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Oct 1, 2016 12:29PM
Oct 1, 2016 12:31PM
My dear chat room sisters: There is not one study but several that indicate that, depending on the type of cancer, stage, receptors, etc, persons with MX may or may not benefit from radio, chemo, and cancer-controlling experiences. As you have noted, not everyone responds well to AI. I am on Arimidex and is causing me a lot of hand cramps and joint pains and decided to stay in it. I have read many, many articles on chemo and radio and rejected chemo; I was evaluated for radio and the lady sent me for a conventional protocol of 35 sessions which I will negotiate because the amount of rad, the equipment they use, and the logistics of the whole thing is too much. I had radical MX of right breast, sentinel biopsy of lymph nodes (in which the OS removed the only contaminated lymph node under the axilla), and in the PET/CT scan they found two more nodes on the supra-clavicullar fossa. That is the only region in which there is cancer activity. I will be more benefited by a partial breast rad tx or hypofragmentation, especially when they know that excessive rad can cause cancer to any of us. I sincerely have even told everyone, at the first burn, I drop out of tx. I still have a friction burn from two and half months ago and it has not cleared nor the skin has regenerated. I don't want that for my body. Not everyone reacts equally to rad or chemo, so we must be very cautious. I have had acquaintances that have died of chemo effects.
If the physicians have explained quite well the interpretations of Mammaprint and Oncotype results, chemo only adds up to the percentage of survival of women using tamoxifen. The percentage added depends really on the score one gets, according to the study's graphs. In my case I was 26 (Onco) and -.526 in Mammaprint (intermediate and high risk, respectively). However, the percentage of added "survival rate" it was 8 % on the first and 12% on the second. If you really ask me how I feel about being intoxicated or burned inside out for a 8% (12%) in chemo and 4% in radio, I will tell you the risks outweigh the benefits of chemo or radiation. They have to give me more valuable info to make a wise decision. I don't want the RO chasing cancer ghosts in my body just for the sake of a protocol because she thinks I have millions of cancer cells when I might have a few thousands. I need to be sure she won't create millions of them in trying to kill the thousands I have within me. I do believe in personalized medicine and it means that the whole tx is personalized.
The reality is that Mammoprint or Oncotype do not consider rad tx in their graphs. When I checked on the videos of physicians directing oncology sites in medical centers, they expose that in women with radical mx and less than four nodes, the added survival rate is only 4 per cent.compared to those who had mx and no rad tx at all, another time for me to think about risks and benefits. The RO who evaluated me sincerely told me that after rad tx, physicians keep checking on patients because the aftermath of rad tx.: cancer, pneumonitis, damage to heart and lungs, usually of the permanent type, exacerbation of osteoporosis, bone cancer, and many, many other undesirable long term side effects of rad. Chemo is also full of those too. So if your Dr. tells you that under your circumstances, you do not need the RT or chemo, don't push. Even going thru the chemo or rad, does not assure us of not having recurrence. And, if you go thru, there is an added percent that you may develop another type of cancer depending on the chemo agents MOs use.
So please, dear ladies, be careful. Ask, ask, and continue asking. It is hard to think that we may have some kind of responsibility on the kind of tx we receive, but is true. Drs. are not the the sole responsible for tx, we are whether we ask, inform ourselves or do the right things to achieve the best results. Hiding ourselves is not the best policy. Giving an informed consent is. And my best diatribe goes to: the ostrich. They don't hide the head in a hole to hide from danger. When they put their head in the hole, they measure distance from danger, type of danger, and a lot of info they obtain before running in the right direction.
5/4/2016, IDC, Right, 4cm, Stage IIA, Grade 1, 1/3 nodes, ER+/PR-, HER2-
6/1/2016 Arimidex (anastrozole)