We are 186,055 members in 80 forums discussing 140,354 topics.

Help with Abbreviations

All TopicsForum: Stage IV and Metastatic Breast Cancer ONLY → Topic: Oral Navelbine / Vinorelbine

Topic: Oral Navelbine / Vinorelbine

Forum: Stage IV and Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Jan 21, 2014 10:31AM

Angelfalls wrote:

I found out today that I'll be starting oral Vinorelbine soon (latest scans show the Afinitor/Aromasin combo has stopped working for me), so I'm starting this thread to see if anyone is currently taking it, how you're doing and any top tips you might have... Thanks for any info!

Dx 3/2003, IDC, 6cm+, Stage IIIA, Grade 3, ER+/PR+, HER2- Surgery 3/31/2003 Lymph node removal: Right; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Chemotherapy 4/29/2003 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil), Taxotere (docetaxel) Radiation Therapy 11/14/2003 Hormonal Therapy 1/4/2004 Dx 9/15/2006, 5cm, Stage IV Radiation Therapy 10/31/2006 Surgery 1/30/2007 Prophylactic ovary removal Hormonal Therapy 2/27/2007 Arimidex (anastrozole) Dx 10/5/2011, Stage IV, mets Chemotherapy 1/4/2012 Xeloda (capecitabine) Chemotherapy 3/19/2012 Taxol (paclitaxel) Hormonal Therapy 10/23/2012 Aromasin (exemestane) Targeted Therapy 5/6/2013 Afinitor (everolimus) Hormonal Therapy 1/6/2014 Femara (letrozole) Chemotherapy 1/30/2014 Navelbine (vinorelbine)
Log in to post a reply

Page 1 of 1 (8 results)

Posts 1 - 8 (8 total)

Log in to post a reply

Jan 21, 2014 10:40AM BaseballFan wrote:

Haven't heard of oral Navelbine.  That's convenient!  Hoping for the best for you.

Bobbi Dx 3/14/2009, 6cm+, Stage IV, 11/14 nodes, mets, ER+/PR-, HER2- Surgery 7/22/2009 Lumpectomy: Left; Lymph node removal: Left, Sentinel Surgery 9/30/2009 Lumpectomy: Right Chemotherapy 8/31/2010 Xeloda (capecitabine) Chemotherapy 2/12/2012 Xeloda (capecitabine) Chemotherapy 12/11/2012 Taxol (paclitaxel) Targeted Therapy 1/25/2013 Afinitor (everolimus) Chemotherapy 9/30/2013 Carboplatin (Paraplatin), Gemzar (gemcitabine)
Log in to post a reply

Jan 21, 2014 12:20PM miacouto wrote:

My mother is taking oral navelbine. What I can say is that she lost weight ( 5 kgs so far) since she started the treatment (she has done 4 cycles so far) and SE are worst compared to xeloda. I'm not sure intravenous navelbine would be better but I could guess that it might be. There was a doctor that my mum consulted before she started oral navelbine, which was completely against this oral form because of the toxicity. She told my mother that her patients usually lost a lot of weight on that drug. Anyway, my mum decided to give it a try and I can't wait for it to be over.

All the best for you.

Dx IDC, Stage IV, Grade 2, 16/19 nodes, mets, ER+/PR+, HER2-
Log in to post a reply

Jan 21, 2014 04:23PM lotusblossom wrote:

I have been on intravenous Navelbine for more than 2 years. Oral Navelbine is not available in Canada. I asked about it and was told that the gastro-intestinal SEs can be much worse than with the IV version.

Dx 6/5/2009, Right, <1cm, Stage IV, metastasized to bone/lungs/other, mets, ER-/PR-, HER2-
Log in to post a reply

Jan 21, 2014 09:53PM cheery wrote:

I was on IV Navelbine and wanted to take oral Navelbine on holiday. I was told the cost is much higher for oral tablets and that I'd have to take a higher dosage (not sure if it's due to the bioavailability of tablet form). I decided to skip the dosage eventually as oral tablets was not covered by my insurance. 

I'd great response with Navelbine, hope it does well for you too:) 

Log in to post a reply

Jan 22, 2014 03:46AM Angelfalls wrote:

Thanks for the replies, ladies! Sounds like I'm going to be a bit of a guinea pig for the oral form, then, but that's the way things are moving here in the UK. I'll let you know how I get on...

Dx 3/2003, IDC, 6cm+, Stage IIIA, Grade 3, ER+/PR+, HER2- Surgery 3/31/2003 Lymph node removal: Right; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap Chemotherapy 4/29/2003 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil), Taxotere (docetaxel) Radiation Therapy 11/14/2003 Hormonal Therapy 1/4/2004 Dx 9/15/2006, 5cm, Stage IV Radiation Therapy 10/31/2006 Surgery 1/30/2007 Prophylactic ovary removal Hormonal Therapy 2/27/2007 Arimidex (anastrozole) Dx 10/5/2011, Stage IV, mets Chemotherapy 1/4/2012 Xeloda (capecitabine) Chemotherapy 3/19/2012 Taxol (paclitaxel) Hormonal Therapy 10/23/2012 Aromasin (exemestane) Targeted Therapy 5/6/2013 Afinitor (everolimus) Hormonal Therapy 1/6/2014 Femara (letrozole) Chemotherapy 1/30/2014 Navelbine (vinorelbine)
Log in to post a reply

Apr 22, 2014 12:00PM mutherflush wrote:

Hi Angelfalls. I'm from UK too and I have just finished cycle 2 of oral Navelbine. I had 11 cycles of Xeloda. The Xeloda se's were too much for me in the end. No skin on hands and feet and I was so sore. Onc said I did well to get to 11th cycle. Because they reduced the dose to the lowest possible it stopped working. Hence Navelbine. I believe that they give 3 cycles at 60mg/m2 and the up it on the 4th cycle to 80mg/m2. I will get scan after 4th cycle to see if its working. I have had no real se's apart from feeling tired and a little nausea for two days after treatment. In fact compared to Xeloda it seems a doddle. Wish you well and please keep in touch. We can compare notes. My local hospital says that they have several patients on Navelbine at the moment.

Dx 4/20/2012, Stage IV, ER+, HER2-
Log in to post a reply

Apr 22, 2014 06:44PM SophieJean wrote:

Please do continue to post your experiences - perhaps this is a new approval in Canada. I'm pretty sure I was offered this very recently as a second choice if IV Navelbine caused a particular kind of problem. Was not paying a lot of attention as IV was the reasonable choice since I'm doing it with Cisplatin. I think it will be popular just because of cost saving - much cheaper - even if the drug is more expensive to cut out infusion centre costs. I think you'll be joined by others soon.

Log in to post a reply

Mar 20, 2017 03:38PM stagefree wrote:

and here's where I belong from today on ;)

I will be receiving the first cycle in IV form in a couple of hours, MO planned. She summed up shortly that I wouldn't hopefully be waiting for worse SEs on Navelbine, after my 5-year experience on Xeloda.

I'll be focusing on Navelbine these few days, share my entire experience and info I gather..

From cycle no:2 onwards will be pill form..

MO said be ready in case there's constipation, so as of tonight I quit my entire shouldn't consume items out of my diet :)

I also will be quitting Endoxan, Arimidex, Zoladex shots as well.. just will see Navelbine's performance alone.

Great! Cos I look like a 6-month pregnant woman, being chemically menaupaused.

Guess I'll fit in my clothes soon :) a few pounds to loose is very fine by me!

Anyway,

I'll be updating soon.

Ebru

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine) Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin)

Page 1 of 1 (8 results)