Topic: final pathology changed after surgery

Forum: IDC (Invasive Ductal Carcinoma) — Just diagnosed, in treatment, or finished treatment for IDC.

Posted on: Mar 10, 2010 09:27AM

Posted on: Mar 10, 2010 09:27AM

zerp wrote:

I originally was diagnosed  with DCIS and Pagets of the nipple, same breast. I had a mastectomy and sentinel lymph node biopsy. Lymph nodes showed no sign of cancer. They found what they are calling infiltrating ductal carcinoma 1.4 cm in the tissue that was removed. Tomorrow I meet with an oncologist about what comes next. I am concerned because my ER and PR are negative, sounds like most women are positive. The report also said, MIB-1 fraction is approximately 30%??? Really don't know what that means! Anyone with a similar situation?  Thanks for reading.

Dx 3/9/2010, IDC, 1cm, Stage I, Grade 3, 0/3 nodes, ER-/PR-, HER2+
Log in to post a reply

Page 1 of 2 (16 results)

Log in to post a reply

Mar 10, 2010 10:15AM - edited Mar 10, 2010 10:16AM by irish47

Hi Zerp,

I had a 1.3 IDC tumour but was ER and PR positive.  Do you know your HER status?  If that is positive you will find lots of information on the tripple negative boards.  The best news though is that your lymph nodes are clear. Good luck with your meeting tomorrow!

Dx 1/13/2010, IDC, 1cm, Stage IB, Grade 1, 0/1 nodes, ER+/PR+, HER2-
Log in to post a reply

Mar 10, 2010 10:23AM - edited Feb 11, 2011 09:05PM by HeidiToo

delete

" It's not the years in your life, but the life in your years." (Abe Lincoln) Dx 8/11/2009, IDC, 2cm, Stage IIA, Grade 3, ER-/PR-, HER2- Surgery 9/8/2009 Lumpectomy: Right; Prophylactic ovary removal; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Chemotherapy 10/25/2009 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 1/1/2010 Breast, Lymph nodes
Log in to post a reply

Mar 10, 2010 04:33PM Ezscriiibe wrote:

It's not unusual for the pathology to change after the surgery. Mine did.

Best of luck to you going forward.

Michele ~ mets to liver; biopsy revealed that the cancer has mutated from ER+/PR+ to ER/PR - Dx 1/7/2010, IDC, 2cm, Stage IV, Grade 3, 0/1 nodes, mets, ER-/PR-, HER2-
Log in to post a reply

Mar 10, 2010 04:41PM navygirl wrote:

I think Irish means if your HER status is NEGATIVE you will find lots of information on the triple negative boards...

life is short, play hard
Log in to post a reply

Mar 10, 2010 04:49PM irish47 wrote:

Apologies, yes that is what i meant.

Dx 1/13/2010, IDC, 1cm, Stage IB, Grade 1, 0/1 nodes, ER+/PR+, HER2-
Log in to post a reply

Mar 11, 2010 07:29AM - edited Mar 11, 2010 07:29AM by Marion

Just like a lot of you, my lymph nodes pathology results changed as well.

It went from being negative (lymph nodes had no cancer) to positive (a 0.8 mm micro-met in one sentinel node). I had to go back for surgery, for an axillary lymph node dissection.

The hardest part was mentally. Going from feeling relieved (no cancer in lymph nodes) to realizing that lymph node involvement affected my survival rate. The worst part is that nobody had warned us that pathology results could change. The surgeon was sure there was no cancer in the lymph nodes.

Dx 7/23/2009, IDC, 1cm, Stage IIA, Grade 1, 1/14 nodes, ER+/PR+, HER2-
Log in to post a reply

Mar 12, 2010 06:47AM zerp wrote:

Well know now, chemo is in my future. With my er and pr negative, drugs were not a option. I worry about what I will  and won't be up for during chemo. I'm used to handling pretty much everything around the home, family, pets, yard and yes I have my own tools. So I'm not used to waiting for help if I can jump in and do it myself. This right now is probably the hardest thing to accept that I can't take care of my family the way I'm used to. I know they will survive but I still have guilt, this after all has been my job.

Dx 3/9/2010, IDC, 1cm, Stage I, Grade 3, 0/3 nodes, ER-/PR-, HER2+
Log in to post a reply

Apr 10, 2010 06:39PM lauriez wrote:

Hi Marion-I was dx with idc on 3/12. Since that time I have had an MRI guided biopsy, and more recently, a SNB. The MRI biopsy showed many areas of DCIS in addition to the idc, so it looks like I'll be having a mastectomy. I had the SNB on 4/7, which showed no CA-two were biopsied. I meet with my surgeon on Monday. I'm hoping she will have talked with the Onc. and rad onc to see what the plan is regarding chemo and rads. My cancer is grade 3. My question is regarding the change in pathology after surgery. I am already writing down my quesitons for the surgeon 1) how do you know if you got all of the sentinel nodes? 2) will you still take some axillary nodes at the time of the mastectomy? What was your experience with lumph node biospy? Thanks, Laurie

Laurie Age 48 left mx with TE 5/7/2010, port placed 6/2/2010, Dose Dense A/C every 2 weeks x4, then Taxol weekly x12. Tamoxifen x 5 years Dx 3/12/2010, IDC, 3cm, Stage II, Grade 2, 0/12 nodes, ER+/PR+, HER2-
Log in to post a reply

Apr 10, 2010 07:10PM - edited Apr 10, 2010 07:11PM by M360

Lauriez,  I'm sitting her full of stitches after two surgeries in two weeks.  I was originally diagnosed on 12/3 of IDC they said at that time it was only 1cm, so it was going to be take out the tumor and no lymph glands were involved there was a waiting list and I couldn't have my surgery until March.  No one seemed that it was a hurry.  Then in the end of February things changed.  I was told because the tumor was against my back wall I would have to have a mastectomy. I said fine. Then was told I couldn't have reconstruction because of autoimmune problems.  I was told I wouldn't be needing Chemo etc.  Well that was all wrong.  When they opened me up my tumor had grown to 3.9 and it had metastasized to my lymph glands. So they took out ten.  Then because so many had cancer they said auxiliary node dissection.  More had cancer.  Now they say Chemo etc needs to be started buy not until an infection that started in my chest heals.  I've been on IV antibiotics every three hours for two week and then 3,000 mg three times a week for two weeks starting this week.  What I found is that these procedures have to be done if you have positive lymph glands.  I read up all I could and studied the procedure.  However, they took out all my chest muscles and all muscle under my arm etc.  No one said they were going to take out that much, but surgeon said it was necessary.  I've realized that they really don't know the whole story til they take off the breast or cut out tumor, and how many lymph glands come back positive or path reports.   It's a step by step procedure to see how many and then how aggressive they need to be.  I've read printed out copies of each procedure but it doesn't really prepare you.  Each one of us is different and we all deal with it differently.  I'm wondering the same questions that you have.   How do they know they have them all.  Since surgeries I have  lymph glands on my other side the have grown to the size of quarters.  I worry that maybe some gene moved into other glands in my body.  That is why Chemo is so important, and also MRI and continued follow ups.  What I thought was going to be a couple of months is now going to be treatment for over a year.  So all you can do is be informed ask questions, but I don't think they always have the answers.  They take it a step at a time.  I'm someone who's pathology report changed so much in just three months.  Cancer is a crap shoot. It has a mind and works in it's own way, it's finding the right mixture and right treatment so that each one of us can survive.  Good luck to you.

Dx 12/3/2009, IDC, 3cm, Stage IIIB, Grade 3, 6/12 nodes, ER+/PR+ Surgery 3/25/2010 Lymph node removal: Left, Sentinel, Underarm/Axillary; Mastectomy: Left Chemotherapy 4/13/2010 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 10/26/2010 Femara (letrozole) Dx 12/12/2012, IDC, Stage IV, Grade 3, mets, ER+/PR+ Dx 1/29/2013, IDC, 2cm, Stage IV, Grade 3, 6/9 nodes Dx 2/16/2013, IDC, Stage IV, Grade 3, mets, ER+/PR+ Hormonal Therapy 2/27/2013 Faslodex (fulvestrant) Chemotherapy 4/1/2013 Cytoxan (cyclophosphamide), Xeloda (capecitabine) Chemotherapy 6/18/2014 Doxil (doxorubicin) Chemotherapy 9/24/2014 Abraxane (albumin-bound or nab-paclitaxel)
Log in to post a reply

Apr 10, 2010 07:48PM lauriez wrote:

M360-thank you for sharing your story. I'm so sorry that things progressed so rapidly for you. It must be horrible to deal with all of the muscle loss you have described. I'm so sad for you and hope that you recover quickly from your surgery.

I've had a gut feeling all along since my diagnosis (not before), and I've not been wrong. I should be elated at the neg node status, but I'm not. I'm not a pessimistic or negative person, I just don't trust it. Well I'll listen to what they have to say on Monday and go from there. Thanks again for your response.

Laurie Age 48 left mx with TE 5/7/2010, port placed 6/2/2010, Dose Dense A/C every 2 weeks x4, then Taxol weekly x12. Tamoxifen x 5 years Dx 3/12/2010, IDC, 3cm, Stage II, Grade 2, 0/12 nodes, ER+/PR+, HER2-

Page 1 of 2 (16 results)

Scroll to top button