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Nervous about switch from Letrozole to Exemestane

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Comments

  • canarycat
    canarycat Posts: 168

    yes I understand going to exemestane needs a longer washout as it’s a different type of AI than anastrozole and Letrozole.
    I also understand different countries have different protocols. I’m in Canada. 🇨🇦

    Just waiting for the pharmacy to call. Which I expect sometime this next week.

  • @canarycat Interestingly, when I asked my onc team about taking a break from Anastrozole before starting Exemestane, I was told to just make the switch immediately. (I live in the states).
    Hope that your transition goes smoothly.
    Hugs, Pam 💗

  • canarycat
    canarycat Posts: 168

    @livinglifenow interesting. I’m thinking it’s exemestane to other AI that needs the longer wash. I’m hoping I tolerate anastrozole. But if not I’ll be joining you with exemestane. Have a great day.

  • canarycat
    canarycat Posts: 168

    still waiting to hear from BC Cancer pharmacy. I’ll call them on Monday if I don’t hear anything tomorrow. I was planning on starting them after my trip to the mainland which is this weekend. Short trip. Going to my 50th High School reunion. How time flies!!!!

  • cardplayer
    cardplayer Posts: 2,086

    I started exemestane on 7/31. My bloodwork on 8/12 was good, but subsequent bloodwork (3 separate tests) showed elevated ALT and AST. I’m following up with my PCP, but read that exemestane can cause elevated liver enzymes. Anyone else have this experience?

  • No Zometa today.
    Hi ladies, one of my dearest friends came to take me to my Zometa infusion and stay with me through the first couple of days pos-infusion. I usually get flu-like symptoms and massive brain fog. Of course the sciatica makes driving longer than 15 minutes true agony.
    I’ve restarted my letrozole and the UTI symptoms are back. Well they may not be symptoms because my white blood cell count was high enough that the PA decided not to go ahead with the Zometa infusion today. Did you know that being on letrazole can result in frequent UTIs and urinary incontinence? The lack of estrogen weakens the urethra and the pelvic muscles. So she gave me an estradiol cream to treat the urethra. No switching off letrozole yet. It’s still the “best choice” for my diagnosis.
    So I still have 2 Zometa infusions to go and still on letrozole.