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BRCA2 negative and now positive
Hello, I was first diagnosed in 2015 with early stage IIb. I had genetic testing done at the time and was negative for all mutations including BRCA1 and 2. I had a recurrence in 2022 and I had the Caris test done on the tumor and again no BRCA found. Just within the last month I had a PET scan turn up some swollen lymph…
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Important Stage IV Topics and Links for Stage IV Newbies
Here are some helpful resources if you've just been diagnosed with stage IV breast cancer, also known as metastatic or MBC. Join our Zoom Meetups for MBC! Anyone with MBC, register here: Mondays 2 pm ET Tuesdays 8:30 pm ET Wednesdays 4 pm ET Younger With MBC, register here: Thursdays, bi-weekly at 1:00 PM ET Great tips,…
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Beginning Targeted Therapy? Start here.
Please start a new post/discussion for a targeted therapy that you'd like to discuss, if you don't see it here already, so others can join in with their experiences. Note: If you are Stage IV (metastatic), there are many threads addressing these medications for Stage IV patients in the Stage IV forum you may find helpful.…
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Lynparza Approved To Treat High-Risk, Early-Stage, HER2-, BRCA+
Lynparza Approved To Treat High-Risk, Early-Stage, HER2-Negative Breast Cancer With BRCA Mutation Mar 13, 2022 The FDA approved Lynparza to treat early-stage, HER2-negative breast cancer with a BRCA1 or BRCA2 mutation and a high risk of recurrence, which also has been previously treated with chemotherapy — either before or…
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I am lost and scared that my next option is chemo. Emotional Yo-Yo and I have chemo PTSD
Hi there i just need to vent my fears. Not even 2 years with MBC and i am about to quit all treatments. Emotional Yo-Yo takes tall. Back in 2016 chemos were rough but i was going for the win. But this time around is different. There is no end of treatment and there is no win per se. I am lost and scared that my next option…
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Treatment After CDK4/6 Inhibitors
Treatment After CDK4/6 Inhibitors Dec 5, 2023 Medical oncologist Stephanie Graff explains the treatment options available after a CDK4/6 inhibitor stops working. CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer. The CDK4/6 inhibitors are: Ibrance…