Pik3ca E110del mutation? it's rare
anyone have a PIK3CA E110del mutation? I do. it's rare, like 1 in 4000 Pik3ca mutation is E110del. it kept me out of a clinical trial because I didn't have one of the top 10 mutations. arghghgh. we're going to try Piqray anyways. arghagrhgargharghghhgh.
Same thing happened with my ESR1 mutation as well. I guess I'm extra-special.
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piqray was rough, had to quit after just a few weeks due to diarrhea, dehydration and kidney injury. On Truqap now, seems to be working well.
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Still on Truqap/fulvestrant but some minor progression is happening. I have a feeling after next PET scan that I will be on to a new med. Truqap is tiring. Ritalin helps.
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@kkcita Hello, I also took Truqap for 6 months which I had to stop due to progression on the PET scan. I tolerated it well. As I already have several lines of treatment behind me, I was offered oral chemotherapy, Xeloda, which I have been taking for 6 months and which suits me very well. Last pet scan in March ok, I'll do a new one at the beginning of July.
These changes in treatment are never easy; they require a lot of adaptation. I'm thinking of you very much. Please keep us posted on the progress.0
