Topic: How large does Tumor gets chemo and herceptin

Forum: HER2+ (Positive) Breast Cancer — Testing, treatment, side effects, and more.

Posted on: Jan 21, 2012 02:05PM

Posted on: Jan 21, 2012 02:05PM

ccjj wrote:

Curious... my step mom had BMX due to high grade DCIS in left and suspicious area of concern in right.  After surgery, pathology came back with invasive ILC Her2+ in right breast. Very small, less than 1/2 cm. Sentinel nodes were clear.  Surgeon thought no chemo would be needed.  I thought all Her2+ invasive tumors were treated with chemo and herceptin.  What size warrants chemo and herceptin?

Dx 7/7/2011, ILC, 2cm, Stage IIA, Grade 2, 1/9 nodes, ER+/PR+, HER2+
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Jan 21, 2012 07:32PM racy wrote:

Bumping for you as I'm sure someone can answer this.

Dx 2010, ILC, 2cm, Stage IIA, Grade 3, 0/22 nodes, ER+/PR+, HER2-
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Jan 21, 2012 08:08PM - edited Jan 21, 2012 08:10PM by voraciousreader

According to the 2011 NCCN breast cancer treatment guidelines tumors smaller than 0.5 cm does not require Herceptin and chemo. HOWEVER, some women have said that some women with smaller tumors Than that ARE receiving Herceptin and chemo and believe the guidelines will be updated. By all means get a second opinion or ask that her case be presented to a tumor board. Good luck!

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 21, 2012 08:25PM rozem wrote:

i know a case of 3mm - chemo no herceptin and had a local reccurance 1 year later

i would get a 2nd opinion on getting the herceptin

FEC-DH, LUMP, 25 RADS, TAMOX, BMSX with LD flap (worst surgery ever) Dx 8/2011, IDC, 2cm, Stage IIA, Grade 3, 0/2 nodes, ER+/PR+, HER2-
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Jan 21, 2012 08:34PM turtle108 wrote:

I would want Herceptin at the least-

good luck with whatever you decide!

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Jan 21, 2012 08:36PM fluffqueen01 wrote:

All three oncs I interviewed said they recommend herceptin with virtually anyone that is her2+, and unfortunately, at this point most want to include chemo because they think it makes the herceptin work better.

BMX 2/10 w/TE Taxol 12 wkly/herceptin- 1 yr/ Tamoxifen now. TE’s fail/TE’s back in.  Implants 11/11- perky!" tatoo touchup remains. Be kind, for everyone you meet is fighting a hard battle. Plato Targeted Therapy 3/12/2011 Herceptin (trastuzumab)
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Jan 21, 2012 10:38PM suzieq60 wrote:

I know of cases smaller than 5mm where they ended up with distant mets less than a year later, so it's a tough decision to make.

2nd diagnosis October 2010 - IDC 5.8mm node negative - missed on mammogram in October 2009 Dx 10/13/2009, ILC, 1cm, Stage I, Grade 3, 0/5 nodes, ER+/PR+, HER2+
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Jan 22, 2012 03:39AM ma111 wrote:

A second opinion is in order here.

Dx 8/4/2009, IBC, <1cm, Stage IV, 19/19 nodes, ER-/PR-, HER2+
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Jan 22, 2012 04:42AM cbm wrote:

I would seek an medical oncology consult. Her2 changes everything and you can't be too careful in considering all the possibilities.

Cathy

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Jan 22, 2012 04:48AM momof3boys wrote:

I think she should be getting an opinion about chemo from a MO, not a BS. Perhaps that's why there is confusion?

BMX w TE reconstruction 11/11/11, 4 TC, 3/12, 25 Rads 5/12 Tamoxifin 6/12, Prophalactic hysterectomy 12/18/12, Oncotype 16 Dx 10/14/2011, ILC, 4cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2-
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Jan 22, 2012 05:54AM sassa wrote:

Definitely see a medical oncologist.  Although my cancer was an IDC, not ILC, both my surgeon and primary care doc looked at the pathology reports and said, "Congratulations! No chemo for you."

The oncologist looked at the report and said "4AC and one year herceptin."

ILC is trickier than IDC to find and diagnose. You need that second opinion.

Dx 11/6/2006, IDC, 1cm, Stage IA, Grade 3, 0/9 nodes, ER-/PR-, HER2+

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