BRCA2

Hello, I'm 27 and I've been diagnosed with both the BRCA2 and PALB2 gene that puts me at increased risk, and has made me worried to increase further risk by taking contraceptive pills. Has anyone else avoided birth control pills due to breast cancer risk, or is it negligible? This is my first post, sorry if I missed any…

Lynparza is a PARP inhibitor used to treat breast cancer in people with an inherited BRCA mutation. A small study found that Lynparza could also treat metastatic breast cancer in people with an inherited PALB2 mutation or who have breast cancer that has developed a BRCA mutation over time. This means that many more people…

Hi, I would like to know if some one takes part in this trials? Is Camizestrant better medicine than letrozol? Are there people who take it?

Hello and thank you for the existence of this resource I'm a 40 year old, triple positive, stage 2. I am awaiting my last chemo round on the TCH regimen. I decided to first start with a lumpectomy, as I was hoping at the beginning of my cancer journey that I would not need chemo. I also chose surgery first because it was…

So my Mum had peritoneal cancer and found out she had the BRCA2 alteration. That's how I have just found out that I have inherited it through genetic testing. We have no history of breast cancer in the family as far as we know, however the Dr's told my mum that they could see that her cancer had developed from her ovaries…

Breast Cancer Survivors With BRCA Mutation Have Higher Risk of Second Cancer Jan 16, 2025 Risks were higher for a new cancer in the opposite breast, as well as ovarian, pancreatic, and prostate cancers. Read more…

Hello, I was first diagnosed in 2015 with early stage IIb. I had genetic testing done at the time and was negative for all mutations including BRCA1 and 2. I had a recurrence in 2022 and I had the Caris test done on the tumor and again no BRCA found. Just within the last month I had a PET scan turn up some swollen lymph…

Breast Cancer After Childbirth and Survival in Women With BRCA Mutation Jul 15, 2024 Does being diagnosed with breast cancer after giving birth affect survival? Read more…

Fertility Treatments Safe for Survivors With BRCA Mutations Jun 11, 2024 Assisted reproductive technology doesn't increase the risk of breast cancer coming back in young women with BRCA mutations and a history of breast cancer. Read more…

Genetic Mutations More Likely in Breast Cancer Found Between Mammograms May 15, 2024 Having a family history of breast cancer and a mutation in any of the five main breast cancer genes may increase the chance that you may discover breast cancer between your routine mammograms. Read more…

I was initially diagnosed with a small DCIS. The plan was a lumpectomy with radiation therapy. Genetic testing, BRCA2+ gene mutation, strong family history, and the size of the DCIS measuring 65mm - the plan changed! A BMX with immediate DIEP Flap was the plan. Still a 'Stage 0'. The Plastic Surgeon changed the plan to a…

Lynparza Approved To Treat High-Risk, Early-Stage, HER2-Negative Breast Cancer With BRCA Mutation Mar 13, 2022 The FDA approved Lynparza to treat early-stage, HER2-negative breast cancer with a BRCA1 or BRCA2 mutation and a high risk of recurrence, which also has been previously treated with chemotherapy — either before or…

if you removed your ovaries and uterus because of genetic testing do you have any regrets or are you happy? What was your experience. My daughter is having a very difficult time making this decision. She has decided on extra screening for breast cancer but all doctors are urging her to remove ovaries now. Thank you for…

ASCO and SSO Update Genetic Testing Guidelines for People With Breast Cancer Apr 8, 2024 Updated guidelines say anyone age 65 or younger diagnosed with breast cancer should have genetic testing for BRCA1 and BRCA2 mutations. Read more…

Ovary Removal, MRI Screening for Breast Cancer Saves Lives in Women With BRCA Mutation Mar 18, 2024 Women with a BRCA1 or BRCA2 mutation have a higher-than-average risk of breast and ovarian cancer. Two preventive strategies may reduce the risk of death among women with these mutations. Read more…

I've been searching everywhere to find a peer to peer group, to maybe find someone who has been diagnosed with my same form of breast cancer as I figure out what treatment path to take. I was diagnosed with TNBC on September 18th. I have since been on a whirlwind ride of getting doctors to respond etc. Here are my details:…

Pregnancy Safe After Breast Cancer in Young Women With BRCA Mutation Dec 13, 2023 Having a child is safe for both mother and baby if women with a BRCA mutation get pregnant after a breast cancer diagnosis. Read more…

I found out that I had IDC and then through genetic testing, found out I have the BRCA2 mutation. After research and multiple discussions with surgeon and oncologist, I have decided to have lumpectomy and sentinel node biopsy at this time. Now waiting for pathology report and will do every 6 month surveillance. Have others…

Preventive Removal of Ovaries, Fallopian Tubes Linked to Better Survival in BRCA-Positive Breast Cancer Oct 25, 2023 Removing the healthy ovaries and fallopian tubes improved survival in women with a BRCA mutation who were diagnosed with breast cancer. Read more…

At-Home Genetic Tests Miss Many Mutations Aug 15, 2023 Genetic tests that you can take at home miss more than 90% of BRCA mutations linked to cancer in people without Ashkenazi Jewish heritage. Read more…

I was scheduled for a lumpectomy next Friday for my ER/PR + and HR- breast cancer but today the genetic counselor called me with some devastating news and that is I have the BRCA-2 gene mutation. I haven’t spoken to the surgeon yet but I’m assuming I will have to have a double mastectomy and I have been crying we unite a…

I learned through genetic testing after getting diagnosed with IDC that I had the BRCA2 mutation. The genetics counselor said it had to have been passed down from my father or mother and they would have had it passed to them through their parents. My dad died at 47 of a heart attack but my mom died in her 80’s of a…

Not quite 24 hour post surgery including 2 lumpectomies and sentinel node. (All left breast) Unfortunately it is Memorial Day Weekend, so hard to get a hold of my surgeon. I am looking for information some of you were told about what kind of exercise, movement, range of motion etc. are allowed/recommended starting Day 1…

Obesity May Increase Breast Cancer Risk Even More in Women With BRCA Mutations Mar 22, 2023 Obesity may increase breast cancer risk even more in women with a BRCA mutation, who are already a high-risk group. Read more...

Obesity May Increase Breast Cancer Risk Even More in Women With BRCA Mutations Mar 22, 2023 Obesity may increase breast cancer risk even more in women with a BRCA mutation, who are already a high-risk group. Read more...