A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.
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May 25, 2018 12:48AM
That is certainly the conundrum with timing and clinical trials - one usually needs to be at the stage of treatment failure to qualify for a trial but waiting around for the trial to process its paperwork/get a patient set up and rolling in the trail typically results in significant delay and time without treatment. Something to keep in mind and to ask the doctor about so that if your mom does go the trial route, she knows what to expect regarding treatment delay. I do research a lot of trials and have applied for a hand full but this issue is what has stopped me from biting the bullet so far - worry about treatment delay, given the aggressive, fast-growing nature of my BC. Has your mom already done other standard therapies aside from AC? One factor in weighing clinical trials is the availability of good alternatives. It may not be necessary to go to a trial at this point if there are a lot of good therapies out there that are already proven to be effective (like Abraxane). Good luck determining the next step for your mom.
Chart your own course. Dx at 30. Dx with mets at 38 while pregnant. Extensive liver and bone involvement. Currently on Doxil and XGeva. ER+/PR+, HER2 equivocal (IHC)/negative (FISH) as of 8/2017 liver biopsy.
9/2006, IDC, Stage IIB, Grade 3, ER+/PR+, HER2- (FISH)
9/22/2006 Mastectomy: Left, Right
11/6/2006 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel)
3/15/2007 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
12/2014, IDC, Stage IV, metastasized to bone/liver/other, Grade 3, ER+/PR-, HER2-
12/26/2014 Prophylactic ovary removal
12/26/2014 Aromasin (exemestane), Faslodex (fulvestrant)
6/18/2015 Ibrance (palbociclib)
3/10/2016 Xeloda (capecitabine)
5/14/2017 Aromasin (exemestane)
5/14/2017 Afinitor (everolimus)
8/18/2017 Abraxane (albumin-bound or nab-paclitaxel)
3/23/2018 Doxil (doxorubicin)