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All TopicsForum: HER2+ (Positive) Breast Cancer → Topic: TRIPLE POSITIVE GROUP

Topic: TRIPLE POSITIVE GROUP

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jan 31, 2011 07:30AM - edited Dec 10, 2012 08:55AM by TonLee

TonLee wrote:

This is primarily for people who find themselves with THREE +'s by their diagnosis. 

If you are new to breast cancer, please click on the link below and read.  It is "What I Wish I Knew At the Beginning of Treatment."

http://community.breastcancer.org/forum/6/topic/797454



IDC, 2cm, Stage IIIa, Grade 2, 4/4 nodes, ER+/PR+/HER2+, Skin Sparing uni-MX with TE, TCH, Rads Dx 9/14/2010, IDC, 2cm, Stage IIIA, Grade 2, 4/4 nodes, ER+/PR+, HER2+
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May 27, 2017 07:45PM SpecialK wrote:

Hap - brachytherapy is a type of internal radiation that is more targeted to the lumpectomy be and a shorter duration type, usually a week.

http://www.breastcancer.org/treatment/radiation/types/internal


BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 28, 2017 09:13AM PoseyGirl wrote:

Hi Jeaniraye, I am Canadian, as you are. There are drugs offered in the US that aren't covered here. The major one is Perjeta; it is covered for stage 4. I did meet a woman ftom out west about your age that fought for use of Perjeta in her treatment; her oncologist okayed the prescription, but she had to pay for it off label and have it infused at a private clinic. If you're done radiation and chemo, you would likely have a harder time getting your MO to agree to Perjeta (did you get a complete response from chemo?). As for oophorectomy, doctors don't like to suggest it for women under 45, especially under 40. The ovaries do a lot for us that I didn't even know. I had the surgery, but I am 48 and was likely 2 or 3 years from menopause occurring naturally. I'm not thrilled with the possible risks, but it felt right for me.

Radiation Therapy 1/11/2016 Whole-breast: Breast, Lymph nodes, Chest wall Dx 6/23/2016, IDC, Right, 6cm+, Stage IIIA, Grade 3, ER+/PR+, HER2+ (IHC) Chemotherapy 7/11/2016 AC + T (Taxol) Targeted Therapy 9/15/2016 Herceptin (trastuzumab) Surgery 11/29/2016 Lymph node removal: Right; Mastectomy: Right Hormonal Therapy 12/21/2016 Femara (letrozole)
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May 28, 2017 10:09AM SpecialK wrote:

hap - not enough is known about the effectiveness of Herceptin as a stand alone treatment yet for the vast majority of oncologists to prescribe it without accompanying chemotherapeutic agents for early stage patients. We have one participant in this thread that is receiving Herceptin without chemo, but she is participating in a clinical trial. I am only aware of one other member on BCO who had Herceptin alone, and she progressed from early stage to stage IV and has now received chemo. Other stage IV ladies receive Herceptin alone for maintenance longer than the 12 months, and after chemo. Generally, oncologists will only forego the chemo if you have a co-morbidity that endangers you.

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 28, 2017 01:28PM SpecialK wrote:

hap - in addition to my own breast cancer and many skin cancers, as well as a rare but benign tumor that was removed from my leg, my brother had stage IV bile duct cancer, and my dad stage IV lung cancer. I have had a number of close friends with breast cancer - both before and after mine - and two of them were single women, one 35 and one 69. I went with both to their surgeries and treatment since they did not have family locally. I have also had several friends with other types of cancer that I have accompanied to consults and treatment also. Co-morbidity in the sense of not tolerating chemo is generally considered to be heart disease, liver disease, kidney disease, or something that makes tolerating the chemo drugs dangerous to the patient. Your oncologist will be able to explain whether your previous cancer is something that would preclude being able to receive Taxol. A single agent chemo regimen is usually considerably easier to tolerate than a multi-drug regimen, and your MO can reduce the dose, or you can certainly stop, if you find you are not able to handle any side effects. From what I have witnessed, chemo side effects are generally not permanent and the time it takes to feel pretty normal is about as long as the time period you were receiving the drug. I understand the concern about being debilitated, we all share it, and it is a legitimate fear Interestingly, I have found in both my personal experience, and here on BCO, age is less of a factor in who does well with chemo - you would think youth and strength would prevail but it does not guarantee an easier ride. I had a lady that sat next to me at chemo who had fallen and broken her hip leaving the surgery center after her lumpectomy. She recovered, then started chemo and did beautifully, she was in her 70's. You just never know! Have you had the opportunity to have a frank discussion with your oncologist about your concerns?

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 28, 2017 08:28PM moodyblues wrote:

Specialk you are awesome, I watch your posts to glean your wisdom.  I am grateful for your knowledge and for all of the ladies who are walking us through.  I will finally start Wednesday. 

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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May 28, 2017 09:26PM kae_md99 wrote:

will removal of ovaries for premenopausal women reduce the risk of recurrence for er positive who will be on lupron and AI? or is lupron and AI enough?

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 28, 2017 11:41PM SpecialK wrote:

hap - if you feel confident in your oncologist's recommendation after a careful review of your health concerns, I think it is worth a try. I'm sure your daughter is worried - I know mine was!

moody - sweet compliment! The silver lining of my personal experience is helping others - glad that anything I have said has been useful!

Kae - the SOFT and TEXT trials both point to an advantage for younger premenopausal patients to use ovarian suppression for recurrence prevention. Having an ooph would mean you could avoid Lupron, but the younger you are the greater the potential for heart and bone issues that stem from the lost eatrogen


BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 28, 2017 11:57PM kae_md99 wrote:

specialK,i am 44 years old and i will be taking AI and i have already started Lupron. thanks

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 29, 2017 12:17AM PatinMN wrote:

HapB, I had taxol and herceptin, and was 60 when diagnosed. It wasn't bad - other than some manageable issues with constipation and diarrhea, I felt fine throughout. I did take l-glutamine and B6 to ward off neuropathy, when I started to feel some twinges after about the third treatment. I had hoped to persuade my oncologist to give me herceptin alone, but he wouldn't do it. After reading more about the aggressiveness of HER2 tumors, I was glad I got taxol too. My tumor was 5mm.

Dx 7/13/2012, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR-, HER2+ Surgery 7/31/2012 Lumpectomy: Left Targeted Therapy 9/19/2012 Herceptin (trastuzumab) Chemotherapy 9/19/2012 Taxol (paclitaxel) Radiation Therapy 1/7/2013 Breast Hormonal Therapy 3/31/2013
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May 29, 2017 12:47AM Taco1946 wrote:

Hap - our diagnosis look about the same although I haven't had cancer previously. Had a intercerebral bleed 10 years ago and my recovery from that has left me grateful. I did 8 rounds of taxol but the neuropathy got bad and I quit. (I too had the feeling that I should finish it for my family but my MO said I had had enough to make if work.) Side effects left me within a few weeks. Herceptin has been fine. I'm having some joint pain, especially first thing in the morning, from the daily pills (tried to go back to get the spelling of it and lost the whole message) but it is manageable and gets better as the day goes on. It hasn't been uncomfortable enough that I don't continue with life as it was before. My very best friend lived with stage 4 for 5 years and entered hospice care about the time I was diagnosed. She never let herself be a victim and I learned much from her, including I think, that I will know when I have had enough. I'm guessing you will too. Not a lot of us seniors on these threads so know especially that I am thinking about you and do understand your reluctance to have lots of invasive treatments.


Dx 11/22/2016, IDC, Left, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2+ Radiation Therapy 12/29/2016 Balloon-catheter: Breast Chemotherapy 2/3/2017 Taxol (paclitaxel) Targeted Therapy 2/3/2017 Herceptin (trastuzumab) Hormonal Therapy 12/4/2017 Femara (letrozole) Targeted Therapy Surgery Lumpectomy: Left; Lymph node removal: Sentinel, Underarm/Axillary
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May 29, 2017 09:26AM PatinMN wrote:

HapB, yes, I worked 4 days a week during treatment, and walked/did mild exercise at the gym 3 to 4 days a week. Always driving myself as I live alone. I used cold caps to save my hair, and was therefore able to keep my privacy at work (except for those I worked with directly, who of course needed to know why I was only there 4 days a week). My heart function remained in the normal level. A lot of people are affected so much by the Benadryl you get with taxol that they don't feel they can drive home after treatment; by the time I finished cold capping (four hours after finishing taxol) I could have driven, but my employers hired a limo service for me on chemo days!

Dx 7/13/2012, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR-, HER2+ Surgery 7/31/2012 Lumpectomy: Left Targeted Therapy 9/19/2012 Herceptin (trastuzumab) Chemotherapy 9/19/2012 Taxol (paclitaxel) Radiation Therapy 1/7/2013 Breast Hormonal Therapy 3/31/2013
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May 30, 2017 07:57AM PatinMN wrote:

HapB, I used Penguin cold caps, and they work really well with weekly taxol. I wouldn't say I had no side effects from taxol - but they weren't bad by comparison with other chemo regimens.

Dx 7/13/2012, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR-, HER2+ Surgery 7/31/2012 Lumpectomy: Left Targeted Therapy 9/19/2012 Herceptin (trastuzumab) Chemotherapy 9/19/2012 Taxol (paclitaxel) Radiation Therapy 1/7/2013 Breast Hormonal Therapy 3/31/2013
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May 30, 2017 06:23PM kae_md99 wrote:

when did your hair start growing after chemo? did you use any shampoo/ supplements to help ? thanks

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 30, 2017 07:31PM - edited May 30, 2017 07:32PM by SpecialK

It took me 4 months to have enough hair to go without a wig, and I took Biotin, 5,000mcg a day, I also used Bosley shampoo from my hairdresser.

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 30, 2017 07:33PM kae_md99 wrote:

Thanks SpecialK. anybody here with experience with Rogaine?

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 30, 2017 07:33PM ElaineTherese wrote:

Four months is about right. I finished chemo in December and was going wig-less by March. It was quite a shock for my students as I went from someone with shoulder length-hair to a very short do in a few days.

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/22/2014 AC Targeted Therapy 9/16/2014 Perjeta (pertuzumab) Targeted Therapy 9/16/2014 Herceptin (trastuzumab) Chemotherapy 9/16/2014 Taxol (paclitaxel) Surgery 1/11/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/24/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/8/2015 Breast, Lymph nodes
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May 30, 2017 07:41PM kae_md99 wrote:

Thanks Elaine , my kids are freaked out with my bald head ,they run away if i don't wear my beanie in the house and i cannot wear a wig... so a little help speeding up the growth after last chemo will help.

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 30, 2017 08:34PM Tresjoli2 wrote:

Kae my kids couldn't handle it either. I had to wear scarves all the time.

Diagnosed at age 40 after going for my baseline mammogram. Dx 4/21/2015, IDC, Left, <1cm, Stage IA, 0/2 nodes, ER+/PR+, HER2+ (FISH) Dx 4/21/2015, DCIS, Left, 4cm, Stage 0, Grade 3 Surgery 5/18/2015 Lumpectomy: Left; Lymph node removal: Sentinel Targeted Therapy 6/19/2015 Herceptin (trastuzumab) Chemotherapy 6/19/2015 Taxol (paclitaxel) Chemotherapy 8/7/2015 Abraxane (albumin-bound or nab-paclitaxel) Radiation Therapy 9/23/2015 Whole-breast: Breast Hormonal Therapy 10/11/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 30, 2017 10:27PM SpecialK wrote:

hap - an LVEF of at least 50 is considered normal, and is usually anywhere between 50 and 70. When monitoring heart function during Herceptin doctors look for a 10 point drop, or a 10% drop between quarterly echos or MUGA scans. If you sustain a drop that is deemed unacceptable, Herceptin can be postponed or discontinued.

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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May 31, 2017 06:25AM HelenWNZ wrote:

I finished chemo in October and went hatless in January. It was summer and so hot. My hair was so short but I thought it's the other persons problem not mine. Last week I had my first haircut. More like a trim really to try and sort out my grey poodle mop of hair. My echo results are considered normal at 58 a drop from 64 to 68 in the beginning. I only have 4 herceptin to go so if I keep plodding on she'll be right. I'm so looking forward to finishing the herceptin as I will then find out what side effects can be attributed to letrozole. Actually today is one year since my surgery what a crazy journey I'd much rather not be on. Take care everyone

Helen W Dx 5/5/2016, DCIS/IDC, Left, 3cm, Stage IIIC, Grade 2, 18/22 nodes, ER+/PR+, HER2+ (IHC) Surgery 5/31/2016 Lymph node removal: Underarm/Axillary; Mastectomy: Left Chemotherapy 7/7/2016 Taxotere (docetaxel) Targeted Therapy 7/8/2016 Herceptin (trastuzumab) Chemotherapy 9/6/2016 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Radiation Therapy 11/20/2016 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 1/6/2017 Femara (letrozole)
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May 31, 2017 10:37AM Suburbs wrote:

Hi all. The lesion found on a CT scan was removed last week via an out patient procedure under general anesthesia. I won't get my results until next week. The waiting is torture.

I have a BMX with reconstruction scheduled in a few weeks. I'm not sure if the one surgery and outcome will put the brakes on the plan for the second. This is rather ironic as I had started out convinced I would not have reconstruction. I am on week three of Prozac. Appointments with surgeons and more waiting are upcoming.

TCHP number 6 has put me out of commission for two solid weeks moving from couch to bed in a state of total inertia. That cumulative effect of chemo really sneaks up on you. My eye brows which had been thinning slightly basically fell off after TCHP number 6. I will lose only two nails, one on each hand, soon.

Today, I feel some energy returning, ready to get back on my tread mill and join the land of the living while avoiding looking in any mirrors. Thanks for listening to my tales of woe as it's been cathartic to post them. Onward.


Dx 1/9/2017, DCIS/IDC, Right, 2cm, Stage IIA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ (IHC) Targeted Therapy 1/31/2017 Herceptin (trastuzumab) Chemotherapy 2/1/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 6/20/2017 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Hormonal Therapy 7/21/2017 Arimidex (anastrozole) Targeted Therapy 2/1/2018 Nerlynx
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May 31, 2017 11:08AM shelabela wrote:

I did not lose any nails! I had one that started to lift but that was it. Now that I have completed the 12 weeks of Taxol it is back to normal.

I am on AC right now and it is totally kicking my butt! But I only have one more of these and I am done! Yay!!!!!

After my last Chemo on June 12 I have a few weeks of "rest" then I have a total Mastectomy on July 19th. I am told I will need to have at least 4 nodes removed and then they will test the others at the time of surgery to see if more need to removed. Then I will have rads for 5 weeks. When I started this journey I never thought I would get through Chemo, Seemed like so long.

My MO talked to me yesterday about what would come after all this. Herceptin for a year then Tamoxifin (SP) for 10 years she said. Maybe talked about removing my ovaries, So many things to think about. If they remove my ovaries will I not need to Tamoxifin for 10 years???? If removing them doesn't make a difference why do it? Anyones else dr talk about this? I am only 43, and where as I am done with having kids and could care less about anything like that.

Diagnosed at age 43 Dx 1/10/2017, IDC, Left, 4cm, Stage IIIB, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/5/2017 Taxol (paclitaxel) Targeted Therapy 2/5/2017 Herceptin (trastuzumab) Targeted Therapy 2/5/2017 Perjeta (pertuzumab) Chemotherapy 5/1/2017 AC Surgery 7/19/2017 Lymph node removal: Sentinel, Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Targeted Therapy 8/2/2017 Herceptin (trastuzumab) Radiation Therapy 9/18/2017 Whole-breast: Breast, Lymph nodes Hormonal Therapy 10/11/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 31, 2017 11:16AM bareclaws wrote:

shelabala, good about the nails! I've got six Taxol done (after AC, so ours was just the opposite) and nails seem OK so far. They have changed shape somewhat, but no darkening or lifting. I keep them short, still trimming them every week, and unpolished. I'malso icing during Taxol.

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May 31, 2017 11:18AM ElaineTherese wrote:

Suburbs, sorry to hear you're waiting for test results (again). My eyebrows have never fully recovered from chemo; I just pencil them in a bit. And, my poor eyelashes are still thin and stubby.

Shelabela, Yeah, AC was worse than Taxol. The SOFT study showed that ovarian suppression (or an oopherectomy) + Tamoxifen was more effective than Tamoxifen alone for younger (pre-menopausal) women. You could do ovulation suppression (monthly shot of Zoladex or shot of Lupron every three months), but an oopherectomy accomplishes the same thing. The SOFT study also showed that ovarian suppression + an aromatase inhibitor was better than tamoxifen or an AI alone for younger cancer patients. I'm currently doing Zoladex + Aromasin, but will talk to my new OB/GYN about an oopherectomy on Monday. My old OB/GYN was not a fan of oophs; he said that overall, women who kept their ovaries lived longer than women who didn't. But, I'm not sure that I want to take Zoladex for several more years. Hope this helps!

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/22/2014 AC Targeted Therapy 9/16/2014 Perjeta (pertuzumab) Targeted Therapy 9/16/2014 Herceptin (trastuzumab) Chemotherapy 9/16/2014 Taxol (paclitaxel) Surgery 1/11/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/24/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/8/2015 Breast, Lymph nodes
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May 31, 2017 11:25AM shelabela wrote:

ElaineTherese,

Yes that does give me some more to go off. Is this SOFT study online yet. Can I check out info about it?

Diagnosed at age 43 Dx 1/10/2017, IDC, Left, 4cm, Stage IIIB, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/5/2017 Taxol (paclitaxel) Targeted Therapy 2/5/2017 Herceptin (trastuzumab) Targeted Therapy 2/5/2017 Perjeta (pertuzumab) Chemotherapy 5/1/2017 AC Surgery 7/19/2017 Lymph node removal: Sentinel, Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Targeted Therapy 8/2/2017 Herceptin (trastuzumab) Radiation Therapy 9/18/2017 Whole-breast: Breast, Lymph nodes Hormonal Therapy 10/11/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 31, 2017 11:54AM ElaineTherese wrote:

Shelabela,

You can Google "SOFT study and breast cancer" to find info about it.

Here's a link to the journal article:

http://www.nejm.org/doi/full/10.1056/NEJMoa1412379#t=article

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/22/2014 AC Targeted Therapy 9/16/2014 Perjeta (pertuzumab) Targeted Therapy 9/16/2014 Herceptin (trastuzumab) Chemotherapy 9/16/2014 Taxol (paclitaxel) Surgery 1/11/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/24/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/8/2015 Breast, Lymph nodes
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May 31, 2017 02:18PM kae_md99 wrote:

i started Lupron more than a month ago and now i am feeling the SEs. joint pains,insomia,cold/hot flashes. i did wonder today if its just better to have oophorectomy, will have to ask my OBGYne. i will be on Lupron and AI for 5 years and i will turn 45 in a month....

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 31, 2017 02:41PM - edited May 31, 2017 02:46PM by sportsmom16

Hi All- posted last week about anti-depressants and interaction with Tamoxfin-apparently almost no one else is having these concerns so I am going to broaden my question as to what folks did to fight depression- wonder if everyone else just toughed it out-

I am crying everyday and not sure why- the remaining Hercepton treatments aren't bad and don't think the reconstruction will be as hard as the mastectomy so not sure why I am completely breaking down now. Did anyone else take anti-depressants to get through that - is it a bad idea-- I cant go back to work crying every morning- tried meditation, journaling, exercise, writing gratitude lists- not moving forward - just cried the entire way on my walk- at my wits end

Dx 9/13/2016, IDC, Left, 2cm, Stage IIB, Grade 3, 0/2 nodes, ER+/PR+, HER2+
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May 31, 2017 04:21PM kae_md99 wrote:

hi sportsmom, i am like that sometimes. i will have my last TCHP on friday and chemo was brutal which caused my anxiety. my PCP gave me anti anxiety pills, clonopin and it helped a lot. just wanted to share. i dont know though if it has interaction with Tamoxifen...

kae, 1-10-17, IDC,2.5 cm, right,er,pr,her2 (+),grade 2;DCIS, left, er,per(+),grade 2; 2-17-17- Taxotere, Carboplatin ; 2-17-17- Herceptin , Perjeta; july 14,2017,BMX,TE's,SNB,0/3;8/2017,Zoladex;1/26/2018,Arimidex
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May 31, 2017 05:13PM Suburbs wrote:

hi sportsmom. I avoided anti depressants for a few months but a couple of days of intermittent crying helped me realize that I needed the help. The multitude of treatments and steps one faces when triple positive make a tough journey even more difficult. I haven't taken them long enough to know if they are working but I am glad I started.

Dx 1/9/2017, DCIS/IDC, Right, 2cm, Stage IIA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ (IHC) Targeted Therapy 1/31/2017 Herceptin (trastuzumab) Chemotherapy 2/1/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 6/20/2017 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Hormonal Therapy 7/21/2017 Arimidex (anastrozole) Targeted Therapy 2/1/2018 Nerlynx

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