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Topic: Now Enrolling: DESTINY-Breast02 Trial for HER2+ adv/mets

Forum: Stage IV/Metastatic Breast Cancer ONLY —

Please respect that this forum is for members with stage IV/metastatic breast cancer only. There is a separate forum for caregivers and friends: Caring for Someone with Stage 4 or Mets.

Metastatic breast cancer (MBC; also called stage IV) is breast cancer that has spread to other parts of the body, most commonly the bones, liver, brain, or lungs. Metastatic breast cancer can be treated but not cured. Metastatic disease is NOT hopeless. There are a wide variety of treatment options for metastatic breast cancer, and new medicines are being tested every day. More and more people are living life to the fullest while being treated for metastatic breast cancer.

Note: Please contact your doctor for any specific concerns about symptoms you are experiencing or your course of treatment.

Learn more about living with MBC.

Intro medically reviewed by: Brian Wojciechowski, M.D.
Last review date: November 22, 2020

Posted on: Aug 28, 2020 02:18AM

Moderators wrote:

The DESTINY-Breast02 trial is a phase III trial for people diagnosed with metastatic HER2-positive breast cancer or other stages of HER2-positive disease that can't be removed with surgery and have been previously treated with Kadcyla (chemical name: T-DM1 or ado-trastuzumab emtansine).

The trial is looking to see if the medicine fam-trastuzumab-deruxtecan-nxki offers more benefits than either Herceptin (chemical name: trastuzumab) and Xeloda (chemical name: capecitabine) or Tykerb (chemical name: lapatinib) and Xeloda.

Learn more.

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