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Topic: what do hot spots mean?

Forum: Stage IV and Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Jan 22, 2012 12:31AM

goldie123 wrote:

 i was dx with stage 4,  9 months ago and have been on faslodex and xgeva since..  last month i had a pet scan which showed there was no change but the doctor did say she saw some hots spots. does this mean that there are areas that look like they are getting worse? my tms have been going up for the last 3 months so i assume the faslodex may have to be changed. i have an appointment this week so i'd like to br prepared

Dx 7/2/2006, LCIS, 6cm+, Stage IV, Grade 2, 26/35 nodes, ER+/PR+, HER2-
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Jan 22, 2012 01:29AM usafmom wrote:

Hot spots..when referring to a petscan means the area showed metabolic uptake. That means that area was more active which means it may be cancerous. The only way you will know for sure is from a biopsy. But since we have active cancer already they assume these areas would be where the cancer has spread. But a petscan can give false positive readings too.

I hope that makes sense to you..I've had several petscans in the last few months with lots of hotspots. So I can understand your frustration. You will be in my thoughts and prayers.


Hugs Kimber Dx 10/31/2007, IDC, 4cm, Stage IV, Grade 3, 12/40 nodes, mets, ER+/PR+, HER2+
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Jan 22, 2012 01:32AM usafmom wrote:

I should have added that if it showed no change from maybe a MRI or ct scan you had previously that is good news. The petscan will just help confirm malignancy from benign or inflammation.

Hugs Kimber Dx 10/31/2007, IDC, 4cm, Stage IV, Grade 3, 12/40 nodes, mets, ER+/PR+, HER2+
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Jan 22, 2012 10:41AM mari55 wrote:

Kimber's explanation is right on.  I would add that even though I am stable I continue to have some active or "hot" spots in my bones so unless these are new spots you may not need to change treatment.  I wish you the best


DCIS 1999, R mastectomy. Mets to spine, sternum,ribs,and femurs Jan. 2010 and new primary on left, DCIS, Dec. 2009. I am not afraid of dying, I am afraid of not living Dx 1/11/2010, Stage IV, mets, ER+/PR-, HER2-
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Jan 22, 2012 12:52PM nancyh wrote:

Hey Goldie, 

Sorry to hear about the hot spots, the explanation above is correct. PET scans tell how active the cancer is, so between your scan results and TM's going up it might be time to change treatment.  Good luck with your appointment and keep us posted. 

Stage 4 in 2009, mets to liver, lungs, bones, and brain. Dx 8/12/2002, IDC, 1cm, Stage IIB, 3/12 nodes, ER+/PR+, HER2- Chemotherapy 10/1/2002 AC Chemotherapy 1/1/2003 Taxol (paclitaxel) Hormonal Therapy 5/1/2003 Dx 4/2/2007, IDC, 1cm, Stage II, ER+/PR+, HER2- Chemotherapy 6/1/2007 CMF Dx 9/1/2009, IDC, Stage IV, metastasized to brain/bone/liver/lungs, mets, ER+/PR+, HER2- Targeted Therapy 9/1/2009 Avastin (bevacizumab) Chemotherapy 9/1/2009 Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy 6/1/2010 Femara (letrozole) Chemotherapy 9/1/2011 Xeloda (capecitabine) Hormonal Therapy 1/1/2012 Faslodex (fulvestrant) Chemotherapy 6/1/2012 Navelbine (vinorelbine) Chemotherapy 5/1/2013 Gemzar (gemcitabine) Hormonal Therapy 6/1/2013 Aromasin (exemestane) Targeted Therapy 8/1/2013 Afinitor (everolimus) Chemotherapy 10/28/2013 Halaven (eribulin) Chemotherapy 11/12/2014 Taxotere (docetaxel) Chemotherapy 10/1/2015 Adriamycin (doxorubicin) Targeted Therapy Ibrance (palbociclib)

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