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Topic: < 5 mm HER2+ IDC...why NOT chemo???

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jan 27, 2012 09:57AM

dancetrancer wrote:

I've read thread after thread and all of the info, opinions are running together in my head.  I've only had since yesterday to absorb all of this (was up til 1 a.m reading).  I know this is a controversial topic, but I want to hear why you WOULDN'T recommend chemo for < 5 mm of IDC her2+ (mine is 3 mm).

I had my tests run at Emory (I was there for a 3rd opinion on radiation).  They found the IDC (3 other facilities missed it, including UAB) and tested it for Her2.  Transferred my results to UAB.  Found out I was HER2+ yesterday.

UAB told me yesterday afternoon, lets cancel your radiation, meet with onc to discuss chemo next week.  Go ahead and rip your rads stickers off.  So I did.

Today they call me and say, nope, we talked to the onc and they said chemo isn't warranted with your small cancer.  Come back in to get the marks drawn back on, b/c we want to start rads ASAP next week, you are already behind schedule.

So, I've got a call into Emory to see what their onc says.  WTF.  I'm so sick and tired of sleepless nights, changing opinions, thinking I'm going to die if I don't do chemo (OK, I know that's overreacting, but you all know how it goes) and convincing myself to do it, then I hear, nope, you don't need it.  I could do without this emotional rollercoaster, thank you very much.  Now I'm afraid to NOT have chemo and am paranoid about recurrence.

HELP talk me down off the ledge please!  (LOL, just kidding, but d*mn!) 

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 17, 2012 08:36AM TheLadyGrey wrote:

Dancetrancer -- I had terrible indigestion and heartburn. My oncologist put me on Protonix -- up to 2 twice a day as needed.

Magic. It also took care of the nausea I got from the reflux so I never took another Zofran. I had the anti - nausea patch though -- you might look into that. It worked great for me.

I still take Potonix occasionally -- I've had this problem on and off for many years and had no idea there was such an effective treatment.

Surgery 10/9/2011 Mastectomy: Left; Reconstruction (left) Dx 11/1/2011, IDC, <1cm, Stage IB, Grade 3, 0/1 nodes, ER-/PR-, HER2+ Targeted Therapy 11/11/2011 Herceptin (trastuzumab) Chemotherapy 11/18/2011 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy 2/29/2012
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Apr 17, 2012 12:19PM suzieq60 wrote:

LadyGrey - hope you are doing well - good to hear from you

Sue

2nd diagnosis October 2010 - IDC 5.8mm node negative - missed on mammogram in October 2009 Dx 10/13/2009, ILC, 1cm, Stage I, Grade 3, 0/5 nodes, ER+/PR+, HER2+
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Apr 17, 2012 04:59PM chachamom wrote:

Hello...I'm supposed to be elated but I'm confused....the oncologist says "no need" for chemo, nor Herceptin, even with the HER2 + status....that "statistically" there's no benefit to the chemo/Herceptin because of the small size of the cancer (.3 cm).....he's recommending Arimadex hormone therapy only. My DH is happy....and can't understand why I'm not too.....I SHOULD be , right?
I am asking for a second opinion......and he's ordered a CA-27-29 test only because my BS did that test pre-surgery and it was elevated. He says that test is not usually ordered nor should it have been, because it's "unreliable" and leads to unnecessary follow-up CT scans etc..."Pandora's Box"
Am I worried uneccesarily? Jill

Jill. Age 59. "Life is a shipwreck, but we must not forget to sing in the lifeboats." - Voltaire. No chemo/herceptin and no radiation because the largest of multi focal tumors was 3mm Dx 3/12/2012, IDC, <1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2+ Hormonal Therapy 5/30/2012
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Apr 17, 2012 06:40PM fluffqueen01 wrote:

I would get a second and third opinion and then make your decision after you weigh all the info. I think dancetrancer and maybe lady grey had similar sizes.

BMX 2/10 w/TE Taxol 12 wkly/herceptin- 1 yr/ Tamoxifen now. TE’s fail/TE’s back in.  Implants 11/11- perky!" tatoo touchup remains. Be kind, for everyone you meet is fighting a hard battle. Plato Targeted Therapy 3/13/2011 Herceptin (trastuzumab)
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Apr 17, 2012 06:52PM dancetrancer wrote:

Jill, I'm sorry, this is exactly the dilemma I faced as well.  First onc said no chemo, didn't feel the recurrence risk was high enough and didn't trust the retrospective studies from MD Anderson.  2nd onc said yes, definitely need chemo.  Third onc said he would treat me if it gave me more peace of mind, as the biology of the tumor (HER2+) does play a role.  I finally went to MD Anderson, and they did feel my risk was higher b/c of the HER2+ combined with being  younger; they strongly recommended chemo/Herceptin.   They feel biology of the tumor definitely trumps the size.  Of course this is all based on their own research.  I chose to put much stock into their recommendation b/c I feel they have done the most research on tiny HER2+ tumors.   This is all so very controversial, and it makes it incredibly difficult to make a decision as a patient.  I finally decided I didn't want any regrets ie. finding out a year or two from now that I had metastatic cancer that could not be cured.  I agreed to at least try chemo...with the mindset that if it was just too difficult or I encountered any really bad side effects I would stop and then continue the Herceptin only for the year (Herceptin has risks, for sure, but is much better tolerated than the chemo, and it targets the HER2+ receptor).  

I hope this helps, I totally understand and feel your pain.  You may want to read back through this long thread and read all of the research info presented/debated and the thought process I went through.   

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 17, 2012 10:20PM chachamom wrote:

Thanks, Dance and Fluffqueen.......I just feel numb right now....my DH and mom are happy....and I feel guilty for feeling doubt....I asked my Onc specifically if my age was a factor.....and if my multifocal status had any bearing...he said " no".......but I'm wondering if age might be an issue. I feel weird about making too much over what he says is " less than" a 10% statistic of recurrence. I have to mull this one over....but I'll wait for my second (and maybe 3rd) opinion before I do the Happy Dance.

Jill. Age 59. "Life is a shipwreck, but we must not forget to sing in the lifeboats." - Voltaire. No chemo/herceptin and no radiation because the largest of multi focal tumors was 3mm Dx 3/12/2012, IDC, <1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2+ Hormonal Therapy 5/30/2012
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Apr 17, 2012 10:22PM chachamom wrote:

..and I WILL reread this thread from the beginning, thanks!

Jill. Age 59. "Life is a shipwreck, but we must not forget to sing in the lifeboats." - Voltaire. No chemo/herceptin and no radiation because the largest of multi focal tumors was 3mm Dx 3/12/2012, IDC, <1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2+ Hormonal Therapy 5/30/2012
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Apr 19, 2012 05:44AM dancetrancer wrote:

vjm - you are now 6 days post your chemo - wondering how you are holding up?  I know days 3 to 6 were the worst for me.  Hoping to hear from you! 
Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 19, 2012 11:22AM vjm wrote:

Hey Dancetrancer - thanks for checking in. It's not horrible with a capital H, but I definitely am treading lightly. Most difficult thing is radiation burn agravated by chemo - 2nd degree and lots of pain like branding iron being inserted!!! Tramacet helps a bit, but now constipated with a pretty touchy stomach. My husband says I'm not the same on narcotics....REALLY!!!! Maybe because my breast is disintegrating onto my nightie, I'm bunged up to the eyebrows, I had chemo on Friday and my breast could power New York City for a year!!!! Sorry I am a wee bit emotional and sensitive sweetheart!!!

Here's looking at you kid - clink with the prune juice in a champagne glass! Lots of love - let me know how u doin'? vjm

ps 10k training on hold.

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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Apr 19, 2012 03:26PM dancetrancer wrote:

Oh no about the radiation burn vjm!  I bet it is worse for you b/c you were so soon after rads.  I think I ended up having to wait 2 or 3 weeks by the time I had my port, recovery from lung collapse, etc.   LOL on the narcotics...for REAL!!!!  OMG, I am so the same way!  You are cracking me up!  You be as emotional and sensitive as you wanna be...we deserve the right to be that way after all we have been through!  

Cha-chink!!!  Hey - ask your onc about probiotics...I started them yesterday...no major movement yet, but moving...I think it is helping!!!  One has to be so careful not to push over to the other side too far  - the Big D train...that's what happened with me...big C, then big D, now small C...ba-ha-ha.  Someone please let me off the d*mn train!   

Uh yeah...that 10K training likely won't be happening for a bit!

I'm doing much better since day 8 post chemo (Tuesday).  However, I am facing serious Grade IV neutropenia.  I did not get Neupogen preventatively.  So, I started it today, along with Cipro to help prevent serious infection.  Scary stuff!!! But I feel fine.  How crazy is that?   

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 19, 2012 10:33PM fluffqueen01 wrote:

Ducolax stool softener....lifesaver. Just saying.

BMX 2/10 w/TE Taxol 12 wkly/herceptin- 1 yr/ Tamoxifen now. TE’s fail/TE’s back in.  Implants 11/11- perky!" tatoo touchup remains. Be kind, for everyone you meet is fighting a hard battle. Plato Targeted Therapy 3/13/2011 Herceptin (trastuzumab)
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Apr 20, 2012 04:57AM dancetrancer wrote:

Thanks fluff.  My onc only wants me to use Miralax, seems to think it is gentler.  Who knows.  And since I am now on Cipro, which can cause diarrhea...he's wary of me taking much of anything else to make things move...we'll see...if I don't get off the C train soon, Miralax will be on my order ticket!!! 

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 20, 2012 05:45AM lago wrote:

I never liked Ducolax. It harsh for me even when I wasn't on chemo. I took Metamucil 3X a day as directed when I had the big C. Worked well for  me. I think Miralax is in the same family.

DONE!! goo.gl/IoaN6U • Tattoos 2.7.2012 • Nipples 10.6.2011 • Exchange 6.24.2011 • Chemo 1.18. 2011 • BMX 8.31.2010 Dx 7/13/2010, IDC, 5cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2+
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Apr 20, 2012 06:06AM dancetrancer wrote:

Thanks Lago.  I took a 1/2 dose of Miralax (I'm so cautious about the Big D!) a day or two ago with no significant results.  You got me curious (what else is new).  I don't believe they are in the same family, despite the name.  

Miralax is listed as a hyperosmotic agent.    It works by causing water to be retained with the stool. This increases the number of bowel movements and softens the stool so it is easier to pass.

Dulcolax is listed as a stimulant laxative.   It works by increasing activity of the intestines to cause a bowel movement.  According to additional reading I found that they are the most severe among laxatives and should be used with care.

So although the names sound similar, they are quite different.  Who knew???  

BTW, I'm off the C train.  Probiotics and my green tea (and maybe a kick from the Cipro?) seems to have done the trick.  TMI!!  

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 20, 2012 06:12AM lago wrote:

No I think Miralax is in the same family as Metamucil

DONE!! goo.gl/IoaN6U • Tattoos 2.7.2012 • Nipples 10.6.2011 • Exchange 6.24.2011 • Chemo 1.18. 2011 • BMX 8.31.2010 Dx 7/13/2010, IDC, 5cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2+
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Apr 20, 2012 09:45AM dancetrancer wrote:

Oh, oh, oh Lago - I totally misread your comment!  I thought you were saying Miralax was in the same family as Dulcolax!  LOL!!!  Oh well, I educated myself a little more in the process. Tongue out
Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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Apr 20, 2012 06:03PM fluffqueen01 wrote:

Miralax is good too. I do not use the dulcolax laxative. It is just a stool softener.My problem with Miralax is that I don't like the powered stuff in my drink. I am convinced I can taste It!

I also use probiotics, which help a ton.

BMX 2/10 w/TE Taxol 12 wkly/herceptin- 1 yr/ Tamoxifen now. TE’s fail/TE’s back in.  Implants 11/11- perky!" tatoo touchup remains. Be kind, for everyone you meet is fighting a hard battle. Plato Targeted Therapy 3/13/2011 Herceptin (trastuzumab)
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Apr 26, 2012 11:45AM vjm wrote:

How are you doing Dancetrancer? Celebrating today the return of normal GI tract!!! Nose a little runny and hair starting to shed a little more tho. Acupuncture for neuropathy. I used Nebussa s.c. two days post-chemo to prevent neutropenia. Not part of standard protocol here in Victoria, but my onc is using it now prophylactically. I plan to repeat for my next 3 sessions. Back on track for 10k race this Sunday (planning to walk it now tho as the thought of my burned breast bouncing on sports bra is too much to bareSmile). Enjoy this day and let me know how you is. v.
Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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Apr 26, 2012 12:16PM dancetrancer wrote:

Yay vjm!!!  Great to hear from you!  I'm doing pretty well now, much better than the first two weeks!  I developed a runny nose - got some great suggestions from gals on the TCH thread - vaporizer, saline nasal spray, placing a small amount of vaseline/other moisturizer in the nose.  I started with a bit of baby oil on a Q-tip yesterday a couple times a day, and it seems to be keeping the majority of the sniffles away so far.

You already have signs of neuropathy with one treatment?  I'm doing some supplements to try to keep it at bay.  So far...so good...knock on wood.  It's one of my biggest worries!   I have a call into a local acupuncturist.  I'm thinking it may be worth a try to see if it helps keep my sx managed better next time.  Hope he calls me back soon - excited about trying it!   

What's nebussa?  They put me on Neupogen for 4 days - brought my white counts right up.  I'll be getting it a bit earlier next time to try to prevent them from dropping so far.  You go on the 10K - even walking it is WAY impressive to me.  WOW!  You are doing GREAT!!!   

No significant hair shedding for me yet.  As you know, I used the cold caps for my head, but I'm watching the rest of my body.  Just a tiny bit of extra shedding noted so far.  I think the onslaught is about to start though!   

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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May 2, 2012 04:45PM vjm wrote:

Hey Dancetrancer - how are you post 2nd chemo? Thinking of you lots. Finished the 10k - it wasn't fast, it wasn't pretty, but we go 'er done:) Exhausted after - but worth every minute for me. Since then I have had a formal head-shaving party on the rocky bluffs with a rainbow in the east, sun overhead, and a wicked rain storm blowing in from the west with a bottle of wine and espresso vodka, my dtr and four of my bestest friends! Now I am sporting an itchy warm wig that pretty much looks like my old hair. 2nd chemo on Friday and I am feeling strong and ready. Keep in touch and let me know how you are doing:) v.

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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May 2, 2012 05:23PM dancetrancer wrote:

Huge congrats vjm on finishing the 10K - wow!!!  

Your head shaving party sounds magical!!!  What a great idea!

I'm doing pretty well - just day 1 post 2nd TCH, so it is tough to tell - still on the steroid high.  I did have the D train this morning, but that train has temporarily stopped.  Fever (low grade) has started already.  But energy level still good while on the steroids, so still plugging along.  Tomorrow...well...we'll see and deal!

Best wishes for your 2nd one Friday!!!  

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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May 7, 2012 11:38AM vjm wrote:

Good Morning Dancetrancer - how goes the journey? Busy rinsing mouth with baking soda and trying to ease my aching knees.... second chemo a little rougher. Feeling more emotional and achy this time. Going to curl up with it a bit and enjoy some of the many books awaiting me. Let me know how you are doing and know that I am thinking of you. xo V.

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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May 7, 2012 12:02PM dancetrancer wrote:

Hey vjm, I was just thinking of posting here to ask YOU how YOU are doing!  I guess you are now day 3 post...hang in there sweetie...I know the ride can be pretty rough...but it will end.  Just not soon enough, LOL!   I wonder what is causing the aching knees?   I hadn't heard of that as a side effect of TCH.  Maybe it's the Herceptin?   Or are you getting neupogen/neulasta?  If so, that can cause bone pain, but taking Claritin can prevent the bone pain from being really bad.  

I am now day 6 post my 2nd TCH.  This 2nd round has been better for me so far - less severe diarrhea/constipation fluctuations.  I really think that probiotic plus drinking prune juice/having prunes on my oatmeal daily is a big help.  I've got thrush AGAIN, lovely.  Doing the old magic mouthwash to keep it under control as best I can.   I started a low-grade fever again as of yesterday; my counts are into "moderate" (Grade III) neutropenia today.  Onc still wants to hold off on Neupogen.  I assume he does not like to give it unless the counts go into Grade IV.  I suspect I'll be there by tomorrow, since nadir for TCH is days 7 to 10.  We'll see! 

I've switched to Herceptin at the lower weekly dose, so I go in for my weekly Herceptin tomorrow.

My worst symptom this round has been again, severe indigestion.  It presents as uncomfortable burping, burning/tightness/pain in my chest (yeah, doc knows...doesn't seem to think it is heart related...make sense...I feel relief when I burp), and nausea.    This is despite taking the max allowable of every med given to me - Zofran, Protonix, magic mouthwash (has Maalox in it), Pepcid, and even a few TUMS when I was desperate and not due for any other med.   I talked to them today, and they are going to double up my Protonix.  Crazy.  I'm not surprised, though, since I had severe reflux PRIOR to chemo.  At one point I had to be on double Nexium and Reglan to stop breakthrough symptoms.   So I am quite hopeful the double Protonix will help.  Hate to do it, but the symptoms just aren't manageable, and I need some relief.  This chemo/dex is doing a number on my GI system, for sure.  I hope I'm not doing any permanent damage to my esophagus!  

Ah well, guess I sound like a complainer.  Can't help it...in the mood to vent!   I feel a little better now just getting it out. Laughing  I totally understand the being more emotional.  This stuff takes its toll on ya. 

I may curl up with a movie this afternoon. Let's try to enjoy our couch time!!! Smile  Thinking of you!! 

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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May 8, 2012 05:25AM lago wrote:

Just saw this on the Herceptin site:

Herceptin is approved for the treatment of early-stage breast cancer that is Human Epidermal growth factor Receptor 2-positive (HER2+) and has spread into the lymph nodes, or is HER2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (ER/PR)-negative or have one high risk feature.* Herceptin can be used in several different ways: 

*High risk is defined as ER/PR-positive with one of the following features: tumor size >2 cm, age <35 years, or tumor grade 2 or 3.

Source: near the end of the page www.herceptin.com/breast/herce...

But this information might be dated and as we know things change all the time. Herceptin is still new.

DONE!! goo.gl/IoaN6U • Tattoos 2.7.2012 • Nipples 10.6.2011 • Exchange 6.24.2011 • Chemo 1.18. 2011 • BMX 8.31.2010 Dx 7/13/2010, IDC, 5cm, Stage IIB, Grade 3, 0/14 nodes, ER+/PR+, HER2+
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May 8, 2012 05:49AM dancetrancer wrote:

Yep, lago, saw that.  Grade 2 is the only thing that qualifies me.  I'm definitely on the low end of the scale of risk when it comes to HER2+, but according to MD Anderson, the risk is still high enough to recommend TCH for me.  They estimated my total recurrence risk without TCH ~ 20 - 25%.  Of course this is vastly different from the first oncologist I met with, who said no chemo/Herceptin for me, and estimated my recurrence risk I think around 5 or 10% (memory is starting to go!).

No easy answers for tiny HER2+ patients; ends up being a gut call and what kind of risk you think you can live with, or not.  

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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May 14, 2012 12:56PM vjm wrote:

Hi Dancetrancer - surfacing from that first week post-chemo.... wow wicked! Curious about Claritin from my severe bone pain. Claritin? Really? Yes, it was from neulasta that I take each time and despite many balms, narcotics, and soaking it really was the worst part this time! I did manage to get out for a glorious mother's day and enjoy some time with my family. Now, wanting to get strong again so I don't disrupt my schedule for the last two chemo tx's.... halfway now! How are you doing? Sounds like reflux is awful for you. I too have a hx of GERD and take Pantoloc. Adding more TUMS with the GI stuff as well. I'm reading a great collection of  writings called Living on the Margins - Women Writers on Breast Cancer, edited by Hilda Raz. Some great insight, experiences, poems, and shared wisdom. I too would rather be in Italy with Chachamom!!! Ciao and cheers to you! V. xo

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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May 18, 2012 09:23AM dancetrancer wrote:

vjm, somehow I missed your reply...SORRY!  Yes, Claritin!  It's awesome!  It helps decrease the inflammation associated with the Neupogen/Neulasta shot...and hence the pain.  I have taken it with my Neupogen and have had virtually NO PAIN.   If you take Neulasta, the clinical trial says to take 10 mg loratadine (or Claritin) the day of and 7 days post (b/c Neulasta is long acting).  With neupogen, I just take it every time I get a shot (at least 30 minutes before-hand). 

My reflux finally has calmed down with multiple meds (YAY!), plus I had an endoscopy this morning to make sure there was no severe damage - none - YAY.  So I am on schedule for my next TCH this coming Tuesday.  Oh, and I have decided I'm only going to do 4 as well.  6 just seems like overkill for our size tumor.  So I'm half way, too.  YAY!!!!!!!!!!

I'm going somewhere REALLY fun when this is all over...DH and I are talking about a cruise.  I don't care where, as long as I am far, far away from treatment!  LOL!!!!   We are getting there! 

Cold caps work! coldcapphotos.shutterfly.com/p... TCH: 4/10 - 6/13/12; 33 rads; BMX w/fat grafting; DX: 7/29/11 @ age 43: Stage 1A on L (3 mm IDC w/ 6 cm DCIS, Gr 2 ER/PR+, HER2+) 0/3 nodes; Stage 0 on R (2 mm DCIS); see bio.
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May 18, 2012 12:53PM vjm wrote:

Dancetrancer - congratulations with your decision to do 4. I am completely at peace with 4 for myself as well. I will try the claritin. My burned to rat shit breast is almost healed too! We are also planning a nice holiday to some music festivals on Vancouver Island and then in to the interior to Penticton to see our favourite blues musician Matt Anderson.... a light at the end of this tunnel:) Tired tho and hoping Chi Gong this afternoon will help restore some energy for my anniversary trip tomorrow to Salt Spring Island for the market and a lunch in a cozy cafe. Take care Dance and all the best on Tuesday. My 3rd is next Friday. vjm xoxo

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy
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May 18, 2012 10:27PM fluffqueen01 wrote:

Wow, Lago, with that info, grade 2 would be the only thing that qualified me also. That is ineresting.

Dance...glad you reminded me about the claritin. I never had the neulasta shots as I didn't need them. The onc says Taxol isn't as bad for that. But, now that I am doing that study, Leukine is part of it, either as the placebo or the vaccine with the leukine.

I have noticed my hip joints were really achy. I am going to use the Claritin next time.

BMX 2/10 w/TE Taxol 12 wkly/herceptin- 1 yr/ Tamoxifen now. TE’s fail/TE’s back in.  Implants 11/11- perky!" tatoo touchup remains. Be kind, for everyone you meet is fighting a hard battle. Plato Targeted Therapy 3/13/2011 Herceptin (trastuzumab)
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May 21, 2012 01:27PM vjm wrote:

Kick chemo ass tomorrow Dancetrancer!

Enjoy this day - get that laxative goingUndecided

vjm

Dx 10/28/2011, IDC, <1cm, Stage IA, Grade 3, 0/2 nodes, ER+/PR+, HER2+ Surgery 11/29/2011 Lumpectomy: Right Surgery 12/28/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 3/12/2012 Breast Targeted Therapy 4/13/2012 Herceptin (trastuzumab) Chemotherapy 4/13/2012 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy

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