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High Dose Trastuzumab + Pertuzumab for HER2+ Brain Mets

“In the phase II PATRICIA trial reported in the Journal of Clinical Oncology, Nancy U. Lin, MD, and colleagues found that pertuzumab plus high-dose trastuzumab produced central nervous system (CNS) objective responses and clinical benefit in 68% of patients with HER2-positive metastatic breast cancer with progressive brain metastases.“

Full article -

Report of study results (pdf file)