Recently diagnosed, Assistance with terminology.
I recently received a wide local excision and sentinel lymph node biopsy on my right breast. Final report reveals I have invasive cancer.
Notes as follows:
TNM Stage Classification: pT2N0 (sn) Mx
ER: Positive. 2+ to 3+ staining 90% of cells.
PR: Positive. 2+ to 3+ staining 80% of cells.
HER2: Negative (1+)
Ki-67: Approximately 40%
LYMPH NODES: One lymph node with no evidence of metastatic tumour.
Invasive tumour: 0.9mm from superior, 3.5mm from medial, 5mm from superficial, 8mm from lateral, 10mm from the inferior margins.
Here is the apparent controversial area according to my breast surgery team, two out of three surgeons felt I don't need further surgery but one preferred I have an additional surgery due to my DCIS margins before chemotherapy. An additional surgeon wants me to have chemo than an MRI and no further surgery yet.
DCIS: <0.1 from deep and superficial, 0.5mm from superior, 1.5mm from lateral, 3.5mm from medial and 5mm from inferior margins.
The surgery team want my decision tomorrow at latest. I realise this is a forum and the decision is mine, personally I don't wish to have additional surgery but I wouldn't mind your opinion?
HISTOLOGICAL TUMOUR TYPE: Invasive carcinoma of no special type
SIZE OF INVASIVE TUMOUR: 33mm
WHOLE SIZE OF TUMOUR (INVASIVE +DCIS) 60mm
EXTENT OF TUMOUR: Focal
ASSOCIATED DCIS: Present. Intermediate and high nuclear grade solid and comedo types
ASSOCIATED LCIS: Not identified
PERITUMORAL LYMPHOVASCULAR INVASION: Not identified
Tumour cells show moderately pleomorphic, hyper chromatic nuclei and eosinophilia cytoplasms and frequent mitoses. The BRE grade is 3 (tubules 3, nuclei 2, mitoses 3, with 25 mitotic figures identified within 10 high piwer fields).
it's a little confusing, the terminology is way beyond my pay grade, um, I guess I don't understand why chemo is so strongly recommended, one surgeon said my age (48) and superior fitness levels suggest I'm a good candidate for chemo, radiation and hormone therapy since I'm so active and healthy.
My concern is, won't all these procedures kind of destroy my health? Um, I'm a little anxious, I have been told my cancer is “favourable" and that I'll be fine - interesting
So, I mean, what do you guys make of the report. I read a lot about side effects from chemo and tamoxifen, although I don't know what sort of medicines I'm to receive yet. My palms are sweating, if you know what I mean.
Anyway, I'd appreciate any input.