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Mar 4, 2019 05:10PM
Well, my stats are deceiving and I've often wondered if I should change them. My tumor presented at biopsy at 1.5 cm and by the time I got to MD Anderson it was maybe 1.9 cm--but not large enough to qualify for Perjeta. When I set up my user profile here, I checked 1 cm+ but it shows up as 1 cm. Someone had asked the question recently on a different thread about the difference between MRI and ultrasound measurements and I will copy and paste my answer below because it gives you a pretty good idea of what went on with my tumor. It makes the PCR even more amazing if those numbers in late August are anything close to real.
My tumor was HER2 positive and was clearly exploding in growth at the time of diagnosis, but did it really grow from 1.5 cm to 7 cm in two weeks? Note below that in December I had an ultrasound on the 10th and an MRI on the 13th. The ultrasound measured the tumor's largest dimension as 8 mm and the MRI three days later measured it at 1.3 cm. My oncologist did the original MRI in August because he wanted me to qualify for Perjeta. Boy, did I! He looked pretty ashen the next time I saw him. Suddenly I not only qualified for Perjeta, but also radiation! I would say that, in my experience, based on the December imaging, MRI exaggerates.
8/15/18 Biopsy Ultrasound---1.5 x 1 x 1 cm
8/30/18 MRI----------------------7 x 2 x 3.4 cm (!!!!)
11/12/18 Ultrasound-----------1.1 x 0.6 x 0.4 cm
12/10/18 Ultrasound------------0.8 x 0.7 x 0.3 cm
12/13/18 MRI---------------------1.3 cm at largest point (radiologist did not record other 2 measurements)
Your wife receives treatment at MD Anderson or did she just get a second opinion there?
1997--dx Cystosarcoma Phyllodes, R breast, ½ mastectomy. 2018--dx IDC, L breast. 8/15/18 Biopsy US measurement: 1.5 x 1 x 1 cm 8/30/18 MRI measurement: 7 x 2 x 3.4 cm (!?!). I qualified for Perjeta very suddenly, and radiation.
8/20/2018, IDC, Left, Grade 3, 0/1 nodes, ER-/PR-, HER2+ (IHC)
9/11/2018 Perjeta (pertuzumab)
9/11/2018 Herceptin (trastuzumab)
9/11/2018 Carboplatin (Paraplatin), Taxotere (docetaxel)
1/31/2019 Mastectomy: Left, Right
2/27/2019 Whole-breast: Breast, Lymph nodes, Chest wall