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All TopicsForum: HER2+ (Positive) Breast Cancer → Topic: TRIPLE POSITIVE GROUP

Topic: TRIPLE POSITIVE GROUP

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jan 31, 2011 06:30AM - edited Dec 10, 2012 07:55AM by TonLee

TonLee wrote:

This is primarily for people who find themselves with THREE +'s by their diagnosis. 

If you are new to breast cancer, please click on the link below and read.  It is "What I Wish I Knew At the Beginning of Treatment."

http://community.breastcancer.org/forum/6/topic/797454



IDC, 2cm, Stage IIIa, Grade 2, 4/4 nodes, ER+/PR+/HER2+, Skin Sparing uni-MX with TE, TCH, Rads Dx 9/14/2010, IDC, 2cm, Stage IIIA, Grade 2, 4/4 nodes, ER+/PR+, HER2+
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Jan 10, 2018 06:37PM moodyblues wrote:

Hap, thanks for the compliment. My hair is dark under with a heavy coating of grey on top, I have a skunk streak at the very top of my head that I should have posted.....I may still do that....it'll make you smile. I am sorry that you are having such a go with the treatments, I am positive that your anxiety makes you feel worse too. Worrying and stress isn't good for any of us and I know that you are terrified that there will be permanent damage. I hate that this isn't a good day for you, probably tomorrow will be better. ((hugs))

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 10, 2018 06:43PM moodyblues wrote:

Thanks Hap!

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 10, 2018 07:02PM Suburbs wrote:

Hi all. Moodyblues, bravo for having the courage to show your hair. I don't have your courage! But maybe I can share a laugh. My hair used to be long and straight. Now it is literally 2 inches long and the top stands straight up with the rest curly. If I put a headband around my head like Bjorn Borg, I look like an 80s music video. Think eye of the tiger. I can laugh again anyway.

cherry-sw, sorry to hear you are feeling bad but hurrah for finishing. The first month is worse and then it will get better. Hang in there. We're rooting for you.

HapB, I read your posts and struggle to think of anything to say that would be helpful. I have this image of you in my mind as a strong and fierce New Englander, a special type of person celebrated in books and movies. No one can bring a New Englander down. It's just not fitting. Here's to hoping you get your fighting spirit back and your treatment plan on track. Sending some mojo for you from the Mid-Atlantic.P.S. Your post helped to remind me to take my AI just now for which I thank you.

Dx 1/9/2017, DCIS/IDC, Right, 2cm, Stage IIA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ (IHC) Chemotherapy 2/1/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 2/1/2017 Herceptin (trastuzumab) Surgery 6/20/2017 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Hormonal Therapy 7/21/2017 Arimidex (anastrozole)
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Jan 10, 2018 07:19PM deni1661 wrote:

Hi girls, sorry I have been out of touch. Back at work FT after last surgery - 12+ hour days again. Yikes, this job and the stress that comes with it is not good. Good news is I am retiring in 11 weeks and 2 days. I have shoulder surgery in 2 weeks so I really don't have that many work days left. I shouldn't complain.

Hapb - thanks for posting the faster aging article. How true. My body feels like I am 80. I'm back to exercising again so maybe that will help. I fear what the AI is doing to my bones. And all the scans. That cannot be good for us. I had 7 scans in less than a year. I am sorry you are struggling with whether to take the AI. It must be especially difficult because you were off and felt so much better. The numbers don't make sense and this confuses me greatly. I am not in as much pain as you or have the heart issues but I empathize with how tough a decision this must be for you. I hope you can find peace in whatever you decide.

Melanie - you look great! Your smile is so warm and inviting. I'm happy your hair is coming back and really glad you are feeling so much better these days. Super news no BRCA, yay! 2018 will be your year for sure.

KimCee - yippee, you're at the finish line with the taxol! You have been endured so much going through BC twice. Your pity party of late is understandable.....feeling miserable and sick all the time not to mention the anxiety this stupid triple positive causes would impact any of us the same way. Maybe the AI is partly to blame? You are stronger than you give yourself credit for and I know you will move forward positively in the days ahead. Sending hugs your way :-)

Cherry - yippee, you're at the finish line too. I am so sorry you are feeling so terrible. I pray your medical team can find a way to give you relief. It may not seem like it now, but better days are ahead. Recovery is a slow process but as we've heard from Vicky, specialK, Melanie, myself and so many others here, we do find a new normal and brighter days are on the horizon. Sending you hugs too :-)

I think and pray for all of you daily even if I am not posting. I wish everyone a good rest of the week!
Dx 7/25/2016, IDC, Left, 2cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2+ (FISH) Targeted Therapy 9/6/2016 Perjeta (pertuzumab) Hormonal Therapy 9/6/2016 Arimidex (anastrozole) Targeted Therapy 9/6/2016 Herceptin (trastuzumab) Surgery 4/27/2017 Lymph node removal: Sentinel; Mastectomy: Left Surgery 5/9/2017 Reconstruction (left): Stacked DIEP flap
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Jan 10, 2018 07:38PM Cowgirl13 wrote:

Moody, I second what Hap said "your spirit shines through". What a lovely picture.

"Never miss a good chance to shut up."- Will Rogers Dx 5/28/2009, IDC, 2cm, Stage IIA, Grade 3, 0/4 nodes, ER+/PR+, HER2+
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Jan 10, 2018 08:04PM Taco1946 wrote:

About hair - mine came back very slowly after last taxol. It's curlier than it was and I think a little grayer (but I am 71). I stopped coloring it several years ago. A friend who had BC a number of years ago told me that she felt there were 2 full growth before she had her "now" hair.

Last Herceptin this Friday. I'm feeling very uneducated about what happens next other than the AI's. What questions should I be asking? I'm feeling superstitious about my port - if I keep it I won't need it and if I take it out, I will. Not having any trouble with it but getting it in was was painful and stressful. One year mammogram and visit to BS the end of the month.

I switched to femera from arimidex after 7 months. So far, doing better on it. Less joint pain and definitely fewer headaches. I also know keeping moving makes me feel better both physically and mentally. I can slide into being a couch potato too easily and that definitely affects my mood.

Dx 11/22/2016, IDC, Left, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2+ Radiation Therapy 12/29/2016 Balloon-catheter: Breast Chemotherapy 2/3/2017 Taxol (paclitaxel) Targeted Therapy 2/3/2017 Herceptin (trastuzumab) Hormonal Therapy 12/4/2017 Femara (letrozole) Targeted Therapy Surgery Lumpectomy: Left; Lymph node removal: Sentinel, Underarm/Axillary
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Jan 10, 2018 09:06PM KimCee wrote:

Melanie! You look super duper awesome! Love your new growth. Your head is covered, yippee.

Vicky...my bud. Thank you for your pep talk always. I did not know you were battling this aspect too. Glad you have it under control for the most part. And your hair is way cool too. I love it.

Deni aw thanks for the kind words. I kind of know I am strong, I have to be, but the meltdowns do happen. Taxol ends tomorrow, thank goodness, I am so over done.

Taco, I did super great on Femara, glad you are feeling better. Wish I could do Femara again. And congratulations on last Herceptin...can't wait to post that myself.

Dx 8/10/1999, IDC, Right, 1cm, Stage IA, Grade 1, 0/4 nodes, ER+/PR+, HER2- Surgery 8/24/1999 Lumpectomy: Right; Lymph node removal: Sentinel Chemotherapy 9/8/1999 AT Radiation Therapy 1/4/2000 Whole-breast: Breast Dx 7/31/2017, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ Surgery 9/26/2017 Lymph node removal: Sentinel; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 10/25/2017 Taxol (paclitaxel) Targeted Therapy Herceptin (trastuzumab) Hormonal Therapy Femara (letrozole), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone), Zoladex (goserelin)
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Jan 10, 2018 09:38PM SpecialK wrote:

hap - hang in there

moody - you look great

kim - don't judge how you look right now - treatment takes a toll, things will improve later

cherry - start the Claritin the day before, keep taking it for a minimum of several days - take this study info to your docs:

https://clinicaltrials.gov/ct2/show/NCT01712009

https://www.ncbi.nlm.nih.gov/pubmed/24664474

https://www.practicalpainmanagement.com/treatments/pharmacological/non-opioids/antihistamine-g-csf-induced-bone-pain

BMX w/ TE 11/1/10, ALND 12/6/10. 14 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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Jan 10, 2018 10:18PM whywhy wrote:

Seeking advice. Has anyone decided to do mastectomy after lumpectomy/chemo. Did my lumpectomy in a hurry after diagnoses. In chemo now. Always wondered if I should have chosen mastectomy (no rebuild) instead. Don't know if I can still do it after the chemo. I saw so many people opts for mastectomy. I just turned forty five at diagnosis time. Desperately want to live long enough (at least another eight years) to see daughter get into college.

Dx 11/1/2017, IDC, Left, 2cm, Stage IIA, Grade 3, 0/3 nodes, ER+/PR+, HER2+ (FISH) Surgery 11/16/2017 Lumpectomy: Left Chemotherapy 12/13/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 12/13/2017 Perjeta (pertuzumab) Targeted Therapy 12/13/2017 Herceptin (trastuzumab)
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Jan 10, 2018 10:24PM HapB wrote:

whywhy, did your doctors tell you that your chances cor survival would be improved with a mastectomy? I know how you feel about your daughter and the worries. For now, it might be better for you just to focus on getting through this treatment and taking care of yourself and your daughter. It is my understanding that the stats don’t show a difference in early stage BC and they save the breast if they can. Keep the faith!

Dx 4/2017, IDC, Right, 1cm, Stage IA, Grade 2, ER+/PR+, HER2+ (FISH) Surgery 5/10/2017 Lumpectomy: Right Targeted Therapy 6/8/2017 Herceptin (trastuzumab) Hormonal Therapy Radiation Therapy
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Jan 11, 2018 12:32AM SpecialK wrote:

whywhy - here are some links to study data that show that Her2+ patients potentially have a greater risk of loco-regional recurrence following lumpectomy than mastectomy. Across the board for early stagers of all subtypes lumpectomy plus radiation generally equals mastectomy in terms of OS (overall survival), but for the same population, not factoring subtype, lumpectomy plus radiation carries a slightly higher risk of local recurrence than mastectomy so they are not equal as far as DFS (disease free survival) goes.

https://www.hindawi.com/journals/isrn/2013/290568/

https://link.springer.com/article/10.1007/s10549-011-1891-6

BMX w/ TE 11/1/10, ALND 12/6/10. 14 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC) Dx 9/27/2010, DCIS, Stage 0, Grade 3
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Jan 11, 2018 01:43AM - edited Jan 11, 2018 02:21AM by red332

Has anyone taken (or is taking now) beta glucans in conjunction with herceptin? The integrative medicine doc at my hospital recommended it based on some preliminary studies of mice (and one of colon cancer patients). But I am having a hard time finding a high quality brand and dosing guidelines. Doc recommended a mass market brand.

I did just find a study that suggests that yeast-based beta glucans are better for this purpose than mushroom based ones, so that helps narrow it down. https://www.ncbi.nlm.nih.gov/pubmed/19106638

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Jan 11, 2018 01:47AM red332 wrote:

Special K, how much weight do you think should be put on the recent taxol/herceptin study (7 year follow up so far) which shows a very low local recurrence rate (something like 1.2%)? is the study large enough to be significant in this decisionmaking? (I am also trying to decide whether to have a BMX after chemo).

Also, in the study you cite above, only a small % of Her2+ patients received herceptin. Wondering how to account for that in analyzing the data here.

Any thoughts?

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Jan 11, 2018 03:05AM Cherry-sw wrote:

SpecialK, thank you, I am sorry about your MIL, hope you will all have a quite and beautiful memorial. I will read the studies too.

Overall this EC sucks and I feel I will be down for quite a while but will have rads simulation with CT-scans tomorrow, not looking forward at all.

moodyblues, you look great and so much hair growth in such a short time. My hair are still very sparse but I have new eyebrows and lashes, very short but growing

Dx 6/28/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/3 nodes, ER+/PR+, HER2+ Surgery 7/18/2017 Lumpectomy: Left Targeted Therapy 8/21/2017 Herceptin (trastuzumab) Chemotherapy 8/21/2017 Taxol (paclitaxel)
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Jan 11, 2018 07:57AM whywhy wrote:

HapB, SpecialK, Thanks for the notes and the links to the research. Surgeon told me the difference between lumpectomy/radiation vs BMX is small. Lumpectomy did allow me to recover very quickly and function as a mom. Now just thought if there is anything else I could do to reduce the risks a little bit more. I guess it's the human nature to control the uncontrollable. I'll ask my oncologist when I see him again. For BMX, I am also a bit worried about the length to recovery and the potential impact to holding on to my job.

Dx 11/1/2017, IDC, Left, 2cm, Stage IIA, Grade 3, 0/3 nodes, ER+/PR+, HER2+ (FISH) Surgery 11/16/2017 Lumpectomy: Left Chemotherapy 12/13/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 12/13/2017 Perjeta (pertuzumab) Targeted Therapy 12/13/2017 Herceptin (trastuzumab)
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Jan 11, 2018 08:03AM HapB wrote:

special, thanks for the links. Nobody ever told me that there was a greater risk with lumpectomy and rads. My surgeon and Mo told me it was the same. Grrrr. So hard to know the facts with this BC

Dx 4/2017, IDC, Right, 1cm, Stage IA, Grade 2, ER+/PR+, HER2+ (FISH) Surgery 5/10/2017 Lumpectomy: Right Targeted Therapy 6/8/2017 Herceptin (trastuzumab) Hormonal Therapy Radiation Therapy
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Jan 11, 2018 08:39AM moodyblues wrote:

SpecialK, Thanks for the links. I've only read the first link and it was VERY informative and interesting. Some of it was over my head but many points hit home. I am looking forward to the second link later.

If Resveratrol is so amazing, why aren't we all on it? The doctors don't even mention this. It was listed under the Aromatase Inhibitors section where it said: Interestingly, natural anticancer agents such as resveratrol with documented anticancer property [156, 157] are natural aromatase inhibitors [158].

Bisphosphonates. Under this section (second paragraph) I was totally questioning why the doctors don't mention this to us? For us HER2 ladies it could mean lessening the chance of recurrence in our bones.

The Natural Compounds section was informative as well and I will be looking into the natural anticancer agents such as curcumin, sulforaphane, isoflavones, EGCG, and resveratrol. Not sure about the isoflavones with me being ER+ though.

I have a lot to digest and will to read it again later as I have read it several times already. Thanks again for posting this for us!

Melanie

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 11, 2018 08:45AM moodyblues wrote:

Thanks everyone for the kind comments on my hair. I know it's not long at all but, I am so happy to have some hair now! It sure beats being bald especially in this frigid weather!

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 11, 2018 09:41AM Jumpship wrote:

I am very curious about the circulating tumor cells. Anyone been successful in getting a doc to test those

Negative for 16 of 17 gene markers. Positive for NBN-marker of unknown significance. Dx 7/2/2014, IDC, Left, 2cm, Stage IIA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ (FISH) Surgery 9/29/2014 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 11/20/2014 Herceptin (trastuzumab) Chemotherapy 11/20/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 11, 2018 09:44AM ElaineTherese wrote:

whywhy,

I decided to just go with a lumpectomy, even though I knew that there's a greater chance of local recurrence with a lumpectomy. I didn't want to do reconstruction or go flat. I figure that if I do get a local recurrence, my surgeon can do an MX then. You can always get more taken off later, but once your boobs are gone, they're gone.

Since I did the lumpectomy, I've also appreciated that I get more monitoring than I would have if I'd chosen a BMX. Three years out, I still see my MO every three months, and she gives me a physical exam. Also,some women hate getting mammos, but I don't mind them because they have continued to show that nothing's going on in my boobs. Besides, if I did have a local recurrence, I'd want to know immediately.

So, I'm at peace with my decision.

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/23/2014 AC Targeted Therapy 9/17/2014 Perjeta (pertuzumab) Targeted Therapy 9/17/2014 Herceptin (trastuzumab) Chemotherapy 9/17/2014 Taxol (paclitaxel) Surgery 1/12/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/25/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/9/2015 Breast, Lymph nodes
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Jan 11, 2018 08:46PM whywhy wrote:

ElaineTherese, Thanks for sharing your experience!

Dx 11/1/2017, IDC, Left, 2cm, Stage IIA, Grade 3, 0/3 nodes, ER+/PR+, HER2+ (FISH) Surgery 11/16/2017 Lumpectomy: Left Chemotherapy 12/13/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 12/13/2017 Perjeta (pertuzumab) Targeted Therapy 12/13/2017 Herceptin (trastuzumab)
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Jan 11, 2018 09:01PM willa216 wrote:

Hello All and Happy New Year!

I haven't been here in quite some time but think of you all often.

This is superficial perhaps, relative to some other current questions, but is anybody experiencing a bit of a receding hairline on Tamoxifen? I finished chemo about 15 months ago. I used cold caps and kept about 50% of my hair. It grew back normally and thick. Now after a year on Tamoxifen I'm suddenly noticing changes along my hairline, with shorter less dense hair at temples . My imagination is getting the best of me and I'm envisioning myself in five years ( or 6 months!) with full on male pattern baldness. Not cool. I know hair loss is a side effect (5%) of Tamoxifen but I had always interpreted it as overall thinning. Wondering if anyone has had this. I'm worried. Esp because of all the effects of blocking estrogen where we'd like to have it.

Thank you. Much love and best wishes for a joyful and healthy 2018.




IDC; 2cm; 0/4 nodes; ER+ PR+ HER2+; UMX and reconstruction July 2016; Taxol , Carboplatin, Perjeta, Herceptin 12x/weekly August 2016; Herceptin through Aug 2017
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Jan 11, 2018 09:13PM - edited Jan 11, 2018 09:13PM by HapB

Hi Willa, I have a clise friend who was on Tamoxifen about 10 years ago and she is doing great now. However, she did have male pattern baldness and severe thinning and had to wear a wig for about 4 years. She had hardly any hair left and gained about 30 pounds, but now she looks fantastic!

Dx 4/2017, IDC, Right, 1cm, Stage IA, Grade 2, ER+/PR+, HER2+ (FISH) Surgery 5/10/2017 Lumpectomy: Right Targeted Therapy 6/8/2017 Herceptin (trastuzumab) Hormonal Therapy Radiation Therapy
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Jan 12, 2018 06:12AM coachvicky wrote:

All,

My husband and I spent Wednesday at a local hospital. A friend was just diagnosed and had her lumpectomy on Wednesday. We went to sit with her husband. A friend of ours just showed up at my surgery to sit with my husband.

I must have gotten really old looking. The staff member at the hospital desk invited us to go back when the surgery was over. I think she thought we were the parents. LOL

This friend is the one that made my buttons and key chain saying "my chemo rocks." She did other things to support us as well.

I guess what I am dealing with is how wide spread BC is. I never knew until it happened to me. At least now we know what to do for others.

Vicky


Dx 6/2016, DCIS/IDC, Both breasts, Stage IIA, Grade 3, ER+/PR+, HER2+ (FISH) Dx 6/7/2016, LCIS/DCIS/IDC, Right, 4cm, Stage IIA, Grade 3, ER+/PR+, HER2+ (FISH) Surgery 7/11/2016 Mastectomy; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 8/21/2016 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 8/22/2016 Herceptin (trastuzumab) Surgery 1/20/2017 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Surgery 2/22/2017 Prophylactic ovary removal Hormonal Therapy 4/4/2017 Arimidex (anastrozole)
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Jan 12, 2018 09:15AM moodyblues wrote:

Vicky, yes I am amazed as well at how wide spread it is. Remember my post about the three of us at Dollar Tree in the same aisle, same day, same time? How crazy is that? I found out several months ago that a coworker that I had worked with for years, had breast cancer and is still currently on estrogen blockers, I never knew.

By the way, you do not look old, you look pretty darn hot to me! ;)

Melanie

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 12, 2018 09:43AM coachvicky wrote:

Thanks Melanie ...you made me laugh!

Vicky

Dx 6/2016, DCIS/IDC, Both breasts, Stage IIA, Grade 3, ER+/PR+, HER2+ (FISH) Dx 6/7/2016, LCIS/DCIS/IDC, Right, 4cm, Stage IIA, Grade 3, ER+/PR+, HER2+ (FISH) Surgery 7/11/2016 Mastectomy; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 8/21/2016 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 8/22/2016 Herceptin (trastuzumab) Surgery 1/20/2017 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Surgery 2/22/2017 Prophylactic ovary removal Hormonal Therapy 4/4/2017 Arimidex (anastrozole)
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Jan 12, 2018 01:24PM moodyblues wrote:

Loopy Glad that I could make you smile Vicky!

Dx 2/2017, IDC, Left, 2cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 3/31/2017 Lymph node removal: Sentinel; Mastectomy: Left; Reconstruction (left): Silicone implant Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 12, 2018 05:11PM rljes wrote:

Hi All...  Chemo #3/ Day 4   (chemo 3 of 6)

Constipated, bloated, fatigue, taking Urea for cracked hurting feet and just plain exhausted.....


I'm confused (chemo Brain)  what is the difference between taking Tamoxifen and an AI ?  I thought they were all estrogen blockers. ???? The same thing? 

My MO hasn't mentioned any type of estrogen blocker yet.  

Hope everyone is hanging in there... I'll read your article HapB later when I can concentrate - will catch up in a bit. 


*Started Chemo 11/28/17 / No recontruction - going flat /Neulasta Injection Pod Dx 6/26/2017, IDC, Left, 3cm, Stage IIB, Grade 2, ER+/PR+ Dx 8/22/2017, 1/7 nodes, HER2+ Surgery 8/22/2017 Mastectomy: Left, Right Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 12, 2018 06:36PM HapB wrote:

rjes, hang in there. Tamoxifen is given if you are estrogen positive and premenopausal and the AI’s are given if you are postmenopausal. I hope you have a peaceful and painfree weekend.

Dx 4/2017, IDC, Right, 1cm, Stage IA, Grade 2, ER+/PR+, HER2+ (FISH) Surgery 5/10/2017 Lumpectomy: Right Targeted Therapy 6/8/2017 Herceptin (trastuzumab) Hormonal Therapy Radiation Therapy
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Jan 12, 2018 07:16PM whywhy wrote:

What's the definition of pre/postmenopausal? I am premenopausal before chemo. My oncologist said that it's unlikely my ovary would survive chemo at my age(45). 2-3 round of chemo probably would destroy it. Not sure in my case would I be considered pre or post. Read some side effects on tamoxifen and it looks pretty tough with side effects. Looks like AI has less side effects.

Dx 11/1/2017, IDC, Left, 2cm, Stage IIA, Grade 3, 0/3 nodes, ER+/PR+, HER2+ (FISH) Surgery 11/16/2017 Lumpectomy: Left Chemotherapy 12/13/2017 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 12/13/2017 Perjeta (pertuzumab) Targeted Therapy 12/13/2017 Herceptin (trastuzumab)

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