ER+, menopause, and severe depression
Good evening all,
I had a stage III ER+ diagnosis in 2004, so incredibly fortunate to be 18 years' NED last February. Here's the thing, I refused oophorectomy because I was terrified about quality of life by going into instant menopause at age 35 after having extremely high estrogen since birth I guess. I spoke with a number of high estrogen, younger women who had horrible effects from ooph and I felt like it was just too much. I always figured I would be better off going in to menopause naturally, if that time came for me. So, that has apparently now happened, or I'm at the end of perimenopause, and I am in the most severe depression of my life. Add to that, everything that could possibly go wrong has, all at once, like things go sometimes, but what has changed is that I am completely incapable of getting out of this funk.
I took Celexa for panic attacks for about six years, these started during chemo and finally became so disabling that I tried meds, which worked great. Recently, maybe last 6-8 months, I have entered a depression so severe that I am unable to cope. I was started on buspar with the Celexa, then Celexa was stopped and Prozac added to buspar. No improvement. Prozac dosage doubled. No improvement. Now wellbutrin is going to be added to Prozac. All the while, I'm thinking this is definitely hormone related, but of course I am not a candidate for HRT. I'm wondering, has anyone tried a low dose ER for severe depression, because nothing else was working? I am more sure than ever that passing on the ooph was the right thing for me, but if this is how I'm going to feel from now on, I don't feel like I want or am able to do it. This is not a life. I know an ER+ person asking for estrogen sounds crazy, but I feel that I have gone crazy and if small amount of estrogen would stop this, I wouldn't hesitate as of today. Anyone have similar experience or thoughts? I would really appreciate hearing them!!