ESR1 mutation treatment options and new SERD/SERM research
I was asked to start a thread about the ESR1 mutation that many ER+ survivors find in their genomic testing. I have the specific mutation of ESR1-Y537S. Which can make me not respond as well to AIs and even Faslodex shots according to my reading.
This resistance to estrogen blocking therapies is something I am interested in finding out more how to overcome. In my specific case I have progressed on all 4 lines of therapy- 2 with faslodex.
So I thought we could start a thread that highlights research articles, patient stories, clinical trials for the new SERDs that may overcome resistance and general support.
I will gather some of my info and post again soon. In the mean time please post your experienceshere for us to share.
My youngest daughter is studying to become a counselor and told me today, “We learn better in Community where we can share, care and grow!"