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Teaching the Immune System to Fight Cancer

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edited September 13 in Clinical Trials, Research News, Podcasts, and Study Results

Aug 22, 2025

A new type of drug may be able to make the immune system attack cancer. Dr. Benjamin Schrank explains his research.

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Antibody-drug conjugates (ADCs) are a relatively new type of medicine for breast cancer. Enhertu (chemical name: fam-trastuzumab-deruxtecan-nxki) and Dato-DXd (brand name: Datroway) are two ADCs used to treat breast cancer.

Dr Benjamin Schrank and colleagues have developed a new type of ADC that combines an antibody with a toxin — called an antibody-toxin conjugate — that teaches the immune system to recognize and attack cancer cells.

Listen to the episode to hear Dr. Schrank explain:

  • the antibody and the toxin component of the medicine
  • how the new medicine works
  • possible side effects
  • next steps for the research

Listen now or read the transcript.

Episode image photo credit: The University of Texas MD Anderson Cancer Center

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