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Topic: How common is a 2nd cancer in other breast?

Forum: Second or Third Breast Cancer — For those confronting a new primary diagnosis or undergoing treatment.

Posted on: Jan 7, 2011 03:46PM

sflow wrote:

Just when I was starting to feel good about being 4 yrs and 2 months out of Stage I IDC, I talked to someone last night that said, usually if you have BC in one breast, you get it eventually in the other.  This woman had early stage at 47 in right breast and in left breast at 54--does anyone know the statistics on this?

Dx 11/15/2006, IDC, Right, <1cm, Stage IA, Grade 3, 0/4 nodes, ER+/PR+, HER2- (IHC)
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Feb 5, 2020 10:26PM Beesie wrote:

Great info, MountainMia.

The following analysis is a bit older, covering 4,900 women between the years of 1992 to 2004. It indicates that the best case scenario is "double the risk" (of a woman who did not previously have breast cancer) for those with hormone positive breast cancer. For other breast cancer subtypes, the risk of a second primary may be substantially higher than that.

Second Primary Breast Cancer Occurrence According to Hormone Receptor Status

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720990/

"Women who had survived HR-positive breast cancers had more than a twofold increased risk of a second primary tumor, and women who had survived HR-negative breast cancers had nearly a fourfold increased risk, compared with the age-, race-, and year-adjusted general population. Those with HR-negative first tumors were much more likely to develop HR-negative second tumors, and this was especially true for women first diagnosed before age 30, who had 169 times the normal risk of a second HR-negative tumor."

“No power so effectually robs the mind of all its powers of acting and reasoning as fear.” Edmund Burke
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Feb 5, 2020 10:41PM MountainMia wrote:

Thanks for this link, Beesie. It doesn't make me feel better, having triple negative for a first diagnosis! (Scary stuff...)

The rain comes and the rain goes, but the mountain remains. I am the mountain.
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Feb 5, 2020 11:15PM Trishyla wrote:

Sending hugs, Mountain Mia. I sincerely hope tomorrow's results are completely benign.

Trish

Dx 8/30/2016, IDC, Left, 1cm, Stage IIA, Grade 2, 1/2 nodes, ER+/PR+, HER2- Dx 8/30/2016, IDC, Right, 1cm, Stage IA, Grade 3, 0/1 nodes, ER-/PR-, HER2- Dx 9/6/2016, IDC, Left, 1cm, Stage IIA, Grade 2, 1/2 nodes, ER+/PR+, HER2- Chemotherapy 9/28/2016 AC + T (Taxol) Surgery 4/4/2017 Lymph node removal: Sentinel; Mastectomy: Left, Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Chemotherapy 8/5/2017 Xeloda (capecitabine)
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Feb 6, 2020 11:31AM Jaybird627 wrote:

I had BC right breast at age 44, BC left breast at age 57. I am BRCA2+.

Jaybird ~

Jaybird. My hopes are not always realized, but I always hope - Ovid. Surgery 3/4/2005 Lumpectomy; Lymph node removal; Mastectomy; Prophylactic ovary removal; Reconstruction (left): Silicone implant; Reconstruction (right): Latissimus dorsi flap, Silicone implant Dx 3/5/2005, IDC, Right, Stage IIB, Grade 2, ER+/PR+, HER2-
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Feb 6, 2020 01:43PM MountainMia wrote:

Thanks to all of you for your good wishes. I had the follow-up US. Radiologist said the "mass" is collected fluid from my reduction surgery in November. He wants me to come back in 6 months, but was adamant that no biopsy is needed now.

So HOORAY!

The rain comes and the rain goes, but the mountain remains. I am the mountain.
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Feb 6, 2020 04:47PM Beesie wrote:

Yay!!! "Adamant that no biopsy is needed now" is great! Nerdy

“No power so effectually robs the mind of all its powers of acting and reasoning as fear.” Edmund Burke
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Feb 6, 2020 06:47PM MinusTwo wrote:

Mia - Great news. Thanks for sharing.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Feb 7, 2020 03:28PM KBeee wrote:

Great news!


Karen. Dx 8/5/2013, IDC, Right, 1cm, Grade 2, 0/1 nodes, ER+/PR+, HER2- (IHC) Surgery 8/26/2013 Mastectomy: Left, Right Chemotherapy 9/20/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 12/12/2013 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/23/2014 Reconstruction (left); Reconstruction (right) Surgery 1/29/2015 Lumpectomy: Right Dx 2/2/2015, IDC, Right, 1cm, Grade 2, 0/0 nodes, ER+/PR-, HER2- (FISH) Dx 2/25/2015, IDC, Right, 1cm, Grade 3, 0/13 nodes, ER+/PR-, HER2- (IHC) Surgery 2/25/2015 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary; Prophylactic ovary removal Chemotherapy 3/31/2015 AC + T (Taxol) Radiation Therapy 8/25/2015 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Femara (letrozole)
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Feb 7, 2020 09:58PM 7of9 wrote:

hip hip HOORAY! Love good news!

If you're going through hell, keep on going. You might get out before the devil even knows you're there. Dx 1/18/2012, IDC, Left, 2cm, Stage IIB, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 5/31/2012 Lymph node removal: Left; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery 10/31/2012 Reconstruction (left); Reconstruction (right) Dx 12/23/2015, IDC, Left, 2cm, Grade 2, 10/14 nodes, ER+/PR+, HER2- Surgery 1/18/2016 Lymph node removal: Left, Underarm/Axillary Surgery 1/18/2016 Prophylactic ovary removal Radiation Therapy 2/10/2016 Whole-breast: Breast, Lymph nodes, Chest wall Chemotherapy 3/31/2016 Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole)
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Apr 5, 2020 02:11AM LowcountryGirl wrote:

I had IDC in 2017, right breast. Lumpectomy, chemo, radiation and now arimidex. Yesterday I had an MRI and got a call back that they see something in the left breast. Reading everything I can and trying to stay positive but it's not easy. To make matters worse, the clinic is on shortened days due to covid-19 so they can't even call me again until Tuesday to try and set up a follow up ultrasound for some future date. Argh.

Dx 12/30/2016, IDC, Right, 1cm, Stage IA, Grade 2, 1/6 nodes, ER+/PR+, HER2- Surgery 1/23/2017 Lumpectomy: Right Chemotherapy 2/17/2017 Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Apr 5, 2020 08:08AM Jaybird627 wrote:

LowcountryGirl, hoping that it's nothing. Hang in there!


J~

Jaybird. My hopes are not always realized, but I always hope - Ovid. Surgery 3/4/2005 Lumpectomy; Lymph node removal; Mastectomy; Prophylactic ovary removal; Reconstruction (left): Silicone implant; Reconstruction (right): Latissimus dorsi flap, Silicone implant Dx 3/5/2005, IDC, Right, Stage IIB, Grade 2, ER+/PR+, HER2-
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Apr 5, 2020 10:24AM Celand wrote:

LivingLaughingLoving,

I was diagnosed with DCIS/IDC in my left breast in 2016 at age 51. I qualified for genetic testing because my Mom was diagnosed with breast cancer in her early 40's. My insurance coverage was 100% as well. I had wanted to get this done anyway before I was diagnosed because I am considered high risk because of my Mom's history and because I have two daughters (ages 26 and 29).

It turns out that I am BRCA 1 & 2 negative and addditionally the genetic counselor informed me that I was not predisposed to any other type of cancer! (Yet I still ended up with BC right) She concluded that my getting BC was a fluke! However, I think that I took birth control pills for too long - 30 yrs, so I have a feeling that may have been a cause of mine. (Could be other environmental causes but I will never know)

My getting this genetic testing done only tells half of the story for my girls as the genetic counselor told me that Dad can also pass this gene to offspring. She did tell me that my girls could get tested for only BRCA gene for about $200 and not the $5k that my full panel of testing cost my insurance.

I have offered to pay for this for my girls but at this point in time neither is interested. Maybe because mine was caught very early and because I underwent a lumpectomy, radiation and now taking Tamoxifen, they didn't witness me having to endure more extensive treatment had it been detected at a more advanced stage, the magnitude of this has not registered for them.

Colon cancer worries me just as much if not more for them as several relatives on my husband's side of the family have fought that beast.

So, to answer your concerns about genetic testing,

1. My girls were not pushed into a course of action, they were indifferent to the results, even though I am BRCA negative at this point in time.

2. They have not mentioned feeling more secure that since I don't have BRCA 1 or 2 that they will not get BC

I have told both of them that there is no rhyme or reason to who gets BC, one can have many risk factors yet never get it or have no factors but get diagnosed. I hope and pray that neither get diagnosed with BC, but if they do I know how to help them, if I am still around.

Celand

Dx 10/17/2016, DCIS/IDC, Left, <1cm, Stage IB, Grade 1, ER+/PR+, HER2- Surgery 10/28/2016 Lumpectomy: Left Radiation Therapy 12/14/2016 Whole-breast: Breast Hormonal Therapy Arimidex (anastrozole), Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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May 4, 2020 04:50PM KBeee wrote:

I did the COLOR Genomics test, which was $250. That's how I found my VUS in the CHEK2 gene. It later was verified through family testing when my mom was tested and found to have it.

Karen. Dx 8/5/2013, IDC, Right, 1cm, Grade 2, 0/1 nodes, ER+/PR+, HER2- (IHC) Surgery 8/26/2013 Mastectomy: Left, Right Chemotherapy 9/20/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 12/12/2013 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/23/2014 Reconstruction (left); Reconstruction (right) Surgery 1/29/2015 Lumpectomy: Right Dx 2/2/2015, IDC, Right, 1cm, Grade 2, 0/0 nodes, ER+/PR-, HER2- (FISH) Dx 2/25/2015, IDC, Right, 1cm, Grade 3, 0/13 nodes, ER+/PR-, HER2- (IHC) Surgery 2/25/2015 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary; Prophylactic ovary removal Chemotherapy 3/31/2015 AC + T (Taxol) Radiation Therapy 8/25/2015 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Femara (letrozole)
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Jun 10, 2020 08:28PM quinnie wrote:

Just thought I would reply in this forum. I had DCIS 12 years ago in R breast, ER and PR negative. Lumpectomy and radiation. Fast forward 12 years and developed IDC in L breast ER and PR positive. All genetic testing negative. Just unlucky twice although I have extensive family history of breast cancer. One never knows. I have 4 sisters who have never had cancer but many cousins, aunts, mom and grandmother.

Dx 11/30/2007, DCIS, Right, 1cm, Stage 0, Grade 2, 0/0 nodes, ER-/PR- Dx 2/26/2020, IDC, Left, <1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Radiation Therapy 5/14/2020 Whole-breast: Breast Hormonal Therapy 5/25/2020 Femara (letrozole) Radiation Therapy Whole-breast: Breast
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Jun 10, 2020 08:29PM quinnie wrote:

BTW, I was 51 when first diagnosed and 63 when diagnosed again.

Dx 11/30/2007, DCIS, Right, 1cm, Stage 0, Grade 2, 0/0 nodes, ER-/PR- Dx 2/26/2020, IDC, Left, <1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Radiation Therapy 5/14/2020 Whole-breast: Breast Hormonal Therapy 5/25/2020 Femara (letrozole) Radiation Therapy Whole-breast: Breast
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Jun 16, 2020 01:30PM mbtlcsw01 wrote:

Praying it is not so. Been off this site for over 10 years as I am an 11 yr survivor. I had IDC in right breast but opted for double mastectomy because my mom had this (and I found I was a BRAC 2 carrier). Fast forward to today, lump in left breast which had an ultrasound yesterday and bloodwork. Waiting to hear back from y oncologist to see what is next. Thanks for your postings. They have helped while I wait. Came back to BC.org because I knew this was the place to get support and help.

Mary Dx 10/16/2008, IDC, 1cm, Stage I, Grade 3, 0/2 nodes, ER+/PR-, HER2-
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Jun 16, 2020 02:26PM mac5 wrote:

just a FWIW. No idea which Statistical Group I fall into.

Diagnosed at age 60 with IDC and DCIS in left breast. Was told that chance of Recurrence was only 5% and if I got BC in the future it would be a “different kind.” Left Breast MX only.

Fast forward to age 69. Diagnosed with ILC in right breast. Qualified for Genetic Teasting because it was a recurrence. Tested 82 genes and NO abnormalities. Nothing. After MX on Right Breast diagnosed with both ILC and IDC from Pathology Report. And unable to get clear margins in chest wall.

I truly don’t believe there is much rhyme or reason to prove a lot of the Statistics we are given.

You just have to make your best guess with the information you are given at the time.

I had nine years not worrying about it. I’m good with that

Dx 7/20/2010, DCIS/IDC, Left, 2cm, Stage IIIB, Grade 2, 0/4 nodes, ER+/PR+, HER2- (IHC) Dx 9/5/2019, ILC/IDC, Both breasts, 6cm+, Stage IV, metastasized to lungs, Grade 1, 1/1 nodes, ER+/PR+, HER2-

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