Feb 25, 2017 06:53PM Cure-ious wrote:
I don't have the same subtype of cancer as you do, (double positive, that's gotta be rare!) but here are some thoughts:
First, for BRCA, I assume you mean you have the BRCA mutation? If so, you should respond well to PARP inhibitors, like Olaparib- these work great in BRCA-mutant cells, and can be given in combination with other drugs too.
You have ER-positive cancer, but so far you have not had Ibrance, has your MO discussed trying Faslodex+Ibrance, or Letrozole +Ibrance?
Lots of other treatments around, Aromasin/Afinitor, Xeloda, etc
If things get really bad, try the NCI immunotherapy trial, some patients apparently have seen amazing results. Here is the link and a phone number to call them to ask questions (you have to go to Bethesda for treatment):
Where are your mets, and how extensive or rapidly moving? that makes a difference for treatment
Anyway, let's bump this up in the thread, so others with history on this type of cancer can jump in. Hang on and Good luck!