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Topic: Zoladex belly: how long before I come back normal?

Forum: Stage IV and Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Apr 15, 2017 03:39AM

stagefree wrote:

hi all,

I'd been on monthly Zoladex shots till last month and the last 6 months developed a pregnancy-like belly. It doesn't look at all like fat belly. Not yet had my first period after Zoladex, yet. Can anyone with similar experience tell what to expect? Seriously need input, planning my new wardrobe :(

Hugs

Ebru

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)
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Apr 16, 2017 01:59PM stagefree wrote:

oh come on! I can't be alone in this??

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)
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Apr 16, 2017 07:07PM artistatheart wrote:

Hi Ebru,

I haven't dealt with anything like that yet, and not to scare you but that sounds like what many women describe when they develop ascites....had any scans lately to rule that out? Or maybe the other meds are postponing your period so residual bloating? Sorry I can't be of more help......

Dx 7/22/2015, ILC, Left, 4cm, Stage IV, Grade 3, ER+/PR+, HER2- Hormonal Therapy 8/9/2015 Femara (letrozole) Targeted Therapy 8/25/2015 Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant)
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Apr 16, 2017 09:06PM susan_02143 wrote:

My dear StageFree.

I haven't been on that drug, much less left it behind, so no intel to offer. Just sending you my best thoughts.... you must be off to the countryside soon. You are so very happy there. How is your little guy doing?

*susan*

anotherplan.blogspot.com... and its back. May 3, 2010 mets found. Five years NED on Faslodex * 4/2015 progression to bone * 6/11/2015 Femara/Ibrance * 12/27/2015 Xeloda * 2/24/2016 Xgeva * another progression, another drug Taxol 2/14/2017 Dx 6/8/2005, IDC, 3cm, Stage IIB, Grade 1, 0/3 nodes, ER+/PR+, HER2-
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Apr 17, 2017 12:27AM stagefree wrote:

thank you both :)

I got a lovely pm explaining the matter, seems like it's because of Zoladex, though I will be having a MRI in case, this week.

Susan, my chemo schedule isn't yet clear.. we need to see if Navy is in fact working. MO will decide in two weeks. I may move onto Gemzar. If so, then will stay in Istanbul mostly. :/

He's grown, twelve now. I am so happy to spend each sec with him, though we're like cats and dogs now that he hit puberty ;)

Oh well, Xeloda life was so good to be teue, a bit of chaos in treatment doesn't shake me.. TM's back to 3000 :₺))) who looks at them, still feel ok

Love to all

Ebru

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)
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Apr 17, 2017 09:45PM - edited Apr 17, 2017 09:46PM by JFL

Ebru, I haven't specifically had an issue isolated to the belly, but both times when I went off hormone therapy, I quickly gained 6-10 pounds due to an estrogen "surge", as my MO called it. It happened on tamoxifen when I was premenopausal and even on aromsain/faslodex after I had my ovaries removed. I have an easier time maintaining my weight when estrogen is shut down. In both cases, I was able to clamor back to my normal weight within 6 months.

Dx at 30. Dx with mets at 38 while pregnant. Extensive liver and bone involvement. Currently on Afinitor, Aromasin and XGeva. Dx 9/2006, IDC, Stage IIB, Grade 3, ER+/PR+, HER2- Surgery 9/22/2006 Mastectomy: Left, Right Chemotherapy 11/6/2006 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 3/15/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 12/2014, IDC, Stage IV, metastasized to bone/liver/other, Grade 3, ER+/PR-, HER2- Chemotherapy 12/17/2014 Taxotere (docetaxel) Surgery 12/26/2014 Prophylactic ovary removal Hormonal Therapy 12/26/2014 Aromasin (exemestane), Faslodex (fulvestrant) Targeted Therapy 6/18/2015 Ibrance (palbociclib) Chemotherapy 3/10/2016 Xeloda (capecitabine) Hormonal Therapy 5/14/2017 Aromasin (exemestane) Targeted Therapy 5/14/2017 Afinitor (everolimus)
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Apr 18, 2017 02:04AM stagefree wrote:

hi JFL,

Thanx for the response. I showed Dh my belly last night and he agreed there's a slight difference to what it was a month ago, I was 6 month pregnant looking. I don't care how I look, it's just that being so bloated Has much impact on my physical activity.

Weird, I have a wardrobe of clothes ranging from 2-16 now :) quit getting rid of stuff as my size changes each day ha ha ;)

Hugs

Ebr

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)
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Apr 18, 2017 09:23PM Bestbird wrote:

Dearest Ebru, I am so sorry you have a swollen belly and hope the cause will be found soon. Please ensure that your abdomen and pelvic area are checked for fluid as well as a blockage. I've never heard of Zoladex causing abdominal swelling nor is it listed as a side effect of the medication.

I hope that the cause is found and that you get back to your normal size soon!


Dx 10/6/2011, IDC, Left, Stage IV, ER+/PR+, HER2-
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Apr 19, 2017 04:44AM stagefree wrote:

dear Anne,

Thnx as always you are soo thoughtful and considerare. I am blessed to have you as my friend. This weekend I have a MRI, hope to give good news soon👍🏼

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)
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Apr 19, 2017 09:35PM Bestbird wrote:

Dearest Ebru, You are in my prayers nightly, and have been for years. I wish for you that your medical team will find an answer to this puzzle, that it will be easy to remedy, and that you will soon be back to your usual self!

Wouldn't it be wonderful if it were merely gas? : )

Sending you warm hugs and good wishes!

Dx 10/6/2011, IDC, Left, Stage IV, ER+/PR+, HER2-
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Apr 20, 2017 01:39PM MeToo14 wrote:

I have read that a lot of people have bloating with Zoladex. I too have issues with it. Bloating is a symptom of menopause and Zoladex shuts down your ovaries and essentially puts you into menopause. I will go through periods of bad bloating and some days I will wake up with a flat stomach and by the afternoon, I have a big belly and am very bloated.

35 when diagnosed. I had isolated tumor cells in my nodes and was told I am considered node negative, I do not. Dx 7/2014, IDC, 5cm, Stage IIIA, Grade 2, 2/3 nodes, ER+, HER2- Chemotherapy 7/13/2014 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 11/24/2014 Lumpectomy: Right; Lymph node removal: Right, Sentinel Surgery 12/25/2014 Lumpectomy: Right Chemotherapy 1/1/2015 Carboplatin (Paraplatin) Radiation Therapy 4/26/2015 Hormonal Therapy 7/19/2015 Aromasin (exemestane), Zoladex (goserelin)
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Apr 22, 2017 04:54AM stagefree wrote:

Hi all,

Today I have detailed MRI, hope to receive the answers soon. Meanwhile I shunk to half, thank God! I returned all new large tişörts I ordered online yesterday ;)

Good to still fit to old clothes!

Hugs

Ebru

Dx 4/9/2012, IDC, Stage IV, Grade 1, mets, ER+/PR-, HER2- Chemotherapy 4/11/2012 Xeloda (capecitabine) Hormonal Therapy 8/24/2012 Hormonal Therapy 6/8/2016 Arimidex (anastrozole), Zoladex (goserelin) Chemotherapy 6/8/2016 Cytoxan (cyclophosphamide), Xeloda (capecitabine)

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