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Topic: mets to lung

Forum: Stage IV/Metastatic Breast Cancer ONLY —

Please respect that this forum is for members with stage IV/metastatic breast cancer only. There is a separate forum for caregivers and friends: Caring for Someone with Stage 4 or Mets.

Posted on: Jan 6, 2012 08:53AM - edited Oct 12, 2013 07:32AM by bhd1

bhd1 wrote:

hello. i got scan rusults yesterday. looks like abraxane is not working, since cancer is spreading. i am going on navelbine now. any words of encouragement? thanks. i am new to the boards, happy to find you all

barb

barb Dx 9/22/2011, IDC, 3cm, Stage IV, Grade 3, ER-/PR-, HER2+
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Jun 6, 2021 07:31AM rachel5738 wrote:

Hi all - sadly the doc attempt at needle biopsy of right lung did not work. Lung collapse, chest tube were the results. Now we try again but this time in larger surgery which I was hoping to avoid. Anyone had the open biopsy and know about healing process

April 2021; Stage 4, lung Mets; August 2020;Breast Cancer Stage II, Grade 1: Treatment Plan: FEC-T X6/Rads 25+5/Tamoxifen 5 years; Cervical Cancer Stage 1B, Treatment plan: Rad Hyst Dx 7/5/2010, IDC, 1cm, Stage II, Grade 1, 1/7 nodes, ER+/PR+, HER2- Dx 4/28/2021, Right, Stage IV, metastasized to lungs
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Jun 6, 2021 11:05AM Sadiesservant wrote:

Hi Rachel, I’m sorry to hear about the ordeal you are going through. I can’t really help as I had pleural mets so a biopsy would have been difficult. Generally my MO is not keen on biopsies as he worries about the risks which you have experienced. I hope the surgery goes well.

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Jun 9, 2021 08:50PM rachel5738 wrote:

Thanks Dee. The bone scan did show some sort of abnormality in left pelvis. I had MRI today of pelvis to take another look. Lung wedge biopsy surgery next Tuesday. I’ll be spending a couple of days in hospital after but my hope is that we finally get all the detail on the nodules so I know what’s next. Waiting is the worst.

April 2021; Stage 4, lung Mets; August 2020;Breast Cancer Stage II, Grade 1: Treatment Plan: FEC-T X6/Rads 25+5/Tamoxifen 5 years; Cervical Cancer Stage 1B, Treatment plan: Rad Hyst Dx 7/5/2010, IDC, 1cm, Stage II, Grade 1, 1/7 nodes, ER+/PR+, HER2- Dx 4/28/2021, Right, Stage IV, metastasized to lungs
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Jul 2, 2021 09:10PM rachel5738 wrote:

Hi Dee. Well I am recovering from wedge resection surgery that was performed on my right lung two weeks ago I have had awful time getting back up and going. This surgery took the wind out of my sails for the last couple of weeks. I have meeting with oncologist and surgeon this morning to kearn more about the tumor and next steps. The good news is that after a separate MRI - the docs determined that they do not believe the spot on my pelvis to be anything cancerous so that was good news. Therefore, I’m dealing with the Mets to lung which they cut out in wedge resection. I’m not sure what treatment would be next as there is nothing else but I assume they will want to be sure it’s all gone in lungs? Any ideas?

April 2021; Stage 4, lung Mets; August 2020;Breast Cancer Stage II, Grade 1: Treatment Plan: FEC-T X6/Rads 25+5/Tamoxifen 5 years; Cervical Cancer Stage 1B, Treatment plan: Rad Hyst Dx 7/5/2010, IDC, 1cm, Stage II, Grade 1, 1/7 nodes, ER+/PR+, HER2- Dx 4/28/2021, Right, Stage IV, metastasized to lungs
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Aug 11, 2021 02:46PM Karenfizedbo15 wrote:

Hi All, just found this thread but recognise several names.

Not great news for me. 2nd Scan shows fluid on lung again though small - and nodes in pleura slightly larger. Plan short term is to increase Xeloda dosage by extending from 10 to 14 days to see if the dose was maybe just too small to be effective. Bearingin mind the SEs were awful initially and are now fine. My MO was clearly surprised as my first scan was so good. We'll try this for 2 cycles and rescan. She said this is not normal practice, but neither was my severe initial reaction expected. Cross posting to xeloda / lung mets threads for any advice.

Feeling the heavy loss of so many of us recently and I might be wise to take a break from BCO for a while just to keep my head straight.

Surgery 9/6/2007 Lymph node removal: Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2- Dx 2021, Stage IV, metastasized to bone Chemotherapy 2/3/2021 Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole)
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Aug 11, 2021 04:11PM Sadiesservant wrote:

Hi Karen,

I’m sorry to hear of your news. I’m glad your MO is not giving up on Xeloda so quickly however. It seems to me there is a tendency to be a bit over reactive with more frequent scanning that we see these days. As long as you are not suffering with side effects from the progression….

I know how you feel about losing so many lately. I find it hard as well as it seems to have come in waves. So many of those who I leaned on when I was initially diagnosed are gone. It makes it hard to forget the reality of our situations.

Sending hugs.

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Aug 12, 2021 12:54PM - edited Aug 12, 2021 10:19PM by SusaninSF

I've was experiencing a lot of pain in my shoulder, front of my chest, and back. My Interventional Pulmonologist suggested I reduce the frequency of my Pleurx drains. I was doing a drain every day. Tried every three days but my fluid buildup was making it hard to breathe so moved to every other day. Still, I drained close to 600mls after just skipping one day. Trying every day again but my pain has come back making it difficult to sleep. So it's either pain or severe shortness of breath. He also said that it was unlikely that my lung would dry out using the Pleurx. I've been doing it for four months, mostly every day. Now what?

Anyone else who experienced pain while doring Pleurx drains? He said it usually isn't painful.

- Susan

Mets to brain, lung, liver, eye, femur bone. Dx 2000, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 8/31/2000 Lumpectomy: Left, Right; Lymph node removal: Right, Sentinel; Reconstruction (right) Dx 2008, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 3/2/2008 Mastectomy: Right Dx 3/29/2014, Stage IV, metastasized to brain/bone/lungs/other, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 3/31/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/28/2014 External: Brain Chemotherapy 10/30/2014 Xeloda (capecitabine) Radiation Therapy 1/8/2015 External: Bone Radiation Therapy 6/6/2016 External Hormonal Therapy 11/16/2016 Faslodex (fulvestrant) Targeted Therapy 12/21/2016 Ibrance (palbociclib) Radiation Therapy 11/27/2017 External: Brain Hormonal Therapy 8/21/2018 Femara (letrozole) Targeted Therapy 8/21/2018 Piqray (alpelisib) Chemotherapy 4/23/2019 Taxol (paclitaxel) Chemotherapy 6/19/2019 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 10/23/2019 External: Brain Immunotherapy 10/25/2019 Targeted Therapy 2/18/2020 Trodelvy (sacituzumab govitecan-hziy) Dx 3/8/2021, Stage IV, metastasized to liver Hormonal Therapy 3/12/2021 Aromasin (exemestane) Targeted Therapy 3/16/2021 Verzenio Chemotherapy 9/8/2021 Carboplatin (Paraplatin), Gemzar (gemcitabine) Chemotherapy 11/2/2021 Halaven (eribulin)
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Aug 12, 2021 03:15PM Karenfizedbo15 wrote:

Hugs appreciated Sadie!

Surgery 9/6/2007 Lymph node removal: Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2- Dx 2021, Stage IV, metastasized to bone Chemotherapy 2/3/2021 Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole)
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Aug 12, 2021 03:33PM DivineMrsM wrote:

Thinking of you, Karen!

Susan, I'm sorry you're having so much trouble with the drains. Maybe you should call the pulmonologist and let him know things aren't going well and see what he says.


found lump 12-22-10—ilc—er+/pr+/her2—stage iv bone mets—chemo~lumpectomy~radiation~arimidex—March 2019-ibrance/aromasin* —Sept 2019-verzenio* —March 2020-xeloda*
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Aug 12, 2021 03:36PM Sadiesservant wrote:

Hi Susan,

I would suggest your pulmonologist has never had his lung drained if he thinks it's not normally painful.. LOL! Like you, I had a large amount of fluid build up between draining. In my case they were doing it twice a week which resulted in about 800-900 mL being drained each time. My oncologist hoped that we would be able to use the amount of fluid as an assessment of whether the treatment was working but that didn't work out. I had so much irritation after each drain that I am sure it simply stimulated the lung to make more fluid. It sounds like you may be in the same boat. I suspect the problem is that some of us are just more sensitive/attuned to our bodies which means we "feel" things. (My MO was shocked that I have pain with my liver mets as I only have a couple but I knew weeks before the diagnosis that it had spread due to weird jabs..)

There are a couple of tricks that I learned which may help. First, I had the nurses drain the lung SLOWLY. If they went too fast I had a lot of irritation, coughing and pain. If they went reasonably slowly I was able to be much more in control of the draining process and could head things off at the pass before it went too far. (The nurses often wanted to have the bottle on the floor beside my bed thinking if it was below the level of my body it would work better. That's not necessary... it's a vacuum.)

Secondly, don't let them try to drain everything. The PleurX bottles are under a pretty good vacuum (or they don't work) which is damaging to the small capillaries in the lung. I found that if they went slow, I could tell by the rate when the lung was nearly drained (don't let them speed things up at this point - they will try, trust me). At this point I would prepare myself. Once it got to the point it was essentially done I would get a pain that would shoot up my chest in the right lung. That was our cue to STOP. If we followed this procedure I would have a bit of discomfort for an hour or so but it wouldn't last. If they ignored me I would be in discomfort for a good 24 hours which, in your case, would end up being pain all the time.

My lung did eventually dry up after about six months. It wasn't really a gradual reduction of fluid. As I said, I think there was enough irritation that my body just made more fluid to ease the irritation. My body is good at making fluid... However, my personal opinion is that the constant draining acts a bit like pleurodesis - the scarring from the irritation ultimately leads to a reduction in fluid. (One other thing to watch for... when mine stopped draining suddenly there was concern that it might be blocked as there were still pockets of fluid in my lung. The surgeon used a syringe and some saline to see if he could push fluid through. BAD IDEA. It caused an infection and I ended up on the bathroom floor that night with a fever and barely able to function. Oops!) I still have loculated fluid in my right lung four years out but it doesn't cause me any discomfort. I do suspect it makes me more susceptible to respiratory illnesses like pneumonia.

I hope you manage to get this to a point when it's a bit easier on you. I remember what it was like to be gasping to breath just walking 100 yards and that was with only one lung filled with fluid. It was brutal. I can't imagine how anyone manages if both lungs are full! Take care! Pat

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Aug 12, 2021 10:35PM SusaninSF wrote:

Pat,

Thank you SO MUCH for the insightful advice. I'm sure you know that it means so much to get help from someone who has gone through the same troubles.

I was wondering the same thing because I have been stable on Verzenio+Exemestane. I don't want to switch treatments. He did tell me to try to stop before emptying my lungs to try to alleviate the pain. Hopefully, that will help. I've also started coughing over the last few days. Had a chest x-ray that showed an increase in atelectasis since my last CT scan on July 27th. Did you ever get an oxygen supply at home? I worried that I will suddenly get worse and not be able to breathe. This thought is causing me a lot of anxiety so I've been taking Olanzapine at night to help me sleep. Taking Gabapentin for the nerve pain and Aleve for the rest of the pain. I'm a wreck.

Reading about Video-assisted thoracoscopic surgery (VATS). A woman in my support group did this procedure and now her fluid is gone. On the other hand, another woman in the group got rid of her pleural effusion in two months using a Pleurx.

Leaving for Honolulu, my hometown, next week and so sad that I won't be able to swim in the ocean.

Hugs, Susan

Mets to brain, lung, liver, eye, femur bone. Dx 2000, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 8/31/2000 Lumpectomy: Left, Right; Lymph node removal: Right, Sentinel; Reconstruction (right) Dx 2008, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 3/2/2008 Mastectomy: Right Dx 3/29/2014, Stage IV, metastasized to brain/bone/lungs/other, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 3/31/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/28/2014 External: Brain Chemotherapy 10/30/2014 Xeloda (capecitabine) Radiation Therapy 1/8/2015 External: Bone Radiation Therapy 6/6/2016 External Hormonal Therapy 11/16/2016 Faslodex (fulvestrant) Targeted Therapy 12/21/2016 Ibrance (palbociclib) Radiation Therapy 11/27/2017 External: Brain Hormonal Therapy 8/21/2018 Femara (letrozole) Targeted Therapy 8/21/2018 Piqray (alpelisib) Chemotherapy 4/23/2019 Taxol (paclitaxel) Chemotherapy 6/19/2019 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 10/23/2019 External: Brain Immunotherapy 10/25/2019 Targeted Therapy 2/18/2020 Trodelvy (sacituzumab govitecan-hziy) Dx 3/8/2021, Stage IV, metastasized to liver Hormonal Therapy 3/12/2021 Aromasin (exemestane) Targeted Therapy 3/16/2021 Verzenio Chemotherapy 9/8/2021 Carboplatin (Paraplatin), Gemzar (gemcitabine) Chemotherapy 11/2/2021 Halaven (eribulin)
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Aug 13, 2021 06:23AM Karenfizedbo15 wrote:

Good advice from Pat/Sadie. Slow is much better - I had a chest drain in earlier in the year and they drained off 3.5 litres. But I could only manage max 400ml at a time before massive coughing fit. So I overruled the boss who wanted 500ml at a time and told the nurses that’s all I could tolerate. Sometimes you just have to stand your ground - it’s your body and you know best how it copes.

Surgery 9/6/2007 Lymph node removal: Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Dx 4/2018, IDC, Right, Stage IV, metastasized to lungs, 1/17 nodes, ER+/PR+, HER2- Dx 2021, Stage IV, metastasized to bone Chemotherapy 2/3/2021 Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole)
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Aug 13, 2021 09:10AM Sadiesservant wrote:

Karen, when I had the larger volumes taken off (a couple of times before we decided I needed a PleurX - the fluid came back with a vengeance in no time at all) it was really hard on the system. I could manage a couple of litres but after that it got super painful.

Susan, your most welcome. I feel like I lean so much on others that it's nice to be able to help.

I realized after that you must be draining yourself. Here it's done by a homecare nurse but the principle is the same. Go slow and watch for signs that it's getting near the end of the flow. It sounds like the coughing could be from the draining. I also have permanent atelectasis to the bottom of my right lung from the fluid (I essentially have two thirds of my original lung volume). I think that may be common when you have pleural effusion for an extended period. Despite this, I never needed oxygen. It's funny how much we feel the shortness of breath with only one lung involved as people do quite well with only one lung. Go figure...

I'm not familiar with that procedure. I know pleurodesis can be harsh and isn't always successful. I think Bestbird also had success drying up her lung with a PleurX so I think it's worth giving it a try for awhile if it doesn't stop you from trying the other procedure down the road.

Sorry about your dip in the Pacific. But I'll be thinking about you wading in the ocean. I'm not a big traveler but hope to make it back to Hawaii to visit some of the other islands in the next year. At the moment, the US doesn't recognize my COVID vaccination as I had to have Pfizer and then Moderna but they are talking about a possible booster for immunocompromised. Fingers crossed. Safe travels!

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Aug 14, 2021 11:47AM Bestbird wrote:

I'm sorry to hear so many are experiencing pain with draining using the PleurX catheter. I drained the fluid at home, and controlled the velocity by gently pinching the catheter tube to slow it to a more comfortable level. I don't remember draining until completely dry - just when the fluid was nearly gone. When systemic therapy begins to work, draining is no longer needed.

In case it may help, below from my book, "The Insider's Guide to Metastatic Breast cancer" which is also available as a complimentary .pdf, is a list of drainage options. For information about approved treatments by subtype, contending with side effects, cutting edge research and more, please visit https://www.insidersguidembc.com

Pleural effusion, which may accompany lung metastasis, is a buildup of fluid between the layers of tissue that line the lungs and chest cavity. Often the fluid contains cancer cells. Pathology testing should whether the pleural effusion is "exudative" (the fluid has excess protein, blood, or evidence of inflammation or infection) or "transudative" (characterized by a low cell and protein content), based on the chemistry of the fluid. If the fluid transudative it's very unlikely to be malignant, and if it's exudative, malignancy is still a possibility even if malignant cells don't show up when the fluid is tested, so re-testing should be done as warranted, along with any other recommended tests. If the effusion turns out to have malignant cells, testing should be done for ER, PR, and HER2 receptivity, since it is possible that the cancer cells in the effusion may have a different profile than metastasis elsewhere in the body.

For patients who have pleural effusion, there are three methods of draining the fluid to provide relief:

Indwelling (Pleurx or Aspira) Catheter: This is the surgical insertion, under general anesthesia, of a small tube placed temporarily into the pleural space that allows the patient or his/her family member to drain the fluid into a bottle as needed. Patients with an indwelling catheter are fully mobile and are not "attached" to the draining bottle except when draining the fluid. Once there is no more drainage at all, the catheter is removed either in the doctor's office or an outpatient procedure. Overall, indwelling catheters seem to help prevent the fluid from building up again, provided that the patient's systemic treatment is working. The Pleurx catheter works via suction, and the newer gentler model is the Aspira catheter, which is a bit less uncomfortable because uses gravity instead of suction for draining.

Pleurodesis (sometimes referred to as a "talc procedure") is a process in which substances, such as talc, are used to try to get the edge of the lung to stick to the chest wall to decrease the chance of the fluid returning. Although this procedure seems to help prevent the fluid from building up again (provided that systemic treatment is working) it can be painful and usually requires a brief hospital stay. Some patients have reported discomfort months and even years after the procedure. In rare cases, the procedure may fail altogether, rendering it impossible to drain the fluid thereafter because it becomes trapped in a honeycomb of many small pockets (called "loculations"). Of all options for draining malignant pleural effusion, this appears to be the most risk-prone.

Thoracentesis (sometimes referred to as "tapping") is an outpatient procedure that involves placing one needle per required side into the pleural space. Although local anesthesia is administered, this procedure can be uncomfortable and may cause scarring if repeated over time. The procedure also does not hinder fluid buildup again. These tips may make the procedure less uncomfortable: 1) Request a numbing agent before the needle is inserted to feel more comfortable after the procedure. 2) Request that the fluid to be withdrawn slowly in order to avoid low blood pressure or a "fainting" feeling afterwards. 3) Lean forward with a soft pillow supporting your head and upper torso while the draining is underway via your back.

Warning: If a patient is experiencing shortness of breath but the doctor cannot find anything in the lungs that is causing it, the patient should be checked carefully for blood clots as well as for cardiac issues. Either of these issues may cause symptoms that appear to be lung related problems, when in fact they are not. Additionally, a condition called "pneumonitis" (inflammation of the lung), can cause shortness of breath and coughing. Since pneumonitis can be caused by cancer treatments such as chemotherapy and radiation, MBC patients may be particularly susceptible.

Dx 10/6/2011, IDC, Left, Stage IV, ER+/PR+, HER2-
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Sep 2, 2021 11:37AM Novagirl wrote:

Hi everyone. I’m so scared. I have Lymphangitic carcinomatosis. Can anyone help me?

I got 2 years out of ibrance/Letrozole then decided to hold off on Piqray and try Verzenio/Fulvestrant. I got 4 months on this second line therapy. I just saw a pulmonologist who told me to enjoy the time I have not to think about this maybe watch the Tennis/US Open this weekend.

I have innumerable lung nodules on both lungs but they have caused me no trouble and I’ve been asymptomatic. The Lymphangitic carcinomatosis is on my upper right lobe which is where he said the wheezing is coming from. He said my lymph nodes are clear which tells him it traveled via bloodstream. I asked about resection and he said it was pointless.

Can anyone who has had a resection tell me how they decided if you were a candidate? To me, SBRT, surgery, or RFA could work in this one are then I go back to having all these asymptotic tumors.

What type of dr does the surgery and what type of dr does Radiofrequency Ablation?

I had a CT scans two weeks apart and he told me it’s growing. I had a Cerianna PET scan last night but I don’t have the report yet but he did look at the images.

I also don’t know which therapy I should get on next. MO wants fulvestrant Piqray.

I want to get another NGS. I’ve had foundation 1 both times. What are the differences? Should I go with a different lab? I’d like to get a lung biopsy but they said they are too widespread and not big enough.

So sad to read about JFL. She has a young son like me and she is one of the ones I thought could chart her way out of this. I’m sorry for those of you having progression and lung issues.


Currently on first line treatment: Ibrance, Letrozole, Xgeva, Zolodex since 12/22/18 Mets to Lungs and Bones. Originally diagnosed early stage at 31 during the one year postpartum period. Dx 5/30/2013, IDC, Left, 2cm, Stage IIB, Grade 3, 2/12 nodes, ER+/PR+, HER2- (FISH) Surgery 6/27/2013 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 8/30/2013 Herceptin (trastuzumab) Chemotherapy 8/30/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 1/28/2014 Breast, Lymph nodes Hormonal Therapy 3/30/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 6/20/2014 Fareston (toremifene) Dx 12/7/2018, IDC, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Targeted Therapy 12/22/2018 Ibrance (palbociclib) Hormonal Therapy 12/22/2018 Femara (letrozole), Zoladex (goserelin)
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Sep 2, 2021 02:30PM figtree wrote:

novagirl, I had a lobectomy of my right middle lobe at the beginning of my stage 4 diagnosis. At the time I only had a single nodule in my lung and a single hilar node so MO wanted to be aggressive to remove all mets at the time, thus a lobectomy. Your situation sounds different, so I’m not sure when you say a resection, are you thinking a wedge resection or a resection of a lobe? Either surgery is done by a thoracic surgeon. RFA is done by interventional radiologist (IR). Lobectomy is a major major surgery you’ll need at least 4 weeks most likely more time to recover. Wedge resection is easier but it depends on how big the area is. If SBRT is an option, it would be my first choice bc it has least collateral damages. It’s done by a radiation oncologist (RO).Please keep us posted if/when you can about what you choose to do. I’m rooting for you!

Tx history: letrozole+Ibrance 6/2019-11/2020; Xeloda 12/2020-3/2021; Afinitor+Aromasin 3/2021-6/2021; Fulvestrant+Verzenio 6/2021-currently Dx 4/2011, IDC, 3cm, Stage IIIA, Grade 3, 4/8 nodes, ER+/PR+, HER2- Dx 4/2019, IDC, Stage IV, metastasized to bone/lungs/other, ER+/PR+, HER2- Dx 9/2021, IDC, Stage IV, metastasized to bone/liver/lungs/other
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Sep 2, 2021 05:09PM moth wrote:

Novagirl, I don't have Lymphangitic carcinomatosis but just wanted to say I'm sorry you're going through this.

I have read that the issue with resecting this presentation is much less likely to work than a solid tumor. Even though it appears to be localized to one area, I understood that it's possible the whole lung affected and just not detectable in other areas? That's how I was taught it in a pathology class. I think that's why a systemic treatment would be the best option but I think you should obviously gather all the info you can.

Maybe you can get some second opinions? I hope your team comes up with a treatment plan you are confident with.

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, ER+/PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External Hormonal Therapy 12/16/2020 Femara (letrozole) Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone
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Sep 2, 2021 06:23PM Novagirl wrote:

You ladies are the best! This site has the most helpful people.

Figtree, I was thinking about wedge resection or VATS. I did research lobectomy, it is MAJOR surgery. I would do it if they thought it would knock out this LC. Do you regret having it done? That’s great your MO wanted to be aggressive. I didn’t know a thoracic surgeon performed these.

I had SBRT at Hopkins in February this year. They have one machine...I felt like I was pleading my case to have L2 zapped. I was able to get it because when I had radiation right after MBC diagnosis initially-they inadvertently radiated my bowels to get to my lumbar spine. I was so messed up with dehydration and diarrhea for 6 weeks. My bowels have all sorts of issues now because of it...verzenio constipated me so badly it was inducing vomiting. I was thinking I’d have diarrhea like everyone else.

I like your idea of doing SBRT. If Hopkins doesn’t agree I can go somewhere else. I am worried about time. I see my MO tomorrow, I will discuss all of these options with him.

Dee, thank you for the big hugs. I gladly received them. I was coasting along on Ibrance then thought I had finally settled into verzenio and this blind sided me. It’s so rare and it’s hard to find people that have had it.

I read the same case report on the eribulin.

Thank you both! I’ll keep you posted on what MO says and what we do moving forward.

Currently on first line treatment: Ibrance, Letrozole, Xgeva, Zolodex since 12/22/18 Mets to Lungs and Bones. Originally diagnosed early stage at 31 during the one year postpartum period. Dx 5/30/2013, IDC, Left, 2cm, Stage IIB, Grade 3, 2/12 nodes, ER+/PR+, HER2- (FISH) Surgery 6/27/2013 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 8/30/2013 Herceptin (trastuzumab) Chemotherapy 8/30/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 1/28/2014 Breast, Lymph nodes Hormonal Therapy 3/30/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 6/20/2014 Fareston (toremifene) Dx 12/7/2018, IDC, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Targeted Therapy 12/22/2018 Ibrance (palbociclib) Hormonal Therapy 12/22/2018 Femara (letrozole), Zoladex (goserelin)
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Sep 12, 2021 08:47PM SusaninSF wrote:

I had the VATS procedure two Fridays ago. They also decided to replace my Pleurx with a new one in case the VATS procedure didn't work.

Two weeks out it looks like the VATS procedure was "successful" and the linings of my pleura reattached. Happy about that outcome for sure. However, I had a ton of pain after the procedure and have a ton of pain now. I'm weak and can barely get out of bed though lying in bed for so long gives me a backache. So there's no comfortable position for me. I am scheduled to have the new Pleurx removed on Wednesday and hopefully, that is the culprit of the pain. No way to know for sure. I'm on Ibuprofen, Gabapentin and Oxycodone and it barely scratches the surface of the pain. Had an x-ray and bloodwork two days ago and all looked good. Wednesday seems a century away and the removal will likely cause more pain in the short term.

Any ideas or experiences to share? I'm so miserable and sad. Can't stop crying.

Hugs to you all, Susan

Mets to brain, lung, liver, eye, femur bone. Dx 2000, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 8/31/2000 Lumpectomy: Left, Right; Lymph node removal: Right, Sentinel; Reconstruction (right) Dx 2008, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 3/2/2008 Mastectomy: Right Dx 3/29/2014, Stage IV, metastasized to brain/bone/lungs/other, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 3/31/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/28/2014 External: Brain Chemotherapy 10/30/2014 Xeloda (capecitabine) Radiation Therapy 1/8/2015 External: Bone Radiation Therapy 6/6/2016 External Hormonal Therapy 11/16/2016 Faslodex (fulvestrant) Targeted Therapy 12/21/2016 Ibrance (palbociclib) Radiation Therapy 11/27/2017 External: Brain Hormonal Therapy 8/21/2018 Femara (letrozole) Targeted Therapy 8/21/2018 Piqray (alpelisib) Chemotherapy 4/23/2019 Taxol (paclitaxel) Chemotherapy 6/19/2019 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 10/23/2019 External: Brain Immunotherapy 10/25/2019 Targeted Therapy 2/18/2020 Trodelvy (sacituzumab govitecan-hziy) Dx 3/8/2021, Stage IV, metastasized to liver Hormonal Therapy 3/12/2021 Aromasin (exemestane) Targeted Therapy 3/16/2021 Verzenio Chemotherapy 9/8/2021 Carboplatin (Paraplatin), Gemzar (gemcitabine) Chemotherapy 11/2/2021 Halaven (eribulin)
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Sep 12, 2021 10:17PM Sadiesservant wrote:

Susan,

I’m so sorry to hear about your pain. I had no idea you were going through this. Unfortunately I have no suggestions. I recall the pain from them over draining my lung like it was yesterday and can only imagine how hard it is for you to cope with. Sending virtual hugs.

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Sep 13, 2021 06:09AM BevJen wrote:

Susan,

No advice to offer but just wanted to say that I'm thinking of you. So sorry for your pain, and I hope the procedure on Wednesday helps to clear it up. Hang in there. You are a fighter for sure.

Microwave Ablations,Liver 3x ;Radiation Therapy to Femur (Both) April 2021; total hip replacement (R) and placement of rod (L) to stabilize femur both sides; immunotherapy (single agent - keytruda) Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/4/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole) Radiation Therapy Immunotherapy
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Sep 13, 2021 06:54AM Tina2 wrote:

Susan,

Intractable pain is a horror. I join you in wishing for Wednesday's speedy arrival.

By your side,

Tina


Stage I, mastectomy, 1985.Stage I, mastectomy, 1995. Stage IV, lung mets treated with Faslodex 2011-/2018. Treatment hiatus 9/2018-3/2020. Ibrance and Faslodex 3/2020. Faslodex only 11/20. Dx Stage IV, mets, ER+/PR+
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Sep 13, 2021 09:05AM moth wrote:

Susan, I'm glad your VATS procedure was successful but so sorry to hear of your pain.

Are you home or in hospital? I'm wondering if you can get a referral to anesthesia for a regional nerve block while this heals. They're often placed during and post surgery and they reduce the requirement for opiates. They're being increasingly used here.
Or maybe an urgent referral to palliative medicine - they're really the best at managing pain. Your mobility is super important so one way to think about this is that you need to get pain managed so you can get up because not being up is extremely dangerous.

I hope your team can put something together to help you asap! Meanwhile sending lots of hugs

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, ER+/PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External Hormonal Therapy 12/16/2020 Femara (letrozole) Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone
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Sep 13, 2021 09:51AM KarPC wrote:

Oh Susan, it sounds horrible and I am so sorry you are going thru this. I don't have any knowledge to share but I am thinking of you and sending you an air hug.

​May 2021 lung nodule flipped from ER+ to triple negative. Liver tumor may still be ER+ Dx 4/2016, IDC, Both breasts, 2cm, Stage IIA, Grade 3, 0/14 nodes, ER+/PR-, HER2- Surgery 5/17/2016 Lymph node removal: Sentinel; Mastectomy: Left, Right; Reconstruction (left); Reconstruction (right) Chemotherapy 6/10/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 10/1/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 2/1/2018, IDC, <1cm, Stage IV, metastasized to liver/lungs, Grade 3, ER+/PR-, HER2- Radiation Therapy 2/2/2018 External: Liver Targeted Therapy 2/16/2018 Ibrance (palbociclib) Hormonal Therapy 2/17/2018 Faslodex (fulvestrant), Femara (letrozole), Zoladex (goserelin) Chemotherapy 2/19/2020 Xeloda (capecitabine) Targeted Therapy 10/14/2020 Afinitor (everolimus) Targeted Therapy 6/1/2021 Piqray (alpelisib)
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Sep 13, 2021 03:18PM figtree wrote:

Susan, I’m so sorry you are in so much pain. I totally agree with Moth at a nerve block is the way to go. When I had VATS to remove a lobe of my lung, the surgeon did nerve block along the nerves on my ribs during the surgery and it helped A Lot. But maybe your pain is caused/exacerbated by the new pleurx placement. If that’s the case I wish Wednesday is already here for you. Sending calming thoughts to you...

Tx history: letrozole+Ibrance 6/2019-11/2020; Xeloda 12/2020-3/2021; Afinitor+Aromasin 3/2021-6/2021; Fulvestrant+Verzenio 6/2021-currently Dx 4/2011, IDC, 3cm, Stage IIIA, Grade 3, 4/8 nodes, ER+/PR+, HER2- Dx 4/2019, IDC, Stage IV, metastasized to bone/lungs/other, ER+/PR+, HER2- Dx 9/2021, IDC, Stage IV, metastasized to bone/liver/lungs/other
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Sep 14, 2021 08:19PM SusaninSF wrote:

You are all so wonderful and kind to get back to me with comforting words. I am so grateful to be on this board. I had one friend in my support group who was dealing with a Pleurx but she invoked her right to die last week. She was only 32 and such a kind and strong woman. Her death has made all of this harder to take.

I will ask about a nerve block if the pain doesn't subside after the Pleurx removal. Great idea. How long does it last? I spoke to my Palliative Care doctor today but he didn't mention a nerve block. He did clarify that I need to take Gabapentin regularly but can take Oxycodone as needed. No one explained any of this to me when I was prescribed the drugs. Spent most of today at the Cancer Acute Center at UCSF getting tests and a brain MRI done. Last Friday my Neutrophils (usually around 1.5. Went up to 8.35) and WBC (usually low around 2.9. Went up to 9.2) jumped so I was worried I had some kind of infection. I also have a droopy right eye. They were really worried about the droopy eye but I was thinking it just needed a warm compress. Brain MRI looked great so they are less worried about that.

Tomorrow is already Wednesday so I'm very hopeful but at the same time worried about being disappointed.

figtree, The pain of removing a lobe has to be many magnitudes worse than what I'm experiencing. So glad the nerve blockers helped.

Big hugs and love, Susan


Mets to brain, lung, liver, eye, femur bone. Dx 2000, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 8/31/2000 Lumpectomy: Left, Right; Lymph node removal: Right, Sentinel; Reconstruction (right) Dx 2008, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 3/2/2008 Mastectomy: Right Dx 3/29/2014, Stage IV, metastasized to brain/bone/lungs/other, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 3/31/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/28/2014 External: Brain Chemotherapy 10/30/2014 Xeloda (capecitabine) Radiation Therapy 1/8/2015 External: Bone Radiation Therapy 6/6/2016 External Hormonal Therapy 11/16/2016 Faslodex (fulvestrant) Targeted Therapy 12/21/2016 Ibrance (palbociclib) Radiation Therapy 11/27/2017 External: Brain Hormonal Therapy 8/21/2018 Femara (letrozole) Targeted Therapy 8/21/2018 Piqray (alpelisib) Chemotherapy 4/23/2019 Taxol (paclitaxel) Chemotherapy 6/19/2019 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 10/23/2019 External: Brain Immunotherapy 10/25/2019 Targeted Therapy 2/18/2020 Trodelvy (sacituzumab govitecan-hziy) Dx 3/8/2021, Stage IV, metastasized to liver Hormonal Therapy 3/12/2021 Aromasin (exemestane) Targeted Therapy 3/16/2021 Verzenio Chemotherapy 9/8/2021 Carboplatin (Paraplatin), Gemzar (gemcitabine) Chemotherapy 11/2/2021 Halaven (eribulin)
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Sep 27, 2021 08:54AM GR4C1E wrote:

Has this ever happened to you?

My MO's office just called and said that due to shortages they are unable to get their shipment of Abraxane and could I come in earlier this week to discuss alternative treatment options.

What the........?

Dx 9/2/2011, IDC, Left, 2cm, Stage IA, Grade 3, 0/2 nodes, ER-/PR-, HER2- Surgery 10/25/2011 Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left); Reconstruction (right) Chemotherapy 11/23/2011 AC + T (Taxotere) Dx 1/4/2021, IDC, Right, Stage IV, metastasized to lungs, ER-/PR-, HER2- Chemotherapy 1/20/2021 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 7/20/2021 Gemzar (gemcitabine) Chemotherapy 9/16/2021 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 10/7/2021 Taxotere (docetaxel)
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Sep 27, 2021 09:07AM Sadiesservant wrote:

Wow GR4C1E. That would really make me lose my #%&%. While I understand these things happen, it's worrisome as there are some considerations regarding timing and sequencing of treatments. As an example, I just had a discussion with my MO on Friday about which drug to move to and he has me on Navelbine. I think his preference would have been Halaven but he said we can do Navelbine then Halaven but not the other way around. Not really clear why...

I would suggest you ask them if this will in any way negatively impact access to any drugs going forward. If not, it's likely okay but I would want to be sure first. Sorry you are having to face this.

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)
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Sep 27, 2021 09:35AM GR4C1E wrote:

I'm stuck in the whole cancer panic cycle right now, and the self destructive anxiety loop playing in my brain keeps asking me "how bad is this gonna get?" I'm trying to shut it off but having internet access at work is sending me down the research rabbit hole! AAARRGH!!

PLUS, my appointment to discuss my "options" isn't until Wednesday, so that just makes it worse!

I just have to keep reminding myself that there ARE options and there are other taxanes out there.

Dx 9/2/2011, IDC, Left, 2cm, Stage IA, Grade 3, 0/2 nodes, ER-/PR-, HER2- Surgery 10/25/2011 Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left); Reconstruction (right) Chemotherapy 11/23/2011 AC + T (Taxotere) Dx 1/4/2021, IDC, Right, Stage IV, metastasized to lungs, ER-/PR-, HER2- Chemotherapy 1/20/2021 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 7/20/2021 Gemzar (gemcitabine) Chemotherapy 9/16/2021 Abraxane (albumin-bound or nab-paclitaxel) Chemotherapy 10/7/2021 Taxotere (docetaxel)
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Sep 27, 2021 09:55AM Sadiesservant wrote:

Sorry. I don't think I was particularly helpful! You're right, there are other taxanes. I started out on Taxol which was very tolerable. Sending hugs...

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine)

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