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Topic: Anyone on Taxotere, Perjeta and Herceptin

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Mar 3, 2014 09:37AM

waterdog wrote:

I am about to start this series on March 13.  Any input on what to expect or your successes would be great!

11/14/2013, IDC, Grade 2 Dx 11/14/2013, IDC, 2cm, Grade 3, 1/4 nodes, ER+/PR-, HER2+ Chemotherapy 12/19/2013 AC Targeted Therapy 3/13/2014 Perjeta (pertuzumab) Targeted Therapy 3/13/2014 Herceptin (trastuzumab) Chemotherapy 3/13/2014 Taxotere (docetaxel) Surgery 6/18/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Hormonal Therapy Femara (letrozole) Radiation Therapy Breast
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Mar 3, 2014 11:53AM CancerVixen wrote:

I just started taxotere, perjeta, herceptin and carobplatin this past Wednesday. 

Dx 12/20/2006, IDC, 2cm, Stage II, Grade 1, 0/3 nodes, ER+/PR+, HER2- Dx 1/27/2014, IDC, 1cm, Stage IIIA, Grade 3, ER+/PR+, HER2+ Chemotherapy 2/25/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Mar 3, 2014 12:55PM Mmm2014 wrote:

I just started this regimen also and would like to know how others are doing with this?  My first tx was 2/13/14. My next tx is 3/6/14 and not looking forward to it. I had to go gluten free after the first tx. My tummy was a mess but anytime I get stressed it goes straight to my tummy. 

Dx 1/2014, IDC, Stage II, Grade 2, ER+/PR-, HER2+ Targeted Therapy 2/13/2014 Herceptin (trastuzumab) Targeted Therapy 2/13/2014 Perjeta (pertuzumab) Chemotherapy 2/13/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Mar 3, 2014 02:24PM - edited Mar 3, 2014 02:38PM by ben50

My wife is 26 and on TCHP (Taxotere, Carboplatin, Herceptin, & Perjeta) 5/6. Her side effects have actually been well tolerable (relatively speaking). Hardly any nausea, in fact her appetite has been spectacular and unchanged since chemo began. She takes prescribed steroids before chemo infusions to help with this and it appears to have worked well. Her hair fell out a little after her second round of chemo (probably about 4 weeks after treatment began). She still has her eyebrows (thinned out a little but definitely still there) and her eye lashes look unchanged. The first week after any given infusion is the most difficult. During that first week she is generally more tired and has less energy to do things. She is rarely in pain though. Furthermore, she has worked full-time during this whole process and is fine, although she can be quite tired the first week back (understandably). Most likely her worst side effect has been stomach/gastrointestinal issues, such as diarrhea and constipation - which has always seemed to be her friend throughout chemo, unfortunately.

But honestly, it hasn't been terrible (mind you this is coming from her observing and helping husband, though I believe she would agree with me for the most part). The very best part of neoadjuvant chemo has to be that her 2.7 lump (very tangible at first) totally melted within 1-2 weeks. By the second infusion, it had disappeared completely. This cocktail works amazing for Her2+ ladies and Perjeta is cutting edge. Please keep in mind, however, this was our experience and your's could be different as all our bodies are different and react to things differently.

If you have any other questions in regards to what to expect, feel free to ask! When you're married to someone with breast cancer, it almost feels like you have it yourself. Not to mention I'm the zealous researcher in the family (she's happy to know enough to make informed choices - which works great for her).

Dx 11/7/2013, IDC, 2cm, Stage II, Grade 3, 1/6 nodes, ER+/PR+, HER2+
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Mar 3, 2014 05:49PM NinaW wrote:

I have nothing whatsoever to add, as I won't be starting chemo for another week or so and am pretty sure I won't be able to sweet-talk an onco into giving me Perjeta because my tumor falls in the gap between approved protocols, but I just wanted to let Ben know how lovely I think it is that he's on here and doing so much research for his wife. It's really true that an illness like cancer is very much a "family" disease.  Your wife is very lucky to have you on her team! Hope you're taking good care of yourself as well.

'Adjudge my strength, and set me where I bear a little more than I can bear' - Elinor Wylie Sonnet XVI Dx 1/24/2014, IDC, 1cm, Stage I, Grade 2, 0/1 nodes, ER+/PR-, HER2+ Surgery 2/10/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Targeted Therapy 3/12/2014 Herceptin (trastuzumab) Chemotherapy 3/12/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Mar 4, 2014 11:04AM - edited Mar 4, 2014 11:07AM by jhsped

I'm on TCH and Perjeta too.  I have completed 4/6 infusions so far.

Dx 12/9/2013, IDC, Right, Stage IIIA, Grade 3, ER+/PR+, HER2+
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Mar 5, 2014 08:33AM Mmm2014 wrote:

Hi jhsped, how are the treatments going for you. I go for my second tomorrow. I'm nervous. The SE we're not enjoyable. Hopefully I have a better handle on them now. Has your tumor shrunk at all. I believe mine has but I'm not a doc. Please keep us posted. Hard to find other women on the tx plan as us. God bless!

Dx 1/2014, IDC, Stage II, Grade 2, ER+/PR-, HER2+ Targeted Therapy 2/13/2014 Herceptin (trastuzumab) Targeted Therapy 2/13/2014 Perjeta (pertuzumab) Chemotherapy 2/13/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Mar 7, 2014 04:41PM CancerVixen wrote:

Its been 9 days since my first treatment and although I am still suffering through severe abdominal pains I am so happy to say I cant even feel my tumor anymore!  I cant believe it has shrunk so much from one treatment. My energy is finally coming back.  Not looking forward to the next 5 treatments though!

Dx 12/20/2006, IDC, 2cm, Stage II, Grade 1, 0/3 nodes, ER+/PR+, HER2- Dx 1/27/2014, IDC, 1cm, Stage IIIA, Grade 3, ER+/PR+, HER2+ Chemotherapy 2/25/2014 Carboplatin (Paraplatin), Taxotere (docetaxel)
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Mar 14, 2014 03:22PM flantille wrote:

I completed this exact regimen about 6 weeks ago and just got the pathology report back from my surgery--pathologic complete response!! I highly recommend the regimen and hope you have success with it. Be sure to get the neulasta shot, though, because my blood counts went to zero without it. Once I had the shot, though, I really didn't have too much trouble with this regimen--some bone aches the first few days, feeling a little tired and out of it the third and fourth day, almost total hair loss, and very dry skin including in my nose. But no nausea and I usually felt pretty good by the end of week 2. :)

Dx 10/18/2013, IDC, 6cm+, Stage IIIA, Grade 3, 5/15 nodes, ER-/PR-, HER2+ Targeted Therapy 11/19/2013 Perjeta (pertuzumab) Targeted Therapy 11/19/2013 Herceptin (trastuzumab) Chemotherapy 11/19/2013 Taxotere (docetaxel) Surgery 2/18/2014 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left; Reconstruction (left): Tissue expander placement Chemotherapy 3/18/2014 CEF
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Mar 17, 2014 07:06AM - edited Mar 17, 2014 07:07AM by waterdog

Thanks for responding.  I did the THP on Thursday without neulasta (not sure why I asked not to have neulasta but I did) and I am definitely feeling under the weather today.  Feeling run down.  I have already had four rounds of a/c without much SE and only mild nausea.  My 2.7 cm tumor shrunk to about 30 percent of what it was on the a/c so I'm hoping this next series knocks the tumor out!  Looking forward to feeling "normal" and planning my new hair style.  Three treatments left.  Yay!

11/14/2013, IDC, Grade 2 Dx 11/14/2013, IDC, 2cm, Grade 3, 1/4 nodes, ER+/PR-, HER2+ Chemotherapy 12/19/2013 AC Targeted Therapy 3/13/2014 Perjeta (pertuzumab) Targeted Therapy 3/13/2014 Herceptin (trastuzumab) Chemotherapy 3/13/2014 Taxotere (docetaxel) Surgery 6/18/2014 Lumpectomy: Left; Lymph node removal: Left, Sentinel Hormonal Therapy Femara (letrozole) Radiation Therapy Breast
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Mar 17, 2014 01:58PM Anneb1149 wrote:

I had four rounds of this treatment between Oct and Dec 2013. I had a rough time. I lost all my hair and suffered with nausea,achiness and fatigue. I also had bad diarreah and no appetite. Nothing tasted right, not even water. It would start about 48 hrs after treatment and last for up to two weeks. All that said, though, it did it's job and the cancer was gone by the end of the treatments, so to me it was worth it. I am in my mid 60's and I live with my oldest daughter and her family. She and her husband did everything they could to make me as comfortable as possible. Since chemo, I have had a double mastectomy and am waiting for a start date on radiation. All the side effects of the chemo have worn off and I am pretty much back to normal activities. I hope this doesn't scare you- everyone reacts differently, and my point really is that no matter how bad your reaction might be, it is for a limited period of time, and it does what it is supposed to do. Stay strong, and focus on the day they tell you that you are cancer free.

Dx 9/25/2013, IDC, 1cm, Stage IIIA, Grade 2, 3/9 nodes, ER-/PR-, HER2+ Targeted Therapy 10/4/2013 Herceptin (trastuzumab) Targeted Therapy 10/4/2013 Perjeta (pertuzumab) Chemotherapy 10/10/2013 Taxotere (docetaxel) Surgery 1/28/2014 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Left, Right Radiation Therapy Breast, Lymph nodes
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Mar 27, 2014 11:55AM Lovemysons wrote:

I just had my first treatment of taxotere, herceptin and perjeta on Tuesday.  Had the neulasta shot yesterday and I'm thankful to say I'm feeling pretty well.  I'm praying this continues!!  Five more to go, then surgery and radiation to follow.  Glad for all the testing to be finished and to finally get started on getting rid of it!!

Dx 2/19/2014, IDC, 4cm, Stage IIB, Grade 3, 0/7 nodes, ER+/PR+, HER2+ Targeted Therapy 3/24/2014 Herceptin (trastuzumab) Targeted Therapy 3/24/2014 Perjeta (pertuzumab) Chemotherapy 3/24/2014 Taxotere (docetaxel) Chemotherapy 5/6/2014 Carboplatin (Paraplatin) Surgery 9/9/2014 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap, Tissue expander placement; Reconstruction (right): DIEP flap, Tissue expander placement
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Mar 28, 2014 01:46PM - edited Mar 28, 2014 01:47PM by ben50

You'll do great, Lovemysons. You're getting cutting edge treatment and I think you'll enjoy feeling your tumor melt to death (if it was ever palpable to begin with). 

So, one interesting side effect from the taxotere that kind of declared itself here at the end of the game is my wife's fingernails. She has developed what I can only describe as tree ring-like lines on her nails (like a line for every chemo infusion). They also seem to be growing out sideways and getting a little yellowish in color. They can hurt a bit and she has trouble opening things up like cat food, but it's not too troublesome for her. Taxotere's website listing for SE's pretty much described what was happening perfectly and our onc says it will normalize itself in a few months. Anyways, it was an interesting new develop and thought I'd share.

Dx 11/7/2013, IDC, 2cm, Stage II, Grade 3, 1/6 nodes, ER+/PR+, HER2+
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Apr 10, 2014 12:27PM carolsue63 wrote:

I go for round 5 of TCH+P tomorrow, and it's been kicking my butt. But it's been kicking the cancer's butt too, so that's okay. I'm stage 4 with lung and bone mets. Just had a PET scan last week, and it showed dramatic improvement since my diagnosis in January -- near complete resolution of the lung infiltrates, bone spots are "stable" on the CT part of the scan (MO said that was good -- apparently it's hard to get those to go away) , and on the PET part of the scan, they weren't lighting up anymore. NOTHING lit up at all!!!  Side effects from this cocktail are rough, but it's working like magic on me. I hope all of you see awesome results too! :-)

Dx 10/20/1997, DCIS, Stage 0, 0/8 nodes Surgery 11/16/1997 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 1/13/2010, IDC, 3cm, Stage IIB, 1/14 nodes, ER+/PR+, HER2+ Targeted Therapy 3/18/2010 Herceptin (trastuzumab) Chemotherapy 3/18/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 8/19/2010 Breast Dx 1/8/2014, Stage IV, ER+/PR+, HER2+ Targeted Therapy 1/14/2014 Herceptin (trastuzumab) Targeted Therapy 1/14/2014 Perjeta (pertuzumab) Chemotherapy 1/14/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)
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Apr 10, 2014 01:17PM ben50 wrote:

Truly awesome news, carolsue, be proud of yourself for sticking with it for 5 infusions. Perjeta is a game changer. And just a side thought, because you have metastatic disease, you could likely get get TDM-1 if you choose, which attacks Her2+ tumor cells in a new and dynamic way from Herceptin and Perjeta (maybe think of it as Herceptin-Advanced). Keep fighting the good fight! 

Dx 11/7/2013, IDC, 2cm, Stage II, Grade 3, 1/6 nodes, ER+/PR+, HER2+
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Apr 11, 2014 05:19PM carolsue63 wrote:

Thanks for the suggestion -- that's Kadcyla, isn't it? I've heard it mentioned but don't know much about it. I assume that will be in my MO's bag of tricks down the road.

Dx 10/20/1997, DCIS, Stage 0, 0/8 nodes Surgery 11/16/1997 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 1/13/2010, IDC, 3cm, Stage IIB, 1/14 nodes, ER+/PR+, HER2+ Targeted Therapy 3/18/2010 Herceptin (trastuzumab) Chemotherapy 3/18/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 8/19/2010 Breast Dx 1/8/2014, Stage IV, ER+/PR+, HER2+ Targeted Therapy 1/14/2014 Herceptin (trastuzumab) Targeted Therapy 1/14/2014 Perjeta (pertuzumab) Chemotherapy 1/14/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)
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Apr 30, 2014 05:44AM orpheus wrote:

My wife (de novo stage 4) just started THP, and doing OK with it so far SE-wise.

As I see some of you have Carboplatin added in to the mix, I was wondering if some here knew about the rationale for THP vs. TCHP oncologist choice. Can't find much literature on this, but I suspect there must be a prognosis/response reason for having it or not.

"You're off to Great Places! Today is your day! Your mountain is waiting, so... get on your way!" - Dr. Seuss Dx 3/2014, Stage IV, Grade 3, mets, ER-/PR-, HER2+
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Apr 30, 2014 01:17PM carolsue63 wrote:

I've been curious about that, too. I'm getting TCHP. Since I had TCH 4 years ago, I didn't think much about just adding Perjeta this time. But seeing some people get only THP has made me wonder. I go for my last round of TCHP this Friday and will ask about it if I get a chance. (I don't always get to see the doctor on chemo day.)

Dx 10/20/1997, DCIS, Stage 0, 0/8 nodes Surgery 11/16/1997 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 1/13/2010, IDC, 3cm, Stage IIB, 1/14 nodes, ER+/PR+, HER2+ Targeted Therapy 3/18/2010 Herceptin (trastuzumab) Chemotherapy 3/18/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 8/19/2010 Breast Dx 1/8/2014, Stage IV, ER+/PR+, HER2+ Targeted Therapy 1/14/2014 Herceptin (trastuzumab) Targeted Therapy 1/14/2014 Perjeta (pertuzumab) Chemotherapy 1/14/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)
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Apr 30, 2014 02:14PM Kite wrote:

I'm doing this cocktail too. Just had my first round last week. It's been rough with the SE. My first round of chemo (2012) I did TCH and now it's THP. I've looked all over the internet and I've seen nothing but good outcomes with Perjeta. I will hopefully get my scans back from how much radiation shrank my bone mets next week. Then I'll have another scan when my treatments are over. I am learning over all it's they Taxotere that sucks the life out of you. Not the perjeta. 

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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Apr 30, 2014 02:48PM Lovemysons wrote:


Had an MRI today.  I've had two cycles of THP chemo and there hasn't been any change.  I was really hoping to see some reduction.  Looks like the onc will probably be adding carboplatin to the next round.  So far I've tolerated the side effects well but what can I expect from adding this new drug?

Dx 2/19/2014, IDC, 4cm, Stage IIB, Grade 3, 0/7 nodes, ER+/PR+, HER2+ Targeted Therapy 3/24/2014 Herceptin (trastuzumab) Targeted Therapy 3/24/2014 Perjeta (pertuzumab) Chemotherapy 3/24/2014 Taxotere (docetaxel) Chemotherapy 5/6/2014 Carboplatin (Paraplatin) Surgery 9/9/2014 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): DIEP flap, Tissue expander placement; Reconstruction (right): DIEP flap, Tissue expander placement
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May 12, 2014 08:51AM Kite wrote:

I had carbo with my first diagnosis but I also had taxotere with it so I don't know how it was on its own. I know it all just makes you feel awful. I did have to reschedule some infusions because my counts were so low. My once said the carbo does that. But taxotere does too.... 

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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May 12, 2014 03:20PM srdc2013 wrote:

I did 3 treatments with TCHP and today had my 4th with just THP.  We dropped the carbo b/c I am experiencing hearing loss.  Apparently that NEVER happens with breast cancer patients.  I'm that one in a million I guess.  I was on schedule to do 6 TCHP treatments and then surgery but since we dropped the carbo I am having surgery in 2-3 weeks and then more chemo.  She doesn't even know which cocktail to use post surgery since I'm off the treatment plan now.  We'll just have to wing it.  I have many of the same SE's - the first week is dreadful.  I get sore from head to toe (warm baths in epsom salts help enormously), depression, fatigue and then the diarrhea hits.  It's 10-14 days of diarrhea due to the taxotere and perjeta but it's more manageable each cycle.  I started acupuncture after my second treatment and it's helped alot both with the diarrhea and my low red counts.  Last go around I was able to go back to work during Thursday of the second week.  It had been the third week each time before.  I had an ultrasound and mammogram last friday and my tumor was gone!  So that's good news at least!  

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May 12, 2014 05:40PM Kite wrote:

srdc-That is awesome the tumor is gone! I got some results that were good too! My pelvic tumors are gone and my spinal ones have shrunk a lot.

Sorry about the nasty SE. I'm not happy you have had to put off work but I'm relieved to know I'm not the only one who seems to be getting their butt kicked by this cocktail. Ugh!  

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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May 12, 2014 05:55PM Skoolgirljen wrote:

Has anyone had to deal with hot flashes on this cocktail? I'm not taking any hormone therapy, because my tumor isn't hormone receptor positive. No major sweats, just hot flashes pretty frequently. It's horrible on top of feeling crappy since my treatment on Friday.  I just had treatment 5 of 6, then on to surgery this summer. I can't wait to have this all behind me!

Dx 1/24/2014, IDC, 3cm, Stage IIA, Grade 3, 0/2 nodes, ER-/PR-, HER2+ Targeted Therapy 2/13/2014 Herceptin (trastuzumab) Targeted Therapy 2/13/2014 Perjeta (pertuzumab) Chemotherapy 2/13/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 6/30/2014 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery 11/20/2014 Reconstruction (left); Reconstruction (right)
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May 13, 2014 08:23AM Kite wrote:

Skool- I have night sweats really bad. Now I've only had one treatment so far so I'm not sure if it's the drugs but that's my guess. Round 2 is tomorrow. I remember after the first one I had to change my sheets because I was sweating so badly. My tumors aren't hormone positive either. 

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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May 14, 2014 07:17AM srdc2013 wrote:

Yes on the hot flashes for me too.  They don't cause me to sweat but it's like a fire gets lit all over - it's crazy!   

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May 14, 2014 12:23PM wifessupport wrote:

Yeah my wife has hot flashes. She finished her THCP regimen last week and she used to sweat a lot all of a sudden.  

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May 14, 2014 01:55PM Kite wrote:

yay for your wife!! How is she feeling now? 

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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May 15, 2014 06:17AM carolsue63 wrote:

I would wake up soaking wet the first few nights after TCHP, but luckily it stopped after that.

Dx 10/20/1997, DCIS, Stage 0, 0/8 nodes Surgery 11/16/1997 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 1/13/2010, IDC, 3cm, Stage IIB, 1/14 nodes, ER+/PR+, HER2+ Targeted Therapy 3/18/2010 Herceptin (trastuzumab) Chemotherapy 3/18/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 8/19/2010 Breast Dx 1/8/2014, Stage IV, ER+/PR+, HER2+ Targeted Therapy 1/14/2014 Herceptin (trastuzumab) Targeted Therapy 1/14/2014 Perjeta (pertuzumab) Chemotherapy 1/14/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)
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May 15, 2014 07:56AM Kite wrote:

I just had my 2nd round. So far the rash is stayed away. My eyes and nose are dropping like crazy though. Much worse then last time. My eyes actually sting and are very red. Hoping for no diarrhea! I'm getting my Neulesta shot today and going for a bag of fluids tomorrow. I've found that having those extra fluids really helps. I learned this little trick from my many trips to the ER. 

Dx 11/25/2011, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, mets, ER-/PR-, HER2+ Surgery 12/9/2011 Mastectomy: Left, Right Targeted Therapy 1/13/2012 Herceptin (trastuzumab) Chemotherapy 1/13/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 7/11/2012 Reconstruction (left); Reconstruction (right) Dx 2/19/2014, Stage IV, Grade 3, ER-/PR-, HER2+ Radiation Therapy 3/11/2014 Bone Targeted Therapy 4/23/2014 Herceptin (trastuzumab) Chemotherapy 4/23/2014 Taxotere (docetaxel) Targeted Therapy 6/4/2014 Herceptin (trastuzumab) Targeted Therapy Perjeta (pertuzumab)
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May 15, 2014 10:51AM carolsue63 wrote:

I'm with you, Kite. I was amazed how much it helped to get fluids! I discoveredc that on my 5th tx. I went in for fluids twice during the week after chemo. I'd get chemo on Friday, drink Gatorade all weekend, then get fluids on Monday when I went for my Neulasta shot, and again on Wednesday. It was kind of a pain, but oh so worth it!!

Dx 10/20/1997, DCIS, Stage 0, 0/8 nodes Surgery 11/16/1997 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 1/13/2010, IDC, 3cm, Stage IIB, 1/14 nodes, ER+/PR+, HER2+ Targeted Therapy 3/18/2010 Herceptin (trastuzumab) Chemotherapy 3/18/2010 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 8/19/2010 Breast Dx 1/8/2014, Stage IV, ER+/PR+, HER2+ Targeted Therapy 1/14/2014 Herceptin (trastuzumab) Targeted Therapy 1/14/2014 Perjeta (pertuzumab) Chemotherapy 1/14/2014 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)

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