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Topic: How are people with liver mets doing?

Forum: Stage IV/Metastatic Breast Cancer ONLY —

Please respect that this forum is for members with stage IV/metastatic breast cancer only. There is a separate forum for caregivers and friends: Caring for Someone with Stage 4 or Mets.

Posted on: Aug 16, 2013 04:02PM

blondie1 wrote:

I continue to be very scared once I found my liver mets progressed after having to go off doxil. I am hoping to find some support in alleviating my deep seated fears by hearing other stories of people living and dealing with liver mets. My onc says I have such a petite frame (105) that an enlarged liver will definitely cause me some pain until chemo takes care of it.

How are others doing and getting through this with a positive attitude?

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Jul 23, 2021 06:23AM leftfootforward wrote:

Saulius- beautiful photo. Thanks for sharing. Lymph nodes not changing and docs who aren’t concerned is wonderful. Celebrate your wife’s and your well earned victory.

BLmike- my thoughts are with you.

Dx 12/13/2010, IDC, 3cm, Stage IIIA, Grade 2, 1/16 nodes, ER-/PR-, HER2+ Dx 12/4/2012, IDC, Stage IV, 0/0 nodes, ER-/PR-, HER2+
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Jul 23, 2021 06:38AM lafsunshine wrote:

Dear BLMike,

My heart aches for your dear wife and you. You are both in my prayers

7/2021- Keytruda + Abraxane Dx 1/2018, IDC, Left, 1cm, Stage IB, Grade 2, 0/2 nodes, ER+, HER2- Dx 7/2020, IDC, Stage IV, metastasized to bone/liver/other, ER+/PR-, HER2- Radiation Therapy Whole-breast: Breast Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Arimidex (anastrozole) Surgery Lumpectomy: Left; Lymph node removal: Sentinel, Underarm/Axillary Hormonal Therapy Faslodex (fulvestrant)
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Jul 23, 2021 06:48AM B-A-P wrote:

Oh BLMIke, So sorry to hear this . I know how much she means to you. Thank you for being a presence here and sharing her story.

Dx 8/17/2018, IDC, Left, Stage IV, metastasized to liver, ER+/PR+, HER2- (FISH) Chemotherapy 9/17/2018 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Surgery 2/26/2019 Mastectomy: Left, Right Radiation Therapy 4/28/2019 Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy 10/7/2021 Ibrance (palbociclib) Dx IDC, Stage IV, metastasized to liver, ER+/PR-, HER2- (FISH) Hormonal Therapy Femara (letrozole) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Prophylactic ovary removal Chemotherapy Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Faslodex (fulvestrant)
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Jul 23, 2021 07:53AM lafsunshine wrote:

Saulius - what a great photo of your wife and you, thanks for sharing.

B-A-P - sending good vibes for a good outcome on your CT today.

Kattysmith - thoughts and prayers for you

7/2021- Keytruda + Abraxane Dx 1/2018, IDC, Left, 1cm, Stage IB, Grade 2, 0/2 nodes, ER+, HER2- Dx 7/2020, IDC, Stage IV, metastasized to bone/liver/other, ER+/PR-, HER2- Radiation Therapy Whole-breast: Breast Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Arimidex (anastrozole) Surgery Lumpectomy: Left; Lymph node removal: Sentinel, Underarm/Axillary Hormonal Therapy Faslodex (fulvestrant)
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Jul 23, 2021 08:32AM Husband11 wrote:

BLMike, I am so sorry to hear about your wife's worsening condition. You are both in my prayers.

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Jul 23, 2021 08:47AM Grannax2 wrote:

LFF I remember feeling exactly like that when my HGB went down to 5.2. Yep hospital and two units of blood. That was a almost two years ago but I won’t forget to listen to my body.

BLMike. I’m so sad to hear this news about your wife. Prayers for both of you.

Kattysmith. It’s good to hear from a fellow Texan. But, of course, I don’t like to hear that you got the talk. We all know we’ll get the talk at some point but I dread it. I’m too close for comfort. Nothing is working for me. Chemos are fail, fail, fail. I’m taking a three month break from any TX so that I can make some good memories with my family. My grandson is 9. I may consider a clinical trial in the fall but I don’t think I will do anymore chemo.

Wish we didn’t have such tough decisions to make

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Jul 23, 2021 09:35AM Sadiesservant wrote:

BLMike, I’m so sorry to hear about Polly. While we all know we will get to that point eventually it’s impossible to be prepared. You are both in my thoughts and prayers.

Kattysmith and Grannax, I’m also sorry you are reaching such a difficult place in your treatment decisions. Sending virtual hugs to you both.

I’m behind with the thread but my heart goes out to all of those struggling right now.
Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine) Chemotherapy 10/8/2021 Navelbine (vinorelbine) Chemotherapy 1/7/2022 Halaven (eribulin)
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Jul 23, 2021 10:16AM BevJen wrote:

cross posting with local liver procedures...

Has anyone had local liver treatments to liver mets at Memorial Sloan Kettering? If so, what kind of treatment(s) have you had?

After my hyper explosion of mets from my short period on immunotherapy, my interventional radiologist at Hopkins said he wouldn't do anything else local with my liver. I am currently on xeloda and neratinib. Bone mets are stable but the issue is the liver mets.

I have watched for about two years the expansion of material on the MSK site about liver treatments, especially mets, and it seems that they are talking about a lot of options in a lot of situations. On a short video that I watched, they were talking about how many procedures they do in a year, and how it may be best to go to a high volume center for these types of treatments.

Thanks for any info you can provide. I've had 3 microwave ablations.

Microwave Ablations,Liver 3x ;Radiation Therapy to Femur (Both) April 2021; total hip replacement (R) and placement of rod (L) to stabilize femur both sides; immunotherapy (single agent - keytruda) Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/5/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Keytruda (pembrolizumab) Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole) Radiation Therapy
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Jul 23, 2021 11:51AM moth wrote:

BLMike & Polly, oh damn, I'm sorry to hear your news.

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External: Chest wall Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone
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Jul 23, 2021 12:13PM - edited Jul 23, 2021 12:18PM by NicoleRod

BLMike so sorry to hear this!!!!!!!! UGHHHHHH I am so angry for you both!!!!!! There are no other words.... except prayed for you both.


Saulius you both look so great and so healthy. I pray we all soon get drugs like HER2+ has so we all have the same chances that you both are getting its so great for you both!!! I am so happy you both look...so happy!!!

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Jul 23, 2021 02:02PM Kabuki wrote:

I just received the results of the pet scan and it’s not good. My liver is covered with tumors ranging in size from 3.5 cm to 10 cm that involves most of segments 5 and 6.

They is a lesion on the right iliac bone that measures 1.6 cm.


There is an enlarged hyper metabolic portacaval lymph node that measures 2.1 cm.


it’s just too widespread and too large. I can’t see how treatment can really do anything at this point.

I was first told that it didn’t look like cancer, than it was 3 CM and than the cat scan read 7 cm and now this. I can’t deal with this

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 02:30PM Husband11 wrote:

Kabuki,

With the right treatment it is possible to greatly knock it back down. It's just as important how you respond to treatment, as the starting point. Treatment type will depend on the characteristics of the cancer. Have they done a biopsy and given you back results on hormone receptor status and HER2 status?

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Jul 23, 2021 02:39PM Kabuki wrote:

Husband11,

They did do a liver biopsy. ER+ PR- H2 waiting fish test.


Im on Verzenio 150mg and start Faslodex injections on Monday.

My oncologist is sending me to UCSF to see if there are any studies but it’s so overwhelming right now

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 03:21PM - edited Jul 23, 2021 03:23PM by Rosie24

BLMike, I too am very sorry to hear of Polly's recent downturn. It's hard to read that one of our own is at the point of hospice. Sending you both warm thoughts and a wish that you can feel the support coming from this group.

Thinking of Grannax2, Kattysmith, Nicole, and Kabuki. Each of you have different things to get through, and I hope each of you comes out in a good place.

Saulius, It's so nice that you posted that pic for us to have a real image of you as we read your posts. You both look fabulous!


Dx 1/23/2019, DCIS/IDC, Left, 3cm, Stage IV, metastasized to liver, Grade 2, ER+/PR-, HER2- (FISH) Hormonal Therapy 1/24/2019 Femara (letrozole) Targeted Therapy 1/24/2019 Ibrance (palbociclib) Surgery 12/3/2019 Lumpectomy: Left Surgery 12/3/2019 Lymph node removal: Sentinel Dx 1/6/2022, IDC, Stage IV, metastasized to liver, ER-/PR-, HER2- Radiation Therapy Whole-breast
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Jul 23, 2021 03:58PM leftfootforward wrote:

kabuki- UCSF is where I went for a clinical trial. They were great and knew their stuff. They will be a good source of information and hopefully treatment.

At one point I had to switch to weekly taxol treatments to try and control niumerpus liver tumors. I was on taxol foe 2 years. It worked wonders when to get rid of my liver spots.

I wish you wel

Dx 12/13/2010, IDC, 3cm, Stage IIIA, Grade 2, 1/16 nodes, ER-/PR-, HER2+ Dx 12/4/2012, IDC, Stage IV, 0/0 nodes, ER-/PR-, HER2+
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Jul 23, 2021 04:12PM Kabuki wrote:

leftffotforwarward,

I had heard that Hope Rugo is the best breast cancer specialist but the oncologist is sending me to Michele Milisko.

Does anybody have experience with either of them

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 04:16PM D37 wrote:

BLMike, I am so sorry, my thoughts and prayers are with you and your wife.

Kabuki, When I was diagnosed with liver mets last year the pet scan results said: “liver engulfed in metastatic tumors”. I had ascites and was in a lot of pain. Taxol worked wonders for me.

Dx 7/2020, ER+/PR+, HER2+ Hormonal Therapy 8/11/2020 Chemotherapy Taxol (paclitaxel)
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Jul 23, 2021 04:29PM Kabuki wrote:

Thank you D37 and leftfoot for the Taxol reports. Maybe that’s what I should be on

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 06:09PM - edited Jul 24, 2021 03:21AM by SandiBeach57

Kabuki

1st Dx, widespread liver mets, adriamycin, cytoxan for 3 months then switched to Letrozole, Ibrance, 3+years

1st Progression, widespread liver mets, Xeloda, 15 months

2nd Progression, widespread ( diffuse with tumors from 3 cm to 10 cm), Weekly Taxol, just started, we will see!

So many options Kabuki. Your MO will find the right combo.

Wear your jewelry. See my Biography for treatment history.
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Jul 23, 2021 06:28PM Kabuki wrote:

Sandibeach,


I hope the taxol works for you. We have identical size of liver mets

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 07:24PM SeeQ wrote:

Kabuki - liver mets only , but 11.8 cm (on MRI, larger on PET-CT), 4. 8 cm + numerous other tumors. NED within 8 months on Verzenio + Anastrazole. Hang in there.

Diagnosed de novo Stage IV; large liver mets; small breast tumor Dx 6/2/2020, IDC, 6cm+, Stage IV, metastasized to liver, ER+/PR+, HER2- (IHC) Hormonal Therapy 7/2/2020 Arimidex (anastrozole) Targeted Therapy 7/9/2020 Verzenio
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Jul 23, 2021 07:45PM Kabuki wrote:

Conratulations SeeQ! You give me hope. I read that ER and PR+ have a very good response to treatment. ER + only is more aggressive and resistant to treatment

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 23, 2021 10:07PM NinaCA wrote:

Mermaid007- I was on letrozole alone for 14 years- I was immediately switched from Tamoxifen to letrozole after finding a liver met (3 years after initial BC diagnosis). After 6 months it disappeared just as I was planning on an ablation, and stayed gone for 14 years. This was the first drug I took once I was metastatic ( I had IV drugs for my initial diagnosis for Stage 3-AC and Taxatere). I think I was highly ER+ and the AI kept my estrogen level low so as not to feed my liver tumor. I don't know anyone where the drug worked this well.

Dx 2/1998, IDC, Left, 5cm, Stage IIIA, ER+/PR+, HER2- Dx 1/2003, Stage IV, metastasized to liver, ER+/PR+, HER2- Dx 7/2015, Stage IV, metastasized to liver, ER+/PR+, HER2- (FISH) Dx 1/2020, ILC/IDC, Stage IV, metastasized to liver/other, ER+, HER2- (FISH) Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib) Chemotherapy Xeloda (capecitabine) Surgery Surgery
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Jul 24, 2021 03:56AM Mermaid007 wrote:

Nina,

Thank you for your reply. I am highly estrogen positive too. I'm not sure if it's the same in the USA but in the Uk we use a test called the Allred score. The highest number for estrogen is 8 which is what I am, although negative for PR and HER. My primary was in 1999 but found in my bones 16 years later ! Then spread to liver. Treatment has been Exemestane then Verzinio/Faslodex now Xeloda. So I was encouraged to hear that Letrezole can also work on liver mets.

You also mentioned the high dose of Xeloda that I was started on. How do your MO's decide on dosage? Here they use BSA so it's based on height and weight. Because I am 5'6" and quite well built ( US size 12) my dose was 4300 per day!!! I was so ill and managed to get it reduced to 3000 per day. It seems a crazy way to determine dosage.

I'm glad Xeloda is working well for you, you are an inspiration to me.

Take Care

Debs xx

Debs
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Jul 24, 2021 04:28AM NicoleRod wrote:

Kabuki I think you are right about those that are ER+ but PR- HER2- are more resistant to treatments. That is what I am and I have not gotten a treatment to work more than 4 months..I just finished 5th line.

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Jul 24, 2021 05:19AM Kattysmith wrote:

Grannax, it's good to hear from you and I think taking a few months off to spend time with family and friends is a great idea. I'm focusing on that this summer as well!

Dee, thank you for the link to the clinical triaI . I know we spoke about it when you contacted me privately a while back and I appreciate it. I like my oncologist but he is very old school and has pooh-poohed any suggestion that my neuroendocrine features should be factored in to any treatment decisions, so he wouldn't order the tests that you had recommended based on your experience. Depending on how doxil works out I will definitely keep this in my pocket although I do have serious financial limitations etc etc etc.

He did say that at this point my liver is only 5% compromised. My blood work has been pretty much all within normal range most of the time but I did notice that my last blood work showed a big spike in my ALT... or maybe it was AST, I need to go back and look it up.

First diagnosed borderline Stage 2 IDC, left breast in 2003. No problems until a surprise (!) Stage IV recurrence in 2015! In addition to treatments listed below, I started monthly injections of Xgeva for bone support in July 2016. Dx 10/23/2015, Left, Stage IV, metastasized to other, Grade 3, 0/3 nodes, ER+, HER2- Chemotherapy 11/3/2015 AC Hormonal Therapy 2/4/2016 Femara (letrozole) Targeted Therapy 2/4/2016 Ibrance (palbociclib) Immunotherapy 12/22/2018 Hormonal Therapy Faslodex (fulvestrant)
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Jul 24, 2021 09:46AM Kabuki wrote:

NicholeRod, How frustrating for you. I’m still waiting for the FISH test for Herception. The oncologist said even if it comes back negative he may recommend Herception. He said in some cases they are seeing some success with the drug.

I’ll let you know what he says the next time I see him. I was PR+ with the original breast cancer do the histology is changing to adapt. Not a good thing

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 24, 2021 10:34AM Kabuki wrote:

NicholeRod,

This is the study that I found

https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1121-4


Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)
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Jul 24, 2021 10:34AM NicoleRod wrote:

Kabuki...wait...I am confused what was your original... ER+ PR+ HER2-??? My originial BC Stage 0 was ER+ PR+ HER2-...recurrence Stage 4 was ER+ PR- HER2-....and my HER2- (at that time 2 years ago) was 0% for HER2+..... I don't expect that has changed except to go to Triple Negative....

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Jul 24, 2021 10:46AM Kabuki wrote:

NicholeRod,


My primary 11 years ago was ER+, PR+, HER-.

The liver biopsy was ER+, PR-, and waiting on FiSH for HER2 status. It looks like HER2- but the oncologist said that if a small amount is shown they are treating with Herceptin

Dx 6/2009, IDC, Left, 6cm+, Stage IIIC, Grade 2, 3/7 nodes, ER+/PR+, HER2- (IHC) Dx 7/2021, IDC, Left, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- (IHC) Targeted Therapy Verzenio Radiation Therapy Surgery Mastectomy: Left; Reconstruction (left): DIEP flap Chemotherapy AC + T (Taxol)

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