2- (IHC) Hormonal Therapy 12/15/2020 Femara (letrozole) Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/2/2021 External: Bone
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Sep 24, 2021 04:05PM Waves2Stars wrote:

Thank you, Moth! There is probably a difference in cellular uptake of Mg vs a causal connection. Also, thanks for the link to the second article!

DX @ 47. IDC 2 cm, Luminal B Dx 7/19/2021, IDC, Left, 2cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Surgery 9/1/2021 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Stacked DIEP flap Hormonal Therapy 9/20/2021 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Sep 24, 2021 09:53PM BlueGirlRedState wrote:

I did find increasing Mg helped with muscle cramps (calf) while taking Tamoxifen 2009-2014. At the tie I was taking Ca/Mg that had reocmmended 100% Ca and 50% Mg. I was not worried about Mg since it seemed abundant in many foods I ate. When I switched to 100% Mg and 50% Ca, the cramps almost disappeared. Also I was a little worried about how much Ca since too much ( how much is too much??) seems to be linked to heart issues for women. I eat quite a bit of yogurt, cheese, milk. NIH fact sheet on Mg. I guess I'll use more pumpkin seeds on the salads. I wonder if kobocha or some of the other sweet squashes I planted have it. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/

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Sep 25, 2021 04:47PM Carlsoda wrote:

I’ve been taking 400mg of magnesium glycinate for years and years and my oncologist never said anything about it. She did take me off tumeric and my very high Vit c during chemo. I know magnesium really helps with my foot craps and over all joint soreness.

Age: 51 @ diagnosis. Oncotype Result: 16 Dx 4/26/2016, IDC, Left, 1cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 5/4/2016 Lumpectomy: Left; Lymph node removal: Left, Underarm/Axillary Radiation Therapy 6/20/2016 Whole-breast: Breast Hormonal Therapy 8/10/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 3/31/2021, IDC, Left, 1cm, Stage IA, Grade 3, ER+/PR+, HER2- (FISH) Surgery 5/4/2021 Lymph node removal: Underarm/Axillary; Mastectomy: Left Chemotherapy 6/2/2021 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 9/5/2021 Femara (letrozole) Hormonal Therapy 10/2/2021 Zoladex (goserelin)

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