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High Dose Trastuzumab + Pertuzumab for HER2+ Brain Mets

olma61
olma61 Member Posts: 1,026
edited May 2021 in Clinical Trials, Research News, Podcasts, and Study Results

“In the phase II PATRICIA trial reported in the Journal of Clinical Oncology, Nancy U. Lin, MD, and colleagues found that pertuzumab plus high-dose trastuzumab produced central nervous system (CNS) objective responses and clinical benefit in 68% of patients with HER2-positive metastatic breast cancer with progressive brain metastases.“

Full article -

https://ascopost.com/news/may-2021/pertuzumabhigh-dose-trastuzumab-in-patients-with-her2-positive-metastatic-breast-cancer-and-progressive-brain-metastases/

Report of study results (pdf file)

https://ascopubs.org/doi/pdfdirect/10.1200/JCO.20.02822

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