Topic: Ibrance (Palbociclib)

Forum: Stage IV/Metastatic Breast Cancer ONLY — Please respect that this forum is for members with stage IV/metastatic breast cancer ONLY. There is a separate forum for caregivers and friends: Caring for Someone with Stage IV or Mets.

Posted on: Feb 24, 2015 05:21PM - edited Dec 11, 2017 10:43AM by moderators

Posted on: Feb 24, 2015 05:21PM - edited Dec 11, 2017 10:43AM by moderators

Romansma wrote:

A bottle of Ibrance came in the mail today. I will start taking it tonight with Femara. Hoping that others starting on this drug will join me here to talk about side effects and how to avoid or treat them. So far, I've been warned about low white counts. I run very low as it is, probably because of my extensive bone mets. Anyone currently on Ibrance?

Edited by Mods to add Mod Note: Unfortunately, Romansma passed away in 2016. Our thoughts are with all who loved Hope.

Edited by Mods to add:

For more information on this medication, see the main Breastcancer.org site's section on Ibrance for information on how it works, who it's for, what to expect, and side effects. Also, read the latest research on the Research News on Ibrance pages.

Pfizer Oncology Together is a first-of-its-kind program for patients taking Pfizer Oncology medicines that offers dedicated social workers called 'Care Champions' to help navigate the complexities that accompany treatment, such as identifying resources to help find emotional support, and workplace transition, transportation and financial assistance.

For cancer patients taking a Pfizer Oncology medicine (e.g. Ibrance) or caregivers, please visit www.PfizerOncologyTogether.com.

For live support call: 1-877-744-5675

Hope Dx 10/22/2010, ILC, Right, 6cm+, Stage IIIB, Grade 2, 9/10 nodes, ER+/PR+, HER2-, Chemotherapy 11/1/2010 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Chemotherapy 4/1/2011 Abraxane (albumin-bound or nab-paclitaxel), Cytoxan (cyclophosphamide) Radiation Therapy 6/8/2011 Whole breast: Breast, Lymph nodes, Chest wall Surgery 11/29/2011 Prophylactic ovary removal Dx 8/2013, ILC, Stage IV, mets, ER+/PR-, HER2-, Hormonal Therapy 9/17/2013 Faslodex (fulvestrant) Targeted Therapy 1/25/2014 Afinitor (everolimus) Radiation Therapy 2/11/2014 External: Bone Chemotherapy 12/6/2014 Xeloda (capecitabine) Hormonal Therapy 2/20/2015 Femara (letrozole) Targeted Therapy 2/20/2015 Ibrance (palbociclib)
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Jun 21, 2022 03:05PM rk2020 wrote:

Did someone say snacks? I’ll bring the pizza but I’m warning you. You’ve got to be quick grabbing a slice.



Surgery 5/1/2016 Lumpectomy (Right); Lymph node removal (Right): Sentinel Chemotherapy 6/20/2016 AC + T (Taxol) Radiation Therapy 9/1/2016 Whole breast: Right breast Hormonal Therapy 1/1/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 3/10/2020 Faslodex (fulvestrant) Targeted Therapy 3/28/2020 Ibrance (palbociclib) Radiation Therapy 2/22/2021 Other part Hormonal Therapy 9/1/2021 Arimidex (anastrozole) Targeted Therapy 9/1/2021 Verzenio Chemotherapy AC + T (Taxol) Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy External Radiation Therapy Whole breast: Breast, Lymph nodes Local Metastases Radiation therapy: Bone
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Jun 21, 2022 04:15PM lakelandgirl wrote:

Ha!! Great photo! Yes I’ve been THAT hungry for pizza..

Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib)
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Jun 21, 2022 05:16PM aprilgirl1 wrote:

Thanks to all of you for the pocket duty ! It helps so much to know I have people cheering me on, regardless of outcome - with snacks ! Love that pizza photo Rk2020:)

Scan (pet and CT) results are in and all unremarkable ! Reflux in my esophagus showed up again but otherwise it's all clear and they aren't concerned about the reflux as far as breast cancer is concerned. I'll see my new/temp oncologist on Monday 6/27 for faslodex , blood work and an exam .

Sunshine99- sounds like you had a good appt! Onward to cycle 27 for you, which is great ! Cycle 32 or 33 for me start next week assuming my neutrophils are ok. Onward :)

I'm here for pocket duty for anyone who needs it! Snacks....chips and salsa and corona lights with a slice of lime (gee....I can't believe I have reflux ....!)

recurrence in lymph nodes (superclavicle/mediastinal)"You can do it like it's a great weight on you, or you can do it like it's part of the dance." Ram Dass Dx 11/7/2008, IDC, Left, 1cm, Stage IB, Grade 2, 0/3 nodes, ER+/PR+, HER2- Dx 11/13/2019, IDC, Left, Stage IV, metastasized to other, ER+/PR+, HER2-
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Jun 21, 2022 05:50PM dancemom wrote:

I LOVE that Pizza shot 🤣

Restarted Ibrance 4 weeks ago post surgery and radiation. (Cycle 7 or 8? I had to hold so many times for low neutrophils and treatments, im not sure. I started it April 2021) Saw MO and NP yesterday. ANC below 900 again🤨, so I am on hold one more week. Since I'm already on only 75mg, I am now going on a 25 day cycle. 18 on, 7 off. I hope I can keep my Calendar straight! I decided to not bring up that study. I am lucky to see my team in a big teaching hospital, where I know I have been the center of many interdisciplinary conferences (RO told me 40 were in last one!), so I figure they have access to a lot more nuanced info than I do. Scans at some point, not clear when but insurance won't do PET and I have TE so no MRIs until after exchange. (Nov is the plan)

Good news Aprilgirl and sunshine99

Sorry if I double posted. Also, sorry its hard for me to remember who said things on previous pages.


Dx 3/16/2021, IDC, Right, 3cm, Stage IV, metastasized to other, Grade 2, ER+/PR+, HER2- Hormonal Therapy 3/28/2021 Femara (letrozole) Targeted Therapy 4/26/2021 Ibrance (palbociclib) Surgery 1/3/2022 Lymph node removal (Right): Sentinel; Mastectomy (Right): Skin Sparing Surgery 1/3/2022 Lymph node removal (Right): Sentinel; Mastectomy (Right): Skin Sparing Radiation Therapy 3/14/2022 Whole breast, Radiation boost: Right breast, Chest wall, Lymph nodes, Other part
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Jun 22, 2022 02:42AM ciaci wrote:

I'm also in the "If it ain't broke, don't fix it" camp (that was one of my dad's favorite sayings). Next month will be five years on Ibrance/Letrozole for me, starting Cycle 65 next week. I've been NEAD since my first follow-up scan, 4-1/2 years ago. I will happily stay on Ibrance the rest of my life if it will continue to work for me!!

Dx 4/18/2017, IDC, Left, 1cm, Stage IV, metastasized to bone, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 4/23/2017 Lumpectomy; Lumpectomy (Left); Lymph node removal Hormonal Therapy 7/12/2017 Femara (letrozole) Targeted Therapy 7/31/2017 Ibrance (palbociclib)
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Jun 22, 2022 08:00AM sunshine99 wrote:

Pizza sounds good! What a great picture, rk2020!

my-sunny-side-up.com Cancer has progressed to my bones. I pray that it never enters my soul. Dx 11/2/2007, IDC, 3cm, Stage IIA, 0/3 nodes, ER+/PR+, HER2- Dx 3/26/2020, IDC, Stage IV, metastasized to bone, ER+/PR-, HER2- Hormonal Therapy 4/22/2020 Arimidex (anastrozole) Radiation Therapy 5/5/2020 External Local Metastases 5/5/2020 Radiation therapy: Bone Radiation Therapy 5/12/2020 External Local Metastases 5/12/2020 Radiation therapy: Bone Targeted Therapy 6/10/2020 Ibrance (palbociclib)
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Jun 22, 2022 08:10AM rk2020 wrote:

Aprilgirl - Yahoo! Keep the good news rolling! You too Sunshine and Ciaci! Long live the Ibrance dancers

Surgery 5/1/2016 Lumpectomy (Right); Lymph node removal (Right): Sentinel Chemotherapy 6/20/2016 AC + T (Taxol) Radiation Therapy 9/1/2016 Whole breast: Right breast Hormonal Therapy 1/1/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 3/10/2020 Faslodex (fulvestrant) Targeted Therapy 3/28/2020 Ibrance (palbociclib) Radiation Therapy 2/22/2021 Other part Hormonal Therapy 9/1/2021 Arimidex (anastrozole) Targeted Therapy 9/1/2021 Verzenio Chemotherapy AC + T (Taxol) Hormonal Therapy Faslodex (fulvestrant) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy External Radiation Therapy Whole breast: Breast, Lymph nodes Local Metastases Radiation therapy: Bone
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Jun 22, 2022 08:35AM sf-cakes wrote:

I couldn't seem to log on yesterday, wanted to offer a loud WOO-HOO to Aprilgirl for your "unremarkable" scans! And Ciaci, thank you for sharing that your scans are showing NEAD after almost five years! Wonderful! I really needed to hear some good news this morning, thank you soooooo much.

Love that photo RK, that's really my preferred way of eating pizza.

Dancemom, that's an interesting Ibrance schedule, I, too, hope you can keep track with a good calendar and that it keeps your ANC level up!

Hello to everyone else, wishing a peaceful and pizza-filled day ❤️

This is some bullshit. Dx 6/2020, ILC, Left, 6cm+, Stage IIB, Grade 3, 2/4 nodes, ER+/PR-, HER2- Surgery 7/1/2020 Mastectomy; Mastectomy (Left) Chemotherapy 8/4/2020 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 11/3/2020 Chest wall Dx 1/2021, ILC, Left, 6cm+, Stage IV, metastasized to bone, Grade 3, ER+/PR-, HER2- Radiation Therapy 2/9/2021 External Local Metastases 2/9/2021 Radiation therapy: Bone Hormonal Therapy Femara (letrozole) Targeted Therapy Ibrance (palbociclib)
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Jun 23, 2022 07:45AM li77 wrote:

I had the Ibrance study conversation with my MO yesterday. She is also of the mindset that if it’s working, don’t switch. She did say that they can’t get an accurate OS if people in the study are still alive, which is likely the case, and that the progression free period is the more important thing to look at.

Hope everyone is having a good week. We have good friends coming in today to stay with us for a week and a half, so I’m super excited!

Lauren, De Novo Stage IV diagnosis at 44, January 2022. Mets to spine, ribs, iliac bones. Former attorney, current smart ass, mom to an awesome 10-year-old. F this shit. Hormonal Therapy 2/9/2022 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 2/14/2022 Other part Targeted Therapy 4/25/2022 Ibrance (palbociclib) Hormonal Therapy 4/25/2022 Femara (letrozole) Dx IDC, Left, 4cm, Stage IV, Grade 2, ER+/PR+, HER2-
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Jun 26, 2022 09:27AM tanya_djamila wrote:

li77 I’m happy you have a nice visit to look forward too.

Congratulations on good scans ciaci aprilgirl and sunshine!!!

I spoke with my onc about the bc study results and he said he wouldn’t change anything for me bc this ibrance faslodex combination has been working for 5 years. Or according to the study maybe only faslodex has been working and ibrance just providing side effects???? I guess we’ll get the answer to that question soon enough.

Have a great rest of your weekend.

Tany

Tanya Dx 8/19/2003, LCIS, Right, 6cm+, Stage IV, metastasized to bone/other, 28/28 nodes, ER+, HER2- Dx 4/19/2017, Stage IV, metastasized to bone/other, 0/0 nodes, ER+, HER2- Immunotherapy 6/1/2017

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