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I am lost and scared that my next option is chemo. Emotional Yo-Yo and I have chemo PTSD
Hi there i just need to vent my fears. Not even 2 years with MBC and i am about to quit all treatments. Emotional Yo-Yo takes tall. Back in 2016 chemos were rough but i was going for the win. But this time around is different. There is no end of treatment and there is no win per se. I am lost and scared that my next option…
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CDK 4 6 inhibitor for Stage 2 ILC
Hi Everyone, I was wondering if anyone with stage 2 ILC was prescribed CDK 4 6 inhibitor. My sister was diagnosed with stage 2 ILC. Her oncologist prescribed her only AI but another doctor that she got second opinion from recommended CDK 4 6 inhibitors + AI because her ILC is 100% estrogen positive . Did anyone with early…
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How long on a CDK 4/6 inhibitor (Ibrance/verzenio/Kisqali)?
I’m sure this info is buried deep in the various stage iv threads, but I’m hoping people will post their experiences and success stories here. I think the median from the initial studies was about 2 years, but obviously there is more real world experience as time passes. Thank you!
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Treatment After CDK4/6 Inhibitors
Treatment After CDK4/6 Inhibitors Dec 5, 2023 Medical oncologist Stephanie Graff explains the treatment options available after a CDK4/6 inhibitor stops working. CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer. The CDK4/6 inhibitors are: Ibrance…
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Progression after ribociclib (or cdk4/6) and letrozole
Hi I had her2 neg er+ breast cancer in 2018. In 2022 i had recurrence in my bones (all over with 3 collapsed vertebrae) and liver. I was on ribociclib and letrozole that worked really well, pet was negative and most metastasis disappear. In August I had liver recurrence. Blood test and markers are ok and i feel well so i…
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Beginning Targeted Therapy? Start here.
Please start a new post/discussion for a targeted therapy that you'd like to discuss, if you don't see it here already, so others can join in with their experiences. Note: If you are Stage IV (metastatic), there are many threads addressing these medications for Stage IV patients in the Stage IV forum you may find helpful.…
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Phase 3 SONIA Trial Challenges the Routine Practice of Using a 1st Line CDK4/6 Inhibitor
Those with HR+, HER2- MBC may find this interesting! The Phase 3 SONIA study of 1,050 patients with HR+, HER2- MBC evaluated progression free survival (PFS) and overall survival (OS) from the initiation of first line treatment through failure of second line treatment. It compared two groups of patients. One group took the…