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All TopicsForum: HER2+ (Positive) Breast Cancer → Topic: 1 Year of Herceptin Best for Lowering Recurrence Risk

Topic: 1 Year of Herceptin Best for Lowering Recurrence Risk

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Mar 30, 2017 10:53AM

Moderators wrote:

Long-Term Results Show 1 Year of Herceptin Best for Lowering Recurrence Risk of Early-Stage, HER2-Positive Disease
March 28, 2017

Eleven years of follow-up information from the HERA trial confirm that 1 year of Herceptin, rather than 2, is best for reducing the risk of recurrence in women diagnosed with HER2-positive, early-stage breast cancer. Read more...

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Mar 30, 2017 06:33PM moonchild64 wrote:

I check into the forums around this time every year - my cancerversary. The article you shared is confirmation that my MO and I made the right decisions at my diagnosis for my treatment plan in 2008.

I am so happy to report that I am now NINE years clear. No sign of recurrence and living life with a grateful heart.

Stay strong all BC sisters. We're all warriors!

TCHx4 9/2008, 35 rads, Herceptin x 17 6/2009, Tamoxifen beg. 1/2009, Tamox side effects - complete hysterectomy 6/2012. Dx 5/13/2008, IDC, 1cm, Stage IB, Grade 3, 0/4 nodes, ER+/PR+, HER2+
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Mar 31, 2017 04:04AM Moderators wrote:

moonchild, thank you so much for chiming in, and congratulations on your nine years NED!!

The Mods

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Mar 31, 2017 03:42PM Kimm992 wrote:

Love hearing from people who are so far out!! Thanks for coming back to share!

Dx 10/14/2015, IDC, Right, 1cm, Grade 3, 0/3 nodes, ER-/PR-, HER2+ Chemotherapy 11/2/2015 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Chemotherapy 1/6/2016 Taxotere (docetaxel) Targeted Therapy 1/6/2016 Herceptin (trastuzumab) Surgery 3/24/2016 Mastectomy: Right Radiation Therapy 4/30/2016 Lymph nodes, Chest wall
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Apr 21, 2017 01:21AM Drained6513 wrote:

Hi, I am diagnosed with Stage 1a, HER+ BC.  I did the 12 Taxol treatments.  One month since last one and am now on the Herceptin for a year.  Which I get every three weeks.  I've heard good things about Herceptin, but also some bad.  I've been told by my Ocologist that heart damage risk is rare, and the nurse also reassured me this.  Yet I've read on here some women have gotten permanent heart valve damage from it.  This has me scared now.  My BC was taken out... with left side mastectomy.  Besides all this, I am in excellent health.  I'm 55 years old.  I told my Ocologist that for me to do the Adjuvant Taxol and Herceptin I'd have to stay in good health.  There is no point for me to end up disable with a bad heart etc., as my Oncotype was low to start with.  I sometimes wish I hadn't done this at all.  Because it was low anyways. 

So, my question is, should I be overly concerned about taking this Herceptin?  I've had two echocardiograms and they were good.  I'm due for another one in a few months.  Does the echocardiogram catch valve problems etc?  Should I just get off this drug?

DX: Stage1A, Grade 2, Centinode 0/3 negative. With Pagets. Left side Mastectomy Nov. 4/16 with reconstruction. Suffered infection and expander removed Dec. 2016. Weekly Taxol x12 with Herceptin every 3 weeks for 17 weeks. ER- PR-, HER+
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Apr 21, 2017 04:37PM wabals wrote:

Drained

The oncotype scoring is not valid for Her2+ tumors. Not sure why you had it done.

Am 73 and went through a year of tdm1 (herceptin + chemo) with no problem. If you are concerned, see a cardiologist for consultation. That is what I did. My echos never changed. You really do need the herceptin.

Her2 is aggressive and not to be taken lightly

Dx 6/2015, IDC, Left, <1cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2+ (FISH) Hormonal Therapy Radiation Therapy Surgery Lumpectomy: Left Targeted Therapy Kadcyla (T-DM1, ado-trastuzumab)
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Apr 22, 2017 05:03AM Drained6513 wrote:

Wabals, thank you for your reply.  I am glad you are doing well.  How long have you been finished your chemo and Herceptin?  What chemo drug did you do?  Was it the weekly one?  What I've read on here is in some women 10 years later they ended up with CHF and the cardiologist said it was probably from the chemo?  I am seeing a cardiologist in about 2 weeks.  Going to be doing a 24 hour Holter Monitor and then talk with him when the results are in.  I have heart palpitations, but I had them before all this started too.  So, gonna have it checked anyways.  I feel funny on the Herceptin, with the heart palpitations and I have a dry cough occasionally with fatique.  The fatique is only usually a day or two after the treatment.  I get anxious sometimes, usually at night, when I'm laying down.  The heart palpitations don't help the matter, although I as stated my echocardiograms appear to be fine.  I hope it's all normal and not anything to worry about.  I just worry 10  years (less or more) down the road I end up with serious issues from these drugs?  There is a discussion board on here with a lot of women this seems to have happened to.

DX: Stage1A, Grade 2, Centinode 0/3 negative. With Pagets. Left side Mastectomy Nov. 4/16 with reconstruction. Suffered infection and expander removed Dec. 2016. Weekly Taxol x12 with Herceptin every 3 weeks for 17 weeks. ER- PR-, HER+
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Apr 22, 2017 11:56AM wabals wrote:

I am in the ATEMPT trial at Johns Hopkins. I finished a year of targeted therapy (tdm1) last Aug.

My cardiologist put me on metoprolol as tdm1 raised my heart rate and BP. Now I am off it. As long as your echos are good I would not worry. On these boards you read all kinds of stuff. If you have a good doc, follow their advice

Dx 6/2015, IDC, Left, <1cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2+ (FISH) Hormonal Therapy Radiation Therapy Surgery Lumpectomy: Left Targeted Therapy Kadcyla (T-DM1, ado-trastuzumab)

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