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Topic: Response to weekly taxol followed by 3 weeks herceptin-perjeta

Forum: HER2+ (Positive) Breast Cancer —

Testing, treatment, side effects, and more.

Posted on: Jan 27, 2021 06:49AM

Vee36 wrote:

hello ladies

I was dx with stage 2B IDC grade 3, one lymph node confirmed by biopsy: pet-ct and breast MRI, tumor size and 2.6 cm (er pr neg, her2 positive)

I started Dose dense AC but tumor shrank only 1 mm although lymph node decreased in half

I recently started weekly taxol with 3 w herp/perjeta and was wondering when did u start to notice shrinking of tumor in this regimen?

vee

Dx 10/4/2020, IDC, Right, 2cm, Stage IIB, Grade 3, ER-/PR-, HER2+ (IHC)
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Jan 28, 2021 01:22AM MinusTwo wrote:

Vee - your tumor may or may NOT shrink. Or the chemo may kill the cancer cells and you still have the shell/husk. Hope you're lucky and you do have pCR (complete response). I'm assuming they'll do some imaging and then you're eventually headed for surgery. Good luck

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Jan 28, 2021 03:34AM Vee36 wrote:

Thank u minus two, may i ask about your experience with taxol/herceptin/perjeta, did u feel ur tumor shrinking during and what was the residual left

Dx 10/4/2020, IDC, Right, 2cm, Stage IIB, Grade 3, ER-/PR-, HER2+ (IHC)
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Jan 28, 2021 12:05PM MinusTwo wrote:

I had a more robust chemo - TCHP. Taxotere, Carboplatin, Heceptin & Perteta infusions every 3 weeks for 6 rounds. Even at that, I did not have a pCR. The tumor was seen on imaging before surgery and then removed with clean margins, but because I was HER2+ my MO wanted to another round of chemo before radiation- AC. Adriamycin & Cytoxan. Then I had radiation & continued Herceptin for the balance of a year.

I'm now 7 years NED (no evidence of disease).

If you go to 'my profile', you can enter your diagnosis & treatment or plan to date. That way BCO members will have an easier time answering your questions.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014

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