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Topic: The HER2CLIMB-02 trial is enrolling!

Forum: Stage IV/Metastatic Breast Cancer ONLY —

A place for those managing the ups & downs of a Stage IV/metastatic breast cancer diagnosis. Please respect that this forum is for Stage IV members only. There is a separate forum For Family and Caregivers of People with a STAGE IV Diagnosis.

Posted on: Jun 22, 2020 02:49PM

Moderators wrote:

The HER2CLIMB-02 trial is enrolling people diagnosed with advanced-stage HER2-positive breast cancer:

The HER2CLIMB-02 trial ( is looking to see if Tukysa (chemical name: tucatinib) given in combination with Kadcyla (chemical name: T-DM1 or ado-trastuzumab emtansine) will offer more benefits than Kadcyla alone in people diagnosed with:

  • metastatic HER2-positive breast cancer
  • locally-advanced HER2-positive disease that can't be completely removed with surgery
  • • a taxane chemotherapy, such as Taxotere (chemical name: docetaxel) or Taxol (chemical name: paclitaxel)
  • • Herceptin (chemical name: trastuzumab)

The HER2CLIMB-02 trial is being conducted at multiple sites around the world and the United States. For a complete list of sites, visit

For more information on detailed eligibility requirements or to enroll

Visit the You also may email or call 1-866-333-7436.

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