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Dec 3, 2012 09:15PM
Be careful with all the extra fluids. I also requested and got 500 ml of fluid with every infusion, which was weekly. I kept feeling like I was being inflated so I mentioned it to the MO at today's appt and it seems I am retaining lots of those fluids. After 12 weeks, I am literally turning into the Michilin woman! Even my bras are tight now, because my newly reconstructed foobs, which started out smallish (which I liked) are now big.
It is so hard to figure out what is the right balance. I have heard that lots of fluids help flush out the chemicals, but I guess too much isn't good either. It seems there is a difference between the way my body processes infusion fluids and fluids that I drink. This week, I will try the herceptin without any additional fluids and will try and drink more (even though I think I am drinking more now then I ever have before!!)
As for the clinical trial, I can opt out any time I want. Also, another benefit of metformin is that it causes weight loss--although that may be from the GI issues. My main objection is the 2 pills a day requirement. Before BC, I never took any medication and was relatively healthy, but somewhat overweight. The prospect of having to take pills every morning and every night is daunting, especially if it is only a placebo.
I'm already participating in a clinical trial regarding diagnosis of breast cancer. From what I understand, they are tracking certain markers in blood. That trial only asks for blood every six months for 5 years.
6/14/2012, IDC, 1cm, Stage I, Grade 3, 0/1 nodes, ER+/PR+, HER2+
7/25/2012 Mastectomy: Left, Right; Reconstruction (left): Latissimus dorsi flap, Tissue expander placement; Reconstruction (right): Latissimus dorsi flap, Tissue expander placement
9/12/2012 Herceptin (trastuzumab)
9/12/2012 Carboplatin (Paraplatin), Taxotere (docetaxel)
2/4/2013 Reconstruction (left); Reconstruction (right)