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May 3, 2017 05:16AM
Xeloda crosses the blood brain barrier and there are a few of us with LM that have had success with Xeloda, and yet a lot of others have not. And with some others, they have had to have different treatment which worked for them, so we are all just so very different.
Like Breast Cancer has so many different types of breast cancer and different grades and stages, I think that LM also is different for everyone else as well with what type or what grade it is and where it is located. That seems to be my only answer, but I am only guessing. I am not sure exactly where the Leptomeninges are. I know that they are in the lining surrounding the brain, but which lining? there are probably two or three different linings surrounding the brain, and then it goes along the brain stem and also in the spinal fluid. So I think that where you have your LM plays an important part but also the grade etc. Mine was in the right parietal area of my brain. I had another one in the lining above my left eye which was not LM and another met in the lining right at the top of the brain at the front that separates the two halves if that makes sense.
Just to put your mind in a positive frame of mind, I was diagnosed with LM in November 2012 and my prognosis then was dismal, with prognosis of weeks maybe months, but I was put onto Xeloda straight away. I also had mets in the liver and lungs as well as bones at at the same time. Fast forward 9 weeks later and CT scan and MRI scan showed regression in the organs but not the bones and I was NED in all the organs about 15 months later.
I hope that Xeloda keeps working and hopefully that it was not LM, however if it is then at least Xeloda may keep it at bay.
"Don't give in to the disease" Dr Phil McGraw
12/13/2006, IBC, 3cm, Stage IIIB, Grade 2, 11/22 nodes, ER+/PR+, HER2-
12/28/2006 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil), Taxotere (docetaxel)
5/20/2007 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right
11/17/2012, IBC, Right, 3cm, Stage IV, metastasized to brain/bone/liver/lungs, Grade 2, 11/22 nodes, ER+/PR+, HER2-
11/27/2012 Xeloda (capecitabine)