What do these numbers mean?

Fitmom04
Fitmom04 Member Posts: 40

what do these numbers mean?

Left breast ultrasound guided biopsy with clip placement at 10 o'clock, 7 cm from the nipple with pathology showing invasive mammary carcinoma, Nottingham grade 2 out of 3. ER low positive, PR negative, HER - 2 equivocal, FISH performed. Ki 67 = 5%.

Comments

  • melbo
    melbo Member Posts: 266
    edited August 2022

    here is a short article describing the Nottingham score — but it’s essentially helping the doctors determine the “grade” of you cancer. The grade describes the expected aggressiveness — with grade 1 cancers being less aggressive and grade 3 cancers being more aggressive. The grade, along with other characteristics — such as the size of the tumor, the ki67 score, and whether it’s positive or negative for ER, PR, and HER2 — help the doctors decide on the best treatment plan for your specific cancer.


    hope that helps!


    https://www.oncolink.org/frequently-asked-questions/cancers/nottingham-score-for-breast-cancer

  • kaynotrealname
    kaynotrealname Member Posts: 274
    edited August 2022

    Your tumor tested positive for estrogen receptors although not a high positive, negative for progesterone receptors, and you are waiting for confirmation on whether you have enough HER2 receptors to qualify as a HER2+ positive tumor. Your Fish score will determine that and you will probably receive it back in a couple of days. Your Ki 67% is low which is considered positive although not all labs test for it. But it can mean your tumor isn't growing that fast. With a low ER positive tumor you'll qualify for endocrine therapy and that is also considered positive.

  • Fitmom04
    Fitmom04 Member Posts: 40
    edited August 2022

    thank you

  • Fitmom04
    Fitmom04 Member Posts: 40
    edited August 2022

    endocrine therapy