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Start Here: Important Links and Info About Hormonal Therapy
For some extensive information, see the main Breastcancer.org site's section on Hormonal Therapy, including detailed information on: What Is Hormonal Therapy? Is Hormonal Therapy Right for You? Types of Hormonal Therapy Treatment: Aromatase Inhibitors Arimidex: Benefits, Side Effects and More Aromasin: Benefits, Side…
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Podcast: Giredestrant Promising New Treatment For Early-Stage HR-Positive Breast Cancer
Giredestrant Promising New Treatment For Early-Stage HR-Positive Breast Cancer December 10, 2025 After surgery, many people with stage I to stage III hormone receptor-positive breast cancer take tamoxifen or an aromatase inhibitor for five to 10 years. This has been the standard of care for the last 25 years. At the 2025…
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Letrozole and Tendonitis?
Hello all! I am coming up on 6 years of AIs with Letrozole being the most recent one. I had been on Arimidex but developed trigger thumb and fatigue over time so I switched to Letrozole. I have been okay for the most part but I now have tenosynovitis in my left wrist which won't go away and a new tendon issue on the top of…
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Tamoxifen side effects
Hi, I am a 69 year old diagnosed with Stage1 HER 2 + ductal carcinoma 4 years ago. Ive been taking Tamoxifen for 3 years post lumpectomy for removal of a lump less than 1 cm. Lymph node testing was negative. I completed Radiation, but no chemo was recommended. Genetic testing negative and no family history. I have…
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I FEEL DIFFERENT
Im at a fork in the road. Is my Tamoxifen causing depression, lack of sleep, and being SO F'ing TIRED? or is it due to other things going on in my life? Do I need a Doctor or a Therapist…. That is where I am. I am 4 years in with Tam. Mentally, I am usually strong, outgoing, on the go but I have been…. well, not that…
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Anastrozole
Diagnosed in July 2025 with Invasive DCIS Stage 1 Grade 0 - 8 mm. Lumpectomy and 3 weeks radiation. No cancer. Oncologist wants me to take Anastrozole for 5 Years. Side effects are keeping me from not taking the drug. Can anyone share experience with this drug?
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Leg Cramps with Femara?.....
Hi Ladies, I am 2 months into Femara and Eligard (Lupron). The Hot Flashes are back! I am having lower back pain and front pelvic pain both of these are normally when I first wake up. Last night I flipped and flopped all night like a fish! Back hurt all night long. Also the past 4 nights I keep getting leg cramps. I keep…
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Doing Well on Aromatase Inhibitors (AIs)
I read a suggestion that someone should start a topic for women who are NOT experiencing severe SEs while taking Arimidex, Femara, or Aromasin. I'm about to start taking Arimidex and when I read about the potential SEs I get discouraged. Maybe others would also like to hear about positive experiences. We would love to hear…
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Irritability with Letrozole?
Is anyone else dealing with high irritability and low frustration tolerance while taking Letrozole? I'm usually an easy-going person. I ended up in a full-fledged tantrum this weekend over something really stupid. This is so outside my normal behavior, and it's starting to negatively impact my life. Has anyone else dealt…
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Looking for others with low risk, less than 2cm, IDC stage 1 grade 1HR+ HER2- on endocrine therapy
Are you like me? What endocrine therapy did you follow or are you following? Pre- or perimenopausal, stage 1, grade 1, low risk, node-negative, no genetic risk, screen detected ladies, let's hear from you! What were you prescribed and how have you changed it up over your therapy? What has worked for you? I've seen four…
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Side effects from aromatase inhibitor other than joint pain.
I started on Anastozole (Arimidex) a little over a month ago. I know there are two others that are often given to post-menopausal HR+ women, Aromasin (exemestane) and Famara (letrozole). The joint pain and menopause like symptoms are what are mentioned most in articles. Although I've had some wrist pain, which I understand…