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Topic: TRIPLE POSITIVE GROUP

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jan 31, 2011 07:30AM - edited Dec 10, 2012 08:55AM by TonLee

TonLee wrote:

This is primarily for people who find themselves with THREE +'s by their diagnosis. 

If you are new to breast cancer, please click on the link below and read.  It is "What I Wish I Knew At the Beginning of Treatment."

http://community.breastcancer.org/forum/6/topic/797454



IDC, 2cm, Stage IIIa, Grade 2, 4/4 nodes, ER+/PR+/HER2+, Skin Sparing uni-MX with TE, TCH, Rads Dx 9/14/2010, IDC, 2cm, Stage IIIA, Grade 2, 4/4 nodes, ER+/PR+, HER2+
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Jan 21, 2021 12:14PM - edited Jan 21, 2021 12:16PM by morrigan_2575

My mother has pin-point spots on her lungs (found same time they found a tumor on her kidney - happy accident). She gets a CT every year for the last 5 years to make sure they don't grow. They're almost certain it's a result of pneumonia but, they keep an eye on it to be safe

Dx 1/20/2020, DCIS/IDC, Right, 4cm, Stage IIA, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/4/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 2/4/2020 Herceptin (trastuzumab) Targeted Therapy 2/4/2020 Perjeta (pertuzumab) Surgery 6/18/2020 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 6/19/2020, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 1/3 nodes, ER+/PR+, HER2+ Targeted Therapy 7/5/2020 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 8/9/2020 Whole-breast: Breast, Lymph nodes, Chest wall
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Jan 21, 2021 12:34PM Redcanoe wrote:

Oh yes the oncologist also confirmed officially that the rest of my chemo can be done locally and I have no scheduled medical travel or isolations hopefully until radiation. That is going to be tough but at least I'll have lots of time to prepare myself and the kids. Maybe I'll find a way to bring them with me.

Toni - age 34, mom to 4 kids ages 11, 8, 5 and 3 Dx 11/19/2020, DCIS/IDC, Right, 2cm, Stage IIB, Grade 3, 2/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 12/14/2020 Lumpectomy: Right Chemotherapy 1/11/2021 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 1/11/2021 Herceptin (trastuzumab)
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Jan 26, 2021 08:45PM Jumpship wrote:

BCI the Breast Cancer Index looked like it had some findings presented at San Antonio in December. Is this a tool that +++ can use to see if we really need an extra 5 years of the AIs?

Negative for 16 of 17 gene markers. Positive for NBN-marker of unknown significance. Dx 7/2/2014, IDC, Left, 2cm, Stage IIA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ (FISH) Surgery 9/29/2014 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 11/20/2014 Herceptin (trastuzumab) Chemotherapy 11/20/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jan 26, 2021 11:20PM SpecialK wrote:

jumpship - here is a link to BCI testing and results for ER+/Her2+ patients. My read on the results is that a higher percentage of Her2+ patients that have this test done do fall into the higher risk of late recurrence category, but more also seem to benefit from extended use of anti-hormonal therapy than ER+/Her2- patients. I had the BCI test done at the five year point and unfortunately fell into the 10% of testers who had high risk of recurrence, but low benefit of extended anti-hormonal therapy. My oncologist did encourage me to continue if I could handle the side effects and I completed 7.5 years.

https://ascopubs.org/doi/abs/10.1200/jco.2015.33.15_suppl.595


BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, DCIS, Stage 0, Grade 3 Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC)
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Jan 29, 2021 11:03AM Nsbrown54 wrote:

I just had my 2nd HP treatment. The first one was only herceptin (kajinti). I had no side effects. I woke up fine this morning but am getting more lethargic as the day progresses. Is this normal? Are the HP treatments cumulative like TCHP? Other than being a little anemic my blood work is fine

Dx 6/22/2020, IDC, Right, 6cm+, Stage IIB, ER+/PR+, HER2+ Chemotherapy 6/29/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 11/19/2020 Mastectomy Hormonal Therapy 12/8/2020 Femara (letrozole) Targeted Therapy 1/4/2021 Herceptin (trastuzumab) Targeted Therapy 1/26/2021 Perjeta (pertuzumab)
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Jan 29, 2021 04:01PM AngelsGal57 wrote:

Well, I have had to shave my head to 1/4 inch long due to hair loss. My sister in law did it for me and said there was noticeable hair regrowth already. My last treatment of the 6 rounds of Enhertu is on Feb 4th and we shall see what my cancer markers are telling us. The last number was 14 so we shall see if it has continued to go down.

Angelsgal

Dx 3/20/2017, Right, 4cm, Stage IIA, metastasized to bone/lungs, Grade 2, 0/2 nodes, ER+/PR+, HER2+ Surgery 10/4/2017 Lumpectomy: Right; Lymph node removal: Sentinel Radiation Therapy 11/14/2017 Whole-breast: Breast Hormonal Therapy 7/4/2018 Arimidex (anastrozole), Aromasin (exemestane), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy Arimidex (anastrozole), Aromasin (exemestane), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Targeted Therapy Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab) Chemotherapy Other
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Jan 29, 2021 04:37PM Redcanoe wrote:

Thanks for the update angelsgal. Sounds very positive!


I just shaved my hair today too. I have my second round of TCH on Tuesday and hair started coming out on Wednesday evening.

Toni - age 34, mom to 4 kids ages 11, 8, 5 and 3 Dx 11/19/2020, DCIS/IDC, Right, 2cm, Stage IIB, Grade 3, 2/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 12/14/2020 Lumpectomy: Right Chemotherapy 1/11/2021 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 1/11/2021 Herceptin (trastuzumab)
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Jan 29, 2021 10:03PM MsMurphy wrote:

I shaved my head a few weeks ago and have been excited to have some growth coming back lately. I mentioned it to the oncologist today and he burst my excitement bubble by telling me to not be surprised if it falls back out/regrows again until chemo is done.

Dx 8/27/2020, DCIS/IDC, Left, 1cm, Stage IB, Grade 3, ER+/PR+, HER2+ (IHC) Surgery 9/23/2020 Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 12/17/2020 Herceptin (trastuzumab) Chemotherapy 12/17/2020 Carboplatin (Paraplatin), Taxol (paclitaxel) Hormonal Therapy
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Jan 29, 2021 11:27PM Redcanoe wrote:

I'm getting my covid-19 vax tomorrow. My oncologist really wants me to get it. It will be three days before my second dose of TCH

Toni - age 34, mom to 4 kids ages 11, 8, 5 and 3 Dx 11/19/2020, DCIS/IDC, Right, 2cm, Stage IIB, Grade 3, 2/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 12/14/2020 Lumpectomy: Right Chemotherapy 1/11/2021 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 1/11/2021 Herceptin (trastuzumab)
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Jan 30, 2021 11:01AM - edited Jan 30, 2021 11:02AM by morrigan_2575

congrats on having the opportunity! I can't get any appointment (all booked). Thankfully I was able to get my mom one in her county

Dx 1/20/2020, DCIS/IDC, Right, 4cm, Stage IIA, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/4/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 2/4/2020 Herceptin (trastuzumab) Targeted Therapy 2/4/2020 Perjeta (pertuzumab) Surgery 6/18/2020 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 6/19/2020, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 1/3 nodes, ER+/PR+, HER2+ Targeted Therapy 7/5/2020 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 8/9/2020 Whole-breast: Breast, Lymph nodes, Chest wall
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Jan 30, 2021 12:46PM ElaineTherese wrote:

morrigan,

My sister's in-laws in New Jersey have been having the same problem. Thankfully, my parents live in Connecticut, so they've already gotten Dose #1 of the Moderna vaccine.

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/22/2014 AC Targeted Therapy 9/16/2014 Perjeta (pertuzumab) Targeted Therapy 9/16/2014 Herceptin (trastuzumab) Chemotherapy 9/16/2014 Taxol (paclitaxel) Surgery 1/11/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/24/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/8/2015 Breast, Lymph nodes
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Jan 30, 2021 04:41PM - edited Feb 2, 2021 08:44AM by MsMurphy

I got my first shot of the vaccine last Monday. Very lucky as my employer got approval since we employ home health caregivers which puts all of us in the office at risk. My arm was a little sore for a day and I felt even more tired than usual but that was it. Hope you all get yours soon.

Dx 8/27/2020, DCIS/IDC, Left, 1cm, Stage IB, Grade 3, ER+/PR+, HER2+ (IHC) Surgery 9/23/2020 Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 12/17/2020 Herceptin (trastuzumab) Chemotherapy 12/17/2020 Carboplatin (Paraplatin), Taxol (paclitaxel) Hormonal Therapy
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Feb 1, 2021 05:02PM Redcanoe wrote:

I am pretty upset. Round two of TCH is tomorrow and my ALT went from 22 to 136 since first round. My taxotere is being reduced by 20%. Has this happened to anyone? What happens if I cant tolerate the taxotere?

Toni - age 34, mom to 4 kids ages 11, 8, 5 and 3 Dx 11/19/2020, DCIS/IDC, Right, 2cm, Stage IIB, Grade 3, 2/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 12/14/2020 Lumpectomy: Right Chemotherapy 1/11/2021 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 1/11/2021 Herceptin (trastuzumab)
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Feb 1, 2021 05:12PM SpecialK wrote:

redcanoe - dose reductions are pretty common, try not to stress. Taxotere is a fairly intense drug, so there is the possibility you can be switched to Taxol if your liver values continue to be impacted. Something to consider is that the first infusion contains loading doses, which are larger than the subsequent ones. Your liver values may stabilize and not continue to drop further since the dose will be smaller and also reduced by a percentage. It is also not uncommon to have fluctuation in liver values - chemotherapeutic drugs are either filtered by the kidneys or the liver, depending on the drug. This is why function of these organs is checked throughout chemo, and most oncologists expect to see these changes. The approach if there is concern about too big a change is to do exactly what your MO did though - reduce the dose and see how you do. Hang in there.

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, DCIS, Stage 0, Grade 3 Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC)
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Feb 1, 2021 05:43PM Redcanoe wrote:

thank you specialk. I will try not to worry and hope it resolves before round three.

Toni - age 34, mom to 4 kids ages 11, 8, 5 and 3 Dx 11/19/2020, DCIS/IDC, Right, 2cm, Stage IIB, Grade 3, 2/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 12/14/2020 Lumpectomy: Right Chemotherapy 1/11/2021 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 1/11/2021 Herceptin (trastuzumab)
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Feb 1, 2021 08:53PM morrigan_2575 wrote:

My MO dropped my Carboplatin by 10% for TCHP #5 but, I went back to full dose to finish the treatment.


Dx 1/20/2020, DCIS/IDC, Right, 4cm, Stage IIA, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/4/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 2/4/2020 Herceptin (trastuzumab) Targeted Therapy 2/4/2020 Perjeta (pertuzumab) Surgery 6/18/2020 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 6/19/2020, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 1/3 nodes, ER+/PR+, HER2+ Targeted Therapy 7/5/2020 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 8/9/2020 Whole-breast: Breast, Lymph nodes, Chest wall
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Feb 2, 2021 06:27AM YesIamaDragon wrote:

I am sorry you had to get it as shots! That is why I love my port, even though so many people hate them. I just don't want to be poked so much!

Dx 6/2019, IDC, Right, 2cm, Grade 2, ER+/PR+, HER2+ Hormonal Therapy Arimidex (anastrozole) Radiation Therapy Targeted Therapy Kadcyla (T-DM1, ado-trastuzumab) Surgery Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy Perjeta (pertuzumab) Targeted Therapy Herceptin (trastuzumab)
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Feb 11, 2021 12:54PM idkwhatsnext wrote:

I finished my 6 doses of TCHP and I'm getting my first dose of just HP today. Does anyone still recommend icing your hands/feet because of the neuropathy that Perjeta has caused for some? I'm assuming not since I can't find anything about it. Also, has anyone's MO continued to prescribe Neulasta for the Herceptin?

Dx 8/27/2020, IDC, Left, 5+cm, Multifocal + Calc, Stage?, ER+/PR+, HER2++, Grade 3 Targeted Therapy 10/9/2020 Herceptin (trastuzumab) Targeted Therapy 10/9/2020 Perjeta (pertuzumab) Chemotherapy 10/9/2020 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Feb 11, 2021 12:57PM - edited Feb 11, 2021 12:57PM by LaughingGull

No Neulasta with the Herceptin/Perjeta combo

ACx4, THPx4, HP (to complete 1y); Nerlynx (1y); AI (expected 10y), Surgery: BMX + ALND, Reconstruction, Oophorectomy. Radiation. Dx 10/26/2017, IDC, Right, 3cm, Stage IIB, Grade 3, 2/6 nodes, ER+/PR+, HER2+ (IHC)
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Feb 11, 2021 01:12PM Nsbrown54 wrote:

LaughingGull - that’s been my experience. No additional IV or oral meds at all. Yippee

Dx 6/22/2020, IDC, Right, 6cm+, Stage IIB, ER+/PR+, HER2+ Chemotherapy 6/29/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 11/19/2020 Mastectomy Hormonal Therapy 12/8/2020 Femara (letrozole) Targeted Therapy 1/4/2021 Herceptin (trastuzumab) Targeted Therapy 1/26/2021 Perjeta (pertuzumab)
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Feb 13, 2021 11:50PM Jumpship wrote:

Has anyone chosen to have ovaries removed for fear of ovarian cancer? I have no genetic markers but 1 aunt who died from it. The closer to her age I get the more I fear it. Then I think -why remove another body part

Negative for 16 of 17 gene markers. Positive for NBN-marker of unknown significance. Dx 7/2/2014, IDC, Left, 2cm, Stage IIA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ (FISH) Surgery 9/29/2014 Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Targeted Therapy 11/20/2014 Herceptin (trastuzumab) Chemotherapy 11/20/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Feb 15, 2021 08:35PM LaughingGull wrote:

Hi Jumpship,

I had my ovaries removed and I feel it was the right decision for me. Many things to consider for the ovary removal. Fear alone, not enough of a reason.

Did you discuss your ovarian cancer risk with your oncologist, or, better yet, with a gynecologist-oncologist?

My dad died when he was 46 (not cancer), and I recall going through death fears every time anyone in my close family (including myself) reached that age -good thing we all left that milestone behind 😀 so I think I understand -but you really need to look into your risk and pros and cons.

LaughingGull

ACx4, THPx4, HP (to complete 1y); Nerlynx (1y); AI (expected 10y), Surgery: BMX + ALND, Reconstruction, Oophorectomy. Radiation. Dx 10/26/2017, IDC, Right, 3cm, Stage IIB, Grade 3, 2/6 nodes, ER+/PR+, HER2+ (IHC)
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Feb 17, 2021 12:50PM SpecialK wrote:

jumpship - I had a total abdominal hyst/ooph nine years before I was diagnosed with breast cancer - I had uterine fibroids too numerous to count that were causing havoc and endless bleeding. When I had the surgical consult the gyn surgeon recommended removing my ovaries since I was 45 and had many ovarian cysts over the years as well. Everyone was surprised at the surgical pathology when they found a 3cm pre-malignant tumor in the right ovary, never seen on the TVUS done within 6 months prior to the surgery. So... the surgery was definitely the right call for me and now knowing how strongly estrogen fed my breast cancer I would think I might have been diagnosed at a younger age had I left the ovaries in place. Of course, it didn't prevent my BC, but I was glad to be able to go straight to an aromatase inhibitor as that is what my MO prefers for his triple positive patients.

BMX w/ TE 11/1/10, ALND 12/6/10. 15 additional surgeries. TCHx6 2/17-6/2/11. Herceptin until 1/19/12. Femara 8/1/11, Arimidex 6/20/12, back to Femara 6/18/13-present. Dx 9/27/2010, DCIS, Stage 0, Grade 3 Dx 9/27/2010, IDC, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ (IHC)
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Feb 17, 2021 02:13PM morrigan_2575 wrote:

i haven't had my period since January 2020. I asked my MO to check my Estrogen but, he wants to wait until I'm done with Kadcyla (April).

However, I'm trying to get into this vaccine trial and they wanted to know (very paranoid about pregnancy). So they tested me and I am in full menopause. I have no idea if this will change after Kadcyla ends but, it does give me options...going to AI without Lupron. Possibly more time to make any surgical decisions.

Dx 1/20/2020, DCIS/IDC, Right, 4cm, Stage IIA, Grade 2, ER+/PR+, HER2+ (IHC) Chemotherapy 2/4/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Targeted Therapy 2/4/2020 Herceptin (trastuzumab) Targeted Therapy 2/4/2020 Perjeta (pertuzumab) Surgery 6/18/2020 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 6/19/2020, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 1/3 nodes, ER+/PR+, HER2+ Targeted Therapy 7/5/2020 Kadcyla (T-DM1, ado-trastuzumab) Radiation Therapy 8/9/2020 Whole-breast: Breast, Lymph nodes, Chest wall
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Feb 20, 2021 09:42AM Maskwearer72 wrote:

Nsbrown54 - in my experience Herceptin did not come with any cumulative side effects. I felt 100% normal after about half of my infusions and the other half just left me a little tired for the day of the infusion. Totally fine the next day. For one infusion I didn't eat anything prior and that day I felt a little blah but nothing compared to chemo. I just had my last infusion this week. Port gets removed Monday. Keep going - you'll get through this!

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Feb 20, 2021 07:43PM dlr68 wrote:

Hi. If there is anyone out there that had a unilateral mastectomy for DCIS/IDC stage 2 triple positive with chemo and HP, did your surgeon or oncologist wait 6 months or a year to check the other breast with a mammogram? Thanks

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Feb 22, 2021 11:16AM Nsbrown54 wrote:

dlr68 - I see my breast doctor Wednesday for the first time since my mastectomy. I expect that she’ll get me scheduled for a mammogram and/or ultrasound of my remaining breast. My last round of testing was in June when I was being diagnosed, so it’s well past time. I was previously having yearly mammogram and breast MRI done 6 months apart.

Dx 6/22/2020, IDC, Right, 6cm+, Stage IIB, ER+/PR+, HER2+ Chemotherapy 6/29/2020 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 11/19/2020 Mastectomy Hormonal Therapy 12/8/2020 Femara (letrozole) Targeted Therapy 1/4/2021 Herceptin (trastuzumab) Targeted Therapy 1/26/2021 Perjeta (pertuzumab)
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Feb 22, 2021 02:07PM Iamloved wrote:

I am sure there is a thread somewhere on this but would like to ask all of the triple positives if any opted to not take anti hormone drugs. At my age (soon to be 61) I am interested in quality of life. I have a history of psoriatic arthritis, depression and anxiety yoyo weight losses and gains. Menopause sucked for years. My psoriatic arthritis is managed with my naturopathic dr and the last 2 years intermittent fasting and keto have helped me maintain my weight loss. I dont want my next 5 to 10 years make me feel like I am 80 years old. Advice from all would be welcomed! 🤗

Surgery December 1 2020 Lumpectomy and oncoplastic surgery Dx 8/8/2018, IDC, Right, 2cm, Stage IIB, Grade 3, 0/3 nodes, ER+/PR+, HER2+ (IHC) Surgery 8/30/2018 Lumpectomy: Right; Lymph node removal: Sentinel Dx 5/14/2020, IDC, Right, 6cm+, Stage IIB, Grade 3, 0/2 nodes, ER+/PR+, HER2+ (IHC) Targeted Therapy 7/14/2020 Herceptin (trastuzumab) Chemotherapy 7/14/2020 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Feb 22, 2021 04:18PM ElaineTherese wrote:

Iamloved,

There are a zillion threads about whether or not to take hormonal therapy. I'm on Year 6 of exemestane (generic Aromasin). I don't feel like I'm 80. It initially gave me hot flashes and moodiness, but the moodiness resolved with Celexa, and the hot flashes resolved with time. It gave me osteoporosis, but I've graduated to osteopenia with Prolia. It is what it is. It's the one thing I can do to prevent recurrence, so I'm doing it. Good luck!

DX IDC June 28, 2014, 5 cm., 1 node tested positive (fine needle biopsy); 0/20 after neoadjuvant chemo + ALND; Grade 3; ER+ PR+ HER2+ Neoadjuvant chemotherapy starting 7/23/14 ACX 4, Taxol X 12, Perjeta X 4; Herceptin: one year Chemotherapy 7/22/2014 AC Targeted Therapy 9/16/2014 Perjeta (pertuzumab) Targeted Therapy 9/16/2014 Herceptin (trastuzumab) Chemotherapy 9/16/2014 Taxol (paclitaxel) Surgery 1/11/2015 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Hormonal Therapy 2/24/2015 Aromasin (exemestane), Zoladex (goserelin) Radiation Therapy 3/8/2015 Breast, Lymph nodes
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Feb 22, 2021 09:47PM Jstarling wrote:

Iamloved, I’ve been on Anastrazole for several years, at first I noticed leg pain and hot flashes,but it resolved itself and I’m glad I stuck it out. Just had my three year mammogram: all is well.

Dx 1/2018, DCIS/ILC, Left, 1cm, Stage IB, Grade 2, 0/4 nodes, ER+/PR+, HER2+ Surgery 2/12/2018 Lumpectomy: Left; Lymph node removal Surgery 3/2/2018 Lumpectomy Targeted Therapy 3/28/2018 Herceptin (trastuzumab) Chemotherapy 3/28/2018 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy Whole-breast: Breast, Lymph nodes

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