Fill Out Your Profile to share more about you. Learn more...

Anastrozole (again)

suzare Member Posts: 33
edited September 2022 in Bone Health and Bone Loss

I have been on Anastrozole for nine months now and I am struggling terribly with the side effects. I barely sleep due to the drenching night sweats and the itch and burning on my skin. Nausea, vomiting and diarrhea are constant, plus advancing Osteopenia -- just one value away from Osteoporosis. My Oncologist asked if I wanted to try another AI, but they all have tough side effects and I would rather stay with the devil I know. I read that Gabapentin can help with the night sweats -- has anyone tried that and was it helpful?


  • exbrnxgrl
    exbrnxgrl Member Posts: 4,747
    edited September 2022


    Although all of the AI’s can potentially have the same se’s many folks find that if they switch they experience lesser se’s or none at all. I have tried all three and settled on Aromasin (Exemestane) . I still have some se’s but I can tolerate them and I sleep like a log! I will add that I am stage IV so am 110% motivated to stay on them as I have been NEAD for 11 years. Consider a switch as that might just do the trick! Take care

  • dulcea
    dulcea Member Posts: 96
    edited September 2022

    suzare - I too have tried two AIs and letrozole was AWFUL!! I have been on arimidex 18 months and it seems that my biggest issue is thinning hair. I don't notice anything else. I did have a really bad arthritic flair about eight months in which I think was actually due to new cholesterol meds. Thankfully, that has subsided since stopping the cholesterol medications. I don't think I could tolerate the side effects you have! Try another AI and see what happens.

    exbrnxgrl - best wishes for continued health!