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Stage 111 and almost 6 years on hormone therapy

toughcookie Member Posts: 5
edited August 2023 in Stage III Breast Cancer

I’m about six years cancer free. I had a bilateral mastectomy with 14 cancerous nodes, rads and chemo, and my onc recommended I continue hormone therapy for another four years for a total of 10. I’ve switched back and forth between letrozole, exemestane and tamoxifen due to side fx. I lasted almost 4 years on tam but last fall the hot flashes, weakness and fatigue was too debilitating took a break for a few months and then decided to try exemestane again. This time the joint pain wasn't too bad but I’m now into my third month and the hot flashes are increasing as well as the fatigue along with insomnia, depression and anxiety/worry. I’ve never experienced anxiety like this in my life. Sometimes I don’t even want to leave the house! I’m seriously considering quitting HT. I know I have a high risk of recurrence with 14 cancerous nodes but my life is miserable. I don’t have a family but I do have pets and want to be around for at least another 7-8 years to ensure I outlive them. Has anyone else who was stage 3 ended their hormone therapy and lived to tell the tale five plus years on?


  • elainetherese
    elainetherese Member Posts: 1,624


    Can you get your onc to run the Breast Cancer Index (BCI) test? That can test your tumor to determine whether or not it will benefit from additional hormone therapy. Also, when exemestane made me moody, my onc prescribed a low dose of Celexa which did the trick.

    I did eight years of exemestane + Zoladex but quit after the BCI test said that I wouldn't benefit from additional hormone therapy.