TRIPLE POSITIVE GROUP
Comments
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WOW Lago - your poor mom. Holy cow. There is SUCH a need for long term care in this country, and with the baby boomers aging...I cant even imagine what's coming down that pike.
Jerseygirl - not a bad idea to have doctor intervene if it gets overwhelming. I earned the cancer card, might as well play it occasionally lol.
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geewhiz I do have long term care insurance. It just went up last year but still worth every penny. I got it when I was 49 under my dad's former employer's group plan so still pretty reasonable. I have no kids and I'm younger than my husband who smokes. Granted I'm the one who got cancer.
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Today was one of the best days I ever had. My daughter had her baby and I got to stay and was there in the delivery room.I can't stop crying for once it is a very happy cry.
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Your grand baby is beautiful Angie
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ANG!!! What a blessing! I am so happy for you, I got teary! Beautiful baby. Congratulations, enjoy every delicious moment.
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congrats, she is beautiful, enjoy the endorphins.
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What a beautiful grandbaby! Thanks for sharing. Congrats to you and your family!
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Thank - you everyone . Just thought I would share some good news .
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She's a beauty, ang! Congrats!
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that is indeed a beautiful baby! Congratulations!
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ang - congrats to you and your family! Thanks for the picture - beautiful!
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Hugh congratulations to you Ang on the arrival of your grand-daughter, she is absolutely beautiful.
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Congrats on your grand baby ang. such a cutie!
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Ang - congrats on the beautiful Grandbaby. So happy for your blessings!
PMR53
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Ang - congrats on the beautiful Grandbaby. So happy for your blessings!
PMR53
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Ang wow how cuuuuuute!
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Again thanks everyone the little one already comes home today!!! I'm so excited
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Hi all~ It's been a very long time since I've been on the boards & I'm seeking your expertise for a friend of mine just recently diagnosed. She has Stage 1 triple positive IDC, 0.7cm, 0 node involvement. Her MO is recommending 2 rounds of chemo + Herceptin, followed by radiation. I am confused about this as it appears the NCCN does not recommend chemo?
In addition, the MO quoted her a recent study that just came out that involved 1000 women over 10 years (started in 1990) BUT the women were ER/PR+ and HER2- AND had (+) node involvement. Are any of you familiar with this study? Can you help me understand why the MO is recommending chemo at such an early stage with no node involvement?
Thanks for sharing your knowledge!
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c-squared - her treatment is driven by the Her2+ aspect, and chemo/Herceptin is usually recommended for anything over .5cm, so her onc is recommending recognized protocols. I am not sure what is meant by two rounds though - and for smaller Her2+ tumors many are now doing Taxol/Herceptin for 12 weekly for 12 rounds, then Herceptin for the balance of the year. Here is some info about Taxol and Herceptin:
http://www.breastcancer.org/research-news/herceptin-plus-taxol-reduces-recurrence
Page 40 of the patient version of the NCCN guidelines states that tumors greater than .5cm may be treated with with chemotherapy and Herceptin.
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Congrats ang7894!
I'm joining this group as well since after my surgery my onco had my lymph node tissue retested for ER/PR and it came back 99% ER positive and (some lower percent [47%?]) PR positive. On my previous biopsies (node and breast tumor) all came back HER2 positive and ER/PR negative. Strange, but I guess false negatives happen because the sample is smaller on the biopsies. So now in addition to Herceptin till December, I'm also taking Tamoxifen (5 years).
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SpecialK~ Thank you so much for your response! The "two rounds" is what the MO is recommending AC <and> T although the study that he quoted showed no difference between recurrence rate for T alone vs. AC + T. Herceptin is included in both regimens, of course. If she has the AC + T now would she still be a candidate for it in the future?
Thanks Again!
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c-squared - there is a lifetime max limit on Adriamycin, and to me (I am not an oncologist!) it is overkill for a mass less than 1cm. I would personally elect a milder regimen with Herceptin.
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I'm sure everyone is aware of the upcoming ASCO cancer conference at the end of this month.
Abstracts were just released to the public. Among them were a couple dedicated towards the HER2 inhibitor, ONT-380, developed by Seattle, Washington based Oncothyreon.
There is investor interest in the company stock [ONCY], as it jumped 75% over the past two days. It might be nothing, since many of the investors are simply speculators with a mob mentality leading to irrational exuberance. BUT, there may be value with this new HER2 inhibitor.
It will be interesting to see what they say about these trials during the conference in two weeks.Here are those ONT380 abstracts:
1. ONT-380 in the treatment of HER2+ breast cancer central nervous system (CNS) metastases (mets).
URL: http://abstracts.asco.org/156/AbstView_156_151078.html2. Phase 1b study of ONT-380, an oral HER2-specific inhibitor, in combination with capecitabine (C) and trastuzumab (T) in third line + treatment of HER2+ metastatic breast cancer (MBC).
URL: http://abstracts.asco.org/156/AbstView_156_148081.html0 -
forgive me if this has been previously discussed but did or are any of you receiving hormone depression drugs while receiving neoadjuvant chemo such as TCHP to achieve PCR?
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steph - there are only a few that post here that have done TCHP so far, but hopefully they will chime in - did you ask this question on the TCHP threads? Is this something you are curious about or is it being recommended as a way to boost the chances of PCR?
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Steph, I had TCHP and was not menopausal or peri-menopausal when diagnosed, and I did not receive any hormone suppressors.
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did you recieve pcr Cassie?? I am just doing some research I saw karmanos is doing a trial giving hr and her2 pos hormone depression to reach pcr from what I've read triple pos do not get pcr as often as hormone neg do when I asked my oncologist about this she said I'm not worried about it you will get a good response..I am kicking myself I wanted a 2nd opinion but I also wanted to get started there are so many what ifs and I don't want this to come back.So far I am impressed with my results since I can no longer palpate my once very palpable tumor but that doesn't neccessarly mean I will achieve pcr
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hi ladies, hope all of you are doing well. I have a question for you. How long did you take herceptin? My understanding was that herceptin was taken for one year (or equivalent dose) and that would start with the first herceptin we took which was together with other chemo drugs. For example I started tchp in August 14' and was expecting to be done around aug 15. Where I had my infusion this week I asked the nurse, she checked up on my chart and said I was prescribed 17 only herceptin infusions of which I have received 7, so it would be mid December when I am done. I was really bummed as I recall onco saying I would do one year and had a few months left during my last visit. I will see him again at the end of this month but I wanted to ask you in the meantime. Thank
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I think most of us were prescribed herceptin for one year, which works out to about 16 or 17 total herceptin infusions. I had 16 total, 6 with chemo and 10 alone.
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my daughter decided to find out if she is genetically predisposed to this terrible disease, she is 33, my youngest daughter and has 2 babies under 6. When she went to the genetic test center in Boston ma. They were not too concerned about my BC diagnosis, as they were in her fathers melanoma Dx and his mothers ovarian issue? They said if she was triple negative then they were more concerned, what am I missing here? It's bad enough that we have this, but because she is to young, they weren't concerned yet? I know a few people under 35 that already have this disease, what gives? Am I wrong?
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