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Topic: Chemo Before Sx for Early HER2+ Doesn’t Need Anthracycline

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jun 4, 2020 01:20PM

Moderators wrote:

Have you been diagnosed with early-stage HER2-positive breast cancer and will be having chemotherapy before surgery? A study strongly suggests that an anthracycline does not have to be part of the regimen. Read more...

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Jul 8, 2020 11:04AM - edited Jul 8, 2020 11:08AM by Shar2020

Thank you, Moderators, for this informative article.

I have been given two chemo options for early stage two HER2 positive breast cancer. AC-T was strongly recommended over TC because HER2 positive can be aggressive and has a high rate of recurrence. (Whichever option I choose will also include a year of Herceptin.)

I asked for the rates of efficacy, survival and recurrence for the two options, but the oncologist and resident did not know. This article and additional research will help me make an informed decision.

Thank you.

Dx 6/1/2020, IDC, Right, 2cm, Stage IIA, Grade 3, ER+/PR-, HER2+ Targeted Therapy Herceptin (trastuzumab) Chemotherapy Carboplatin (Paraplatin), Taxotere (docetaxel)
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Jul 8, 2020 10:08PM Cowgirl13 wrote:

That is good news to hear as the anthracyclines are so hard on the heart also.

Be the kind of woman that when your feet hit the floor each morning the Devil says: 'Oh crap! She's up! Dx 5/28/2009, IDC, Left, 2cm, Stage IIA, Grade 3, 0/4 nodes, ER+/PR+, HER2+ Surgery 6/18/2009 Chemotherapy 8/3/2009 Carboplatin (Paraplatin), Taxotere (docetaxel) Radiation Therapy 12/21/2009 Hormonal Therapy 2/23/2010 Arimidex (anastrozole)

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