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Jan 10, 2021 10:58AM
Jan 10, 2021 11:03AM
i sigged up to participate in this Phase 2 Clinical Trial. I really like the idea of using vaccines to train the immune system to recognize and attack cancer cells.
It's a 2 ARM trial, no Placebo group, i will get a vaccine either way.
There are 2 outstanding questions, one pertains to travel vaccines (I'm supposed to go to Africa in August 🤞🏻), the other is if I can start Nerlynx during the trial or if I have to wait until all boosters are completed (12 months).
For those that have done Nerlynx or vaccine trials or both, what are your thoughts on delaying Nerlynx for 1 year? I looked and, I can start Nerlynx within 2 years of surgery which would be June 2022. So I'll have time since the vaccine portion of the trial should finish March/April 2022.
However, I am a little worried about the delay. Nerlynx has a known benefit, anywhere from 2-5% risk reduction. The Vaccine is unknown but, could have as good or maybe even better results.
Any thoughts or suggestions?
ETA: Per the Dr running the trial in NJ, these vaccines target HER2+ cells/expression because they believe that this is the primary driver even for Triple+. I know that's still a question as to what drives our cancer since we're a sub-category of HER2+ BC.
1/20/2020, DCIS/IDC, Right, 4cm, Stage IIA, Grade 2, ER+/PR+, HER2+ (IHC)
2/5/2020 Carboplatin (Paraplatin), Taxotere (docetaxel)
2/5/2020 Herceptin (trastuzumab)
2/5/2020 Perjeta (pertuzumab)
6/19/2020, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 1/3 nodes, ER+/PR+, HER2+
6/19/2020 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement
7/6/2020 Kadcyla (T-DM1, ado-trastuzumab)
8/10/2020 Whole-breast: Breast, Lymph nodes, Chest wall