Jul 26, 2021 04:58PM AlwaysMeC wrote:
I am HER2 positive, with a histologic notttingham grade 2. It may be that the cells don't look too abnormal and there is not a lot of division happening, which is why her grade is low. From my understanding they use the grade to determine how much radiation would help. I am still in neoadjuvent treatment, so there are probably members here that have more knowledge on that.
Chemo is usually recommended for HER2 prior to surgery. I think it also depends on size, but mine was 18 mm and the oncologist is being very aggressive, saying it's close enough to 20, so I could have Perjeta added to my treatment plan.
I am always a broken record when I bring this up, but try not to read research articles older than 5 or 6 years. There are so many advancements with HER2 that you will find outcomes have greatly improved in just the past few years. Older papers will worry you unnecessarily.
The treatment plan for ER+ and HER2 is different from mine, so hopefully another member will chime in.