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Topic: How are people with liver mets doing?

Forum: Stage IV/Metastatic Breast Cancer ONLY —

Please respect that this forum is for members with stage IV/metastatic breast cancer only. There is a separate forum for caregivers and friends: Caring for Someone with Stage 4 or Mets.

Posted on: Aug 16, 2013 07:02PM

blondie1 wrote:

I continue to be very scared once I found my liver mets progressed after having to go off doxil. I am hoping to find some support in alleviating my deep seated fears by hearing other stories of people living and dealing with liver mets. My onc says I have such a petite frame (105) that an enlarged liver will definitely cause me some pain until chemo takes care of it.

How are others doing and getting through this with a positive attitude?

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Nov 29, 2021 07:43PM - edited Nov 29, 2021 07:57PM by Moveforward

This Post was deleted by Moveforward.
Targeted Therapy 5/16/2020 Ibrance (palbociclib)
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Nov 29, 2021 07:48PM SusaninSF wrote:

Thanks for the tip, Moveforward. I have dry mouth all day long. Biotin never helped me either.

Mets to brain, lung, liver, eye, femur bone. 1/6/22 started on ARX788 trial. Dx 2000, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 8/31/2000 Lumpectomy: Left, Right; Lymph node removal: Right, Sentinel; Reconstruction (right) Dx 2008, DCIS, <1cm, Stage 0, Grade 3, 0/2 nodes, ER+/PR+, HER2- Surgery 3/2/2008 Mastectomy: Right Dx 3/29/2014, Stage IV, metastasized to brain/bone/lungs/other, mets, ER+/PR-, HER2- (FISH) Hormonal Therapy 3/31/2014 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 4/28/2014 External: Brain Chemotherapy 10/30/2014 Xeloda (capecitabine) Radiation Therapy 1/8/2015 External: Bone Radiation Therapy 6/6/2016 External Hormonal Therapy 11/16/2016 Faslodex (fulvestrant) Targeted Therapy 12/21/2016 Ibrance (palbociclib) Radiation Therapy 11/27/2017 External: Brain Hormonal Therapy 8/21/2018 Femara (letrozole) Targeted Therapy 8/21/2018 Piqray (alpelisib) Chemotherapy 4/23/2019 Taxol (paclitaxel) Chemotherapy 6/19/2019 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 10/23/2019 External: Brain Immunotherapy 10/25/2019 Targeted Therapy 2/18/2020 Trodelvy (sacituzumab govitecan-hziy) Dx 3/8/2021, Stage IV, metastasized to liver Hormonal Therapy 3/12/2021 Aromasin (exemestane) Targeted Therapy 3/16/2021 Verzenio Chemotherapy 9/8/2021 Carboplatin (Paraplatin), Gemzar (gemcitabine) Chemotherapy 11/2/2021 Halaven (eribulin) Radiation Therapy 12/21/2021 External: Bone Targeted Therapy 1/6/2022
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Nov 30, 2021 01:59AM BSandra wrote:

Dear Nicole, congratulations, I think it is a very good scan and sign. "Reduction", "decrease" are magical words. What about that unstable lesion, is it a real or pseudo increase (as it is difficult to understand because of Y90 treatment)? Saulius

Since May'21:NED. Mar'21:axilla LN surgery. Sep'19-Mar'21:NED. Feb'19:recurrence, left breast,IBC. May'18-Feb'19:NED. Jun'18:DC/CIK. Aug'17:stage IV de novo at age 33. Dx 8/4/2017, IDC, Left, 6cm+, Stage IV, metastasized to liver, Grade 2, ER-/PR-, HER2+ (IHC) Chemotherapy 8/27/2017 Taxotere (docetaxel) Targeted Therapy 8/28/2017 Herceptin (trastuzumab) Targeted Therapy 8/28/2017 Perjeta (pertuzumab) Chemotherapy 3/12/2019 Taxotere (docetaxel) Surgery 7/22/2019 Mastectomy: Left Radiation Therapy 9/9/2019 Whole-breast: Lymph nodes, Chest wall Surgery 4/15/2021 Lymph node removal: Underarm/Axillary Radiation Therapy 12/13/2021 3DCRT: Lymph nodes
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Nov 30, 2021 01:13PM - edited Nov 30, 2021 01:27PM by NicoleRod

I'm I'm hospital severe pain in brain. Did a CT scan they saw somethjng..looks like a brain met.....waiting for MRi all I know is is its on the right in the Front??? FINDINGS: There is an ill-defined area of hypodensity in the subcortical

white matter of the right frontal lobe, best identified on images

#14-16. It measures approximately 1.8 cm in size. There is no mass

effect.

I'm freaking out

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Nov 30, 2021 01:18PM moth wrote:

oh crap, NIcole. Sending you gentle hugs

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External: Chest wall Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone
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Nov 30, 2021 01:32PM Husband11 wrote:

Oh Nicole, that is terrible. We are with you. We never get tired of giving out hugs and support here.

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Nov 30, 2021 01:39PM candy-678 wrote:

Nicole- When will you talk to a doctor--- your MO--- about what all this means? My thoughts are with you.

Found mets on CT for unrelated issue. I only had 2 treatments with IV chemo for the Stage II, then found Stage 4 and switched to hormone therapy/targeted therapy. I consider myself de novo. Xgeva use for bone mets. Liver bx Apr 2021 shows ER- now. Dx 6/2017, ILC/IDC, Left, 3cm, Stage IIB, Grade 3, 0/1 nodes, ER+/PR+, HER2- Surgery 7/11/2017 Lymph node removal: Sentinel; Mastectomy: Left Chemotherapy 7/31/2017 AC Dx 9/2017, ILC/IDC, Stage IV, metastasized to bone/liver, 0/1 nodes, ER+/PR+, HER2- Targeted Therapy 11/1/2017 Ibrance (palbociclib) Hormonal Therapy 11/1/2017 Femara (letrozole), Zoladex (goserelin) Dx 4/2021, ILC/IDC, Stage IV, metastasized to bone/liver, ER-/PR+, HER2- (FISH) Targeted Therapy 9/3/2021 Lynparza Hormonal Therapy 9/4/2021 Zoladex (goserelin)
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Nov 30, 2021 02:22PM ShetlandPony wrote:

Nicole, what a scary development. But wait for the MRI to get better info. If it is a brain met, there are good treatments. Think of Illimae. I'm sorry this is happening!

2011 Stage I ITCs sn, premenopausal, Oncotype 16. 2014 Stage IV mets breast,liver. TaxolNEAD. Ibrance+letrozole 2yrs. Fas+afinitor nope. XelodaNEAD 2yrs. Eribulin,Doxil nope. SUMMIT FaslodexHerceptinNeratinib for Her2mut NEAD 1 1/2yrs. GI/perit mets Dx 2011, ILC, 1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Dx 2014, ILC, 2cm, Stage IV, metastasized to liver/other, Grade 2, ER+/PR+, HER2- Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole-breast: Breast Surgery Lumpectomy
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Nov 30, 2021 02:22PM NicoleRod wrote:

Thanks all. ...Candy ..I dint know ...I didn't get MRI yet I'm still here in ER waiting......

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Nov 30, 2021 04:21PM Kattysmith wrote:

{{{ Oh sweetie, I'm so sorry and will be thinking of you.}}}

First diagnosed borderline Stage 2 IDC, left breast in 2003. No problems until a surprise (!) Stage IV recurrence in 2015! In addition to treatments listed below, I started monthly injections of Xgeva for bone support in July 2016. Dx 10/23/2015, Left, Stage IV, metastasized to other, Grade 3, 0/3 nodes, ER+, HER2- Chemotherapy 11/3/2015 AC Hormonal Therapy 2/4/2016 Femara (letrozole) Targeted Therapy 2/4/2016 Ibrance (palbociclib) Immunotherapy 12/22/2018 Hormonal Therapy Faslodex (fulvestrant)
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Nov 30, 2021 04:21PM BevJen wrote:

Nicole,

Please report in when you can. I'm so sorry. Prayers coming your way.

Microwave Ablations,Liver 3x ;Radiation Therapy to Femur (Both) April 2021; total hip replacement (R) and placement of rod (L) to stabilize femur both sides; immunotherapy (single agent - keytruda) Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/5/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Keytruda (pembrolizumab) Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole) Radiation Therapy
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Nov 30, 2021 05:01PM NicoleRod wrote:

I am probably going to be checking nyself out if hospital before MRI....its a nightmare in here I'm still waiting I would rather just get it out in town . The Neurosurgeon fellow came down and basically ci firmedbits a met its not a white area its a gray black lesion etc. The MRI is just ci firm and get more details. So my question is....obviously my treatment fauled..but no treatment oenetratrs blood brain barrier so what does that mean for brain metzers as far as systemic therapy??

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Nov 30, 2021 05:10PM BevJen wrote:

Nicole,

You should stay there and have this confirmed/denied by other than a fellow. He/she probably doesn't know your whole history or what else this could be. I also don't think that's still true, that nothing can cross the blood/brain barrier. And what of gamma knife?

You need to know what you're dealing with. Take a deep breath and get the MRI done and explained to you. Please.

Microwave Ablations,Liver 3x ;Radiation Therapy to Femur (Both) April 2021; total hip replacement (R) and placement of rod (L) to stabilize femur both sides; immunotherapy (single agent - keytruda) Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/5/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Keytruda (pembrolizumab) Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole) Radiation Therapy
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Nov 30, 2021 05:13PM Husband11 wrote:

It's not correct that systemic treatment drugs don't cross the blood / brain barrier. I've forgotten which one's do, but some do.

I believe they often treat brain mets with radiation, and it's quite effective.

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Nov 30, 2021 05:38PM Moderators wrote:

Nicole, we're here for you! Medicating Here is a link to information regarding radiation treatment methods for brain metastases: Brain Metastasis: Local Treatments. This article has some good context https://www.feinberg.northwestern.edu/_rwd/head.php. There are a lack of effective systemic therapies for brain mets because most don't cross the blood/brain barrier, as you said.

They're working on targeted therapies in clinical trials to improve treatment.

And here is the page for the Brain Mets Sisters.

To send a Private Message to the Mods: community.breastcancer.org/mem...
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Nov 30, 2021 06:04PM Sadiesservant wrote:

Nicole, I'm so sorry this is happening but as others have said, please wait for the MRI to get as much information as possible. It can be treated. Sending hugs.

Dx 4/2001, IDC, Right, 1cm, Stage IIA, Grade 3, 1/10 nodes, ER+ Surgery 5/10/2001 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary Chemotherapy 6/7/2001 CEF Radiation Therapy 12/17/2001 Whole-breast: Breast Hormonal Therapy 12/20/2001 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 1/2/2007 Femara (letrozole) Hormonal Therapy 10/22/2007 Arimidex (anastrozole) Dx 1/3/2017, IDC, Right, Stage IV, metastasized to bone/lungs, ER+/PR+, HER2- Chemotherapy 1/27/2017 Taxol (paclitaxel) Hormonal Therapy 3/28/2017 Arimidex (anastrozole) Targeted Therapy 4/20/2017 Ibrance (palbociclib) Dx 10/12/2017, IDC, Right, Stage IV, metastasized to other Chemotherapy 10/20/2017 Xeloda (capecitabine) Radiation Therapy 11/15/2017 External: Bone Hormonal Therapy 1/18/2018 Faslodex (fulvestrant) Radiation Therapy 8/2/2018 External: Bone Radiation Therapy 11/5/2018 External: Bone Targeted Therapy 10/9/2019 Verzenio Radiation Therapy 11/3/2020 External: Bone Dx 1/22/2021, IDC, Right, 1cm, Stage IV, metastasized to liver, Grade 2, ER+/PR+, HER2- Chemotherapy 2/4/2021 Xeloda (capecitabine) Chemotherapy 10/8/2021 Navelbine (vinorelbine) Chemotherapy 1/7/2022 Halaven (eribulin)
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Nov 30, 2021 06:49PM B-A-P wrote:

Nicole ,

So sorry you’re having to deal with this new development. There are some systematic therapies that cross the BBB and gamma knife is supposed to be really good . With one met, I’d imagine that’s the direction this might take. Hopefully you’ll get answers soon. Thinking of you.



Spoke with the Thrombsis dr and he is saying no to thinners for my portal vein clot. He said the last ct didn’t show it so he’s not confident it’s still there. Though my other drs said CT is not reliable for seeing clots in the portal vein. We had thought this was causing the ascites but according to him it’s the liver damage that is. So hoping that the ibrance kicks in and can dry it up. I know I have cirrhosis too so I’m not sure if I should expect to live with ascites forever. Regardless, bc I had a near fatal bleed in the hospital, I’m at high risk for another so the thinners are out of the question. I’m fine with his recommendations. It’s one thing off my plate

Dx 8/17/2018, IDC, Left, Stage IV, metastasized to liver, ER+/PR+, HER2- (FISH) Chemotherapy 9/17/2018 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Surgery 2/26/2019 Mastectomy: Left, Right Radiation Therapy 4/28/2019 Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy 10/7/2021 Ibrance (palbociclib) Dx IDC, Stage IV, metastasized to liver, ER+/PR-, HER2- (FISH) Hormonal Therapy Femara (letrozole) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Prophylactic ovary removal Chemotherapy Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Faslodex (fulvestrant)
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Nov 30, 2021 07:27PM Husband11 wrote:

BAP, if the ibrance doesn't work as well as expected, try abemaciclib. It may work where ibrance doesn't. My wife made the switch owing to rising tumor markers, and it brought them back down.

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Nov 30, 2021 07:35PM B-A-P wrote:

Husband,

Will definitely bring it up to my MO. I don’t get a Pet scan until mid January so we will see then depending if my body can handle the ibrance with my counts. I have a mid way blood draw this Friday. I might broach the subject with her at my next visit to see what her thoughts are on it. So I know what to expect if ibrance fails

Dx 8/17/2018, IDC, Left, Stage IV, metastasized to liver, ER+/PR+, HER2- (FISH) Chemotherapy 9/17/2018 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Surgery 2/26/2019 Mastectomy: Left, Right Radiation Therapy 4/28/2019 Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy 10/7/2021 Ibrance (palbociclib) Dx IDC, Stage IV, metastasized to liver, ER+/PR-, HER2- (FISH) Hormonal Therapy Femara (letrozole) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Prophylactic ovary removal Chemotherapy Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Faslodex (fulvestrant)
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Nov 30, 2021 07:44PM NicoleRod wrote:

I just had the MRI we don't see any mets in the report are we right??? HISTORY: Frontal mass

COMPARISON: CT head from earlier the same day. Brain MRI 07/26/2021.

TECHNIQUE: MRI of the brain was performed with and without contrast

enhancement. Enhanced images were obtained following intravenous

administration4.6cc Gadavist.

FINDINGS:

There is no evidence of acute infarct, mass, hemorrhage, or

hydrocephalus. There is an approximately 2 cm area of abnormal T2

prolongation the right frontal white matter. This is unchanged compared

with prior MRI and is nonspecific, likely an area of leukomalacia from

prior insult. There is no associated mass effect, hemorrhage, or

abnormal enhancement.

There is a stable moderately extensive area of enhancement in the pons,

likely a developmental venous anomaly.

There is an unchanged 3 mm hypoenhancing area centrally within the

pituitary gland, is likely either a pars intermedia cyst or

microadenoma.

The paranasal sinuses and mastoid air cells are clear.

IMPRESSION :

1. No acute intracranial abnormality identified.

2. There is moderately extensive area of abnormal T2 prolongation the

right frontal white matter. This is long-standing and is nonspecific,

most likely an area of leukomalacia from prior insult.

3. There is moderately extensive area of venous enhancement in the pons,

likely developmental venous anomaly.

4. Unchanged 3 mm hypoenhancing area centrally within the pituitary

gland, likely either a pars intermedia cyst or a microadenoma.

David Mehfoud, MD

11/30/2021 7:27 PM

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Nov 30, 2021 07:46PM - edited Nov 30, 2021 07:48PM by terri-c

This is good, whatever they are looking at has been seen before and is unchanged.

(gentle hugs) keeping you in my prayers Nicole!

Dx 7/7/2011, IDC, <1cm, Stage I, Grade 1, 0/9 nodes, ER+/PR+, HER2- Dx 4/7/2014, IDC, Right, <1cm, Stage IV, metastasized to bone/liver/lungs/other, Grade 2, 0/9 nodes, mets, ER+/PR+, HER2-
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Nov 30, 2021 08:06PM BevJen wrote:

What Terri-C said -- so glad that you had this test done.

Microwave Ablations,Liver 3x ;Radiation Therapy to Femur (Both) April 2021; total hip replacement (R) and placement of rod (L) to stabilize femur both sides; immunotherapy (single agent - keytruda) Dx 11/2003, ILC, Left, Stage IIIC, 13/18 nodes, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+, HER2- Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/5/2019 Targeted Therapy 7/31/2019 Ibrance (palbociclib) Immunotherapy Keytruda (pembrolizumab) Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Femara (letrozole) Radiation Therapy
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Nov 30, 2021 08:25PM NicoleRod wrote:

praise God they came in and confirmed!!! NO CANCER there.

Dx 12/14 Stage 0, Grade 3, ER+/PR, HER2- (FISH),Dx 04/19, Stage IV mets to bone/liver, Hormonal Therapy 04/19 - 10/19 Ibrance/let/faslodex 10/19 **TNBC AUG 2021 Dec 2019-May 2020 Xeloda Failed May-July 2020 - Doxil Failed Dx 12/19/2014, DCIS, Right, Stage 0, Grade 3, ER+/PR+, HER2- (FISH) Dx 2/5/2019, IDC, Right, Stage IIA, Grade 3, ER+/PR-, HER2- Dx 3/2019, Stage IV, metastasized to bone/liver, Grade 3, ER+/PR-, HER2- Hormonal Therapy 4/28/2019 Surgery Chemotherapy Doxil (doxorubicin) Chemotherapy Xeloda (capecitabine) Radiation Therapy Surgery Mastectomy: Left, Right
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Nov 30, 2021 08:48PM - edited Nov 30, 2021 08:51PM by ShetlandPony

What a relief. Bev was right; that fellow did not know as much as he thought he did. So sorry you had to go through the worry. I'm actually pretty ticked off that he would tell you it looked like a brain met without your even having an MRI and a fully qualified person interpret it. How careless of him to just say that and put you through hell.

2011 Stage I ITCs sn, premenopausal, Oncotype 16. 2014 Stage IV mets breast,liver. TaxolNEAD. Ibrance+letrozole 2yrs. Fas+afinitor nope. XelodaNEAD 2yrs. Eribulin,Doxil nope. SUMMIT FaslodexHerceptinNeratinib for Her2mut NEAD 1 1/2yrs. GI/perit mets Dx 2011, ILC, 1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Dx 2014, ILC, 2cm, Stage IV, metastasized to liver/other, Grade 2, ER+/PR+, HER2- Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole-breast: Breast Surgery Lumpectomy
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Nov 30, 2021 09:15PM B-A-P wrote:

Yay Nicole ! What a fright ! I second what Bev said. He put you through such unnecessary worry

Dx 8/17/2018, IDC, Left, Stage IV, metastasized to liver, ER+/PR+, HER2- (FISH) Chemotherapy 9/17/2018 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Surgery 2/26/2019 Mastectomy: Left, Right Radiation Therapy 4/28/2019 Whole-breast: Breast, Lymph nodes, Chest wall Targeted Therapy 10/7/2021 Ibrance (palbociclib) Dx IDC, Stage IV, metastasized to liver, ER+/PR-, HER2- (FISH) Hormonal Therapy Femara (letrozole) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Prophylactic ovary removal Chemotherapy Abraxane (albumin-bound or nab-paclitaxel) Hormonal Therapy Faslodex (fulvestrant)
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Nov 30, 2021 09:52PM SeeQ wrote:

Nicole- what a scare! So glad it was a false alarm. BTW, Verzenio is one that crosses the BBB. I remember my first MO mentioning it when he first started me on it. Here's a recent article that mentions it.

https://pipelinereview.com/index.php/2021101379411...


Diagnosed de novo Stage IV; large liver mets; small breast tumor Dx 6/2/2020, IDC, 6cm+, Stage IV, metastasized to liver, ER+/PR+, HER2- (IHC) Hormonal Therapy 7/2/2020 Arimidex (anastrozole) Targeted Therapy 7/9/2020 Verzenio
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Dec 1, 2021 01:46AM BSandra wrote:

Uh, Nicole, so much has happened overnight. No words can tell how happy I am that nothing was found. Phiu... Saulius

Since May'21:NED. Mar'21:axilla LN surgery. Sep'19-Mar'21:NED. Feb'19:recurrence, left breast,IBC. May'18-Feb'19:NED. Jun'18:DC/CIK. Aug'17:stage IV de novo at age 33. Dx 8/4/2017, IDC, Left, 6cm+, Stage IV, metastasized to liver, Grade 2, ER-/PR-, HER2+ (IHC) Chemotherapy 8/27/2017 Taxotere (docetaxel) Targeted Therapy 8/28/2017 Herceptin (trastuzumab) Targeted Therapy 8/28/2017 Perjeta (pertuzumab) Chemotherapy 3/12/2019 Taxotere (docetaxel) Surgery 7/22/2019 Mastectomy: Left Radiation Therapy 9/9/2019 Whole-breast: Lymph nodes, Chest wall Surgery 4/15/2021 Lymph node removal: Underarm/Axillary Radiation Therapy 12/13/2021 3DCRT: Lymph nodes
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Dec 1, 2021 04:49AM denny10 wrote:

Gee Nicole, I have just caught up on all the posts ,what a horrible time you had. I am glad this stressful incident has ended .

B.A.P. wishing you a long time on Ibrance and hope your port works safely.

12/2021 Stage IV TN Dx 2007, Left, Stage IIB Dx 12/2013, Right, Stage IV, metastasized to liver/lungs/other, ER+
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Dec 1, 2021 07:03AM Husband11 wrote:

That is fantastic Nicole

Concerned husband Dx 2008, Left, Stage IIIB, Grade 3, 7/14 nodes, ER+/PR+, HER2- Dx 5/2016, Stage IV, metastasized to liver, ER+/PR+, HER2- Chemotherapy Xeloda (capecitabine) Targeted Therapy Ibrance (palbociclib) Chemotherapy Hormonal Therapy Femara (letrozole)
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Dec 1, 2021 07:04AM DaughterOf wrote:

Nicole I am so very happy for you. I celebrate all these victories for all of you ladies.

I need a little help.. This might not be the best sub to post in but since my mum is in the same boat as all of you, I was thinking maybe someone had a word of advice for me.

She's currently stable on ibrance and her doctors are looking to use cyber knife on her two largest lesions since they're increasing just a bit. She lives symptom free and apart from knowing she has MBC she feels absolutely fine. However, she has entered a state of horrible anxiety and depression.. She cries and argues with me everyday, doesn't want to do anything, go anywhere, only speaks of dying and how it's all over.. Even though doctors are giving her great chances. I've tried being understanding, tried taking her to trips, suggested psychiatric help.. She won't hear it. We've come to a point where she cries and argues everyday almost all day.. Whatever I say she finds a way to make it seem like she's dying. I am honestly at a loss. I need to know how to help her without also killing myself because this situation has been incredibly hard.

Grateful in advance, a daughter who loves her mother.

Dx 11/2012, IDC, Left, 5cm, Stage IIIC, 4/6 nodes, ER+/PR+, HER2- Dx 6/2021, IDC, Stage IV, metastasized to liver, ER-/PR+, HER2- Chemotherapy FAC Chemotherapy AC + T (Taxol) Surgery Mastectomy: Left Radiation Therapy Whole-breast: Breast Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Femara (letrozole) Targeted Therapy Ibrance (palbociclib)

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